Plan of action and budget for 1991

Il, 0nchocerciasis Contro'l Programme 'in l{est Africa Progranune de Lutte contre I'Onchocercose en Afrique de l'Ouest ,1 JOINT PROGRAMME COMMITTEE Office of the Chairman JPC-CCP COMITE CONJOINT DU PROGRAMME Bureau du Pr6s'ident JPCl 1 .4 Original: ENGLISH September 1990 JOINT PROGRAI,IME COI,IMITTEE E'leventh session Conakrv. 3-6 December 1990 Provisional asenda item 11 PLAN OF ACTION AND BUDGET FOR 1991 I I l} I ONCHOCERCIASIS CONTROL PROGRA},IMEIN WEST AFRICA PLAN OF ACTION AND BUDGET FOR 1991 TABLE OF CONTENTS 1. INTRODUCTION.. 2. OVERVIEW OF THE PLAN OF ACTION 3. PLAN FOR IVER},IECTIN TREATHENT... 4. GENERAL CONSIDERATIOT{S ON THE PROPOSED BUDGET FOR 1991 5. ESTI},IATED COST BY PROGRA},IHE ACTIVITY. 0cPl90.1 Pase 3 5 f I 19 19 23 29 34 37 39 12 45 46 48 50 51 52 5.1. 5.2. 5.3. 5.4. 5.5. 5. 6. 5.7. 5.8. 5.9. 5.10. 0ffice of the Director. Vector Control Unlt. Epidemiological Evaluation Unit. Biostatistics and Information Systems Unit. Socioeconomic Oeveloprent. Onchocerciasis Chemotherapy Project. . . Administration and Support Services Unlt. Administrative support costs Geneva. Statutory meetings. Capital Costs. ANNEXES I. OCP ORGANIZATIONAL CHART. II. RATES OF EXCHANGE OF THE US DOLLAR 1981-1990.. III. AVERAGE COSTS USEO FOR BUDGETARY CALCULATIONS.. IV. NU},IBER AND PERCENTAGE OF OCP STAFF }{EHBERS BY NATIONALITY AND SEX AS AT 31 l,tAY 1990.. V. COST OF PERSONNEL FROI.I 1981 TO 1991 VI. AERIAL OPERATIONS FROT,I 1981 TO 1991. VII. IIIAP - PROPOSED VCU PLAN OF OPERATIONS FOR 1991 VIII. VCU ENTOI,IOLOGICAL EVALUATION NETWORK - 1991 IX. I.{AP - IVER},IECTIN }IASS TREAT},IENT PLAN FOR 1991 53 54 55 56 57 59 60X. VEHICLES IN OPERATION FROIII 1981 TO 1991 , ocP/90.1 Page 2 TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE + LIST OF TABLES 1. BUDGET BY PROGRAMTIE ACTIVITY.. Pages 14 162. BUDGET BY CATEGORY OF EXPENDITURE... 3. BUDGET FOR 1991 - SUM}.IARY BY PROGRAI,I},IE ACTIVITY AND BY CATEGORY OF EXPENOITURE. 18 4. OFFICE OF THE OIRECTOR. 21 5. OFFICE OF THE OIRECTOR - SUI,II,IARY BY CATEGORY OF EXPENOITURE AND BY SECTION 6. VECTOR CONTROL 22 28 7. EPIOEI.IIOLOGICAL EVALUATION. ... 33 E. BIOSTATISTICS AT{O INFORT{ATION SYSTEHS.... 36 9. SOCIOECONOHIC DEVELOP},IENT 38 10. ONC}OCERCIASIS CHE}OTHERAPY PROJECT 11. ADI.IINISTRATION AilD SUPPORT SERVICES 12. ADI,IINISTRATIVE ANO SUPPORT SERVICES - SU}4I,IARY BY CATEGORY OF EXPENOITURE AND BY SECTION 13. ADI'IINISTRATIVE SUPPORT GENEVA 14. STATUTORY HEETINGS. 15. CAPITAL COSTS. 16. BREAKDOT{N OF CAPITAL COSTS TO ACTIVITIES. 43 41 44 45 47 49 49 0cP/90. I Page 3 1. INTROOUCTION 1.1. The P'lan of Action and Budget for 1991 w'i'l'l 'lead us to the threshold of the fourth Financ'ial Phase (1992-1997) now under preparation. According'ly, the Plan, whi]e ma'intaining continuity w'ith the past in the framework of the modified Plan of Operations for the third Financial Phase (1986-1991), adopted by the JPC1 at its ninth session (Dakar, December 1988), will in some ways be a key to the future of the OCP.. Longer-term options have therefore a'lso been taken into cons'iderati on. 1.2. Thus the resu'lts obtained so far, regard'ing both vector contro'l and ivermectin distribution, have been the subject of an in-depth evaluat'ion. The epidemiological situation has been examined on the basis of the most recent data.It has also been necessary to take into account the increase in the costs of most of the components of the Programme, in the face of the budgetary constraints which exist despite the generosity of the donors. 1.3. All these scientific, technica'l and economic factors have shaped the Programme for 1991 which will be a nelr stage towards the attainment of the first obiective of the Onchocerciasis Contro'l Programme, that is the elimination of onchocercias'is as an important public health problem and as an obstac'le to socioeconomic development in the whole OCP area. Likewise, everything possible wi'll be done with a view to pursuing the second objective, 'i.€., the e'limination of the risks of future recrudescence of the disease. Measures will therefore continue to be taken to strengthen the capability of the Participating Countries to maintain the ach'levements of the Programme when devo'lution takes place. 1.4. Larvic'iding has been stopped in the greater part of the initial Programme area. The problems of reinvasion were solved in 1989 by extending 'larviciding operations to the reinvas'ion sources. 1.5. It should be noted that the further computerization of the hydrological data and the optimization of aerial 'larviciding have1ed to an improved cost- effectiveness in vector control operations. 1.6. In para'l'leI with larviciding, where the epidemiolog'ical situationjust'ifies it, mass ivermectin treatment campaigns make morbidity control irunediately possible. The drug has proved to be effective, without serious side- effects, and amenable to large-scale app'lication. These campaigns are carried out 'in the extension areas and in certain parts of the initia'l area where the intensity of infection has not reached a sufficient'ly 1ow level part'icu'lar1y because of the re'invasion phenomena that preceded the extensions. 1. JPC : Joint Progranrne Committee 2. OCP : Onchocerciasis Contro'l Programme 0cP/90. I Page 4 1.7 . In the initia'l Programme area, where transmission has been v'irtua1ly interrupted, epidemlological evaluatlon activities in 1990 inc1uded an in-depth study of areas where it is planned to cease larviciding. This effort wil'l be continued in 1991. New village networks have been se'lected for long-term surveillance. In the extension areas, an epidemiological mapping has been made mainly to'identify communities at risk of onchocercal blindness for future ivermectin distribution. Almost al'l the communities that need chemotherapeutic intervention have been treated at least once. 1.8. As regards socioeconomic activlties,OCP wi'll continue to co1'lect baseline data in the western extension area and facil'ltate comnunications between the national authorities and other actors concerned wlth the Prograrme. Nat'lonal development stud'ies are being prepared following the regional studies undertaken by the Cormittee of Sponsorlng Agencies. 1.9. The Onchocerciasis Chemotherapy Project (OCT) wi'll continue its progranme of research and development with the aim of provlding a safe and effect'ive macrofilaricide for onchocerciasis. If precllnlcal toxicology of compound CGI 18041 proves satisfactory, clinical trials on volunteers and onchocerciasis pat'ients will cmnence in 1991. A major effort to increase the number of compounds screened for anti-filarial activlties trill require that a part-time consultant be employed in Geneva, together w'lth a facifity to store and shlp compounds to screening laboratories. 1.10. In the search for a constant improvement of cost-effectiveness,particular attention is accorded to management seminars organized both for theinitial OCP area and, as an innovation in 1990, for the western extension. During the seminars, emphasis is laid on the application of baslc management principles. Besides, special importance is given in OCP to computerlzatlon, personne'l training, and the tightening of financial control so as to achieve ever-lncreasing effectiveness in the use of resources. 1.11. Burkina Faso, l.lali and Niger have already presented their devolution plans which have been adopted by the Jolnt Programre Cormittee. These plans, which are awaiting financing, are based principally on epidemiological surveillance and integrate onchocerciasis control into prograrmes for the contro'l of other cormunicable diseases. Benin, C0te d'Ivoire, Ghana and Togo have also prepared the'ir draft devolution plans. 0cP/90.I Page 5 2. OVERVIEW OF THE PLAN OF ACTION 2.1. In order to faci'litate vector control operations, a nelJ del imitation of the eastern and western operational zones has been defined, re-establ'ishing a better work distribution between the two zones. This new del'imitation can on'ly befully effective at the end of the 1990 rainy season. The 1991 budget is based on the old delimitation, prevailing at the time of the budget preparation. However, this de1imitat'ion of zones, which has pract'ical advantages, has no budgetary impl ication. 2.2. In the orig'inal Programrne area, larviciding wi I I be continued in certainparts in the east and south-west which had been subjected to reinvasions before the extensions came into effect. In the southern extension, vector control operations wi'll be continued as usua'|. For the western extens'ion, operations wi'll cover the greater part of Guinea, and almost the whole of Sierra Leone. In the other areas of the western extenslon, no'larvic'iding wil'l be performed, but ivermectin distribution wil'l be intensified. 2.3. Ivermectin mass treatment wi'|l be carried out in a'l'l the areas where there is an unacceptab'le risk of onchocercal blindness. The activ'lties wi'l'l be performed by nationa'l teams with OCP support. Non-governmenta'l Organizations (NGOs) will a'lso be involved in the drug distribution. The national health authorities and OCP, wi'll study other means for ivermectin d'istribution in the less endemic areas of the northern part of the western extension. Furthermore, the possibi I ity of interrupting transm'iss'ion with f requent ivermectin distribution wil'l be studied. 2.4. In-depth studies will continue in the river basins'in the initia] Programme area where larviciding interruptions are planned, in order to reduce to the minimum the rlsk of a hasty suspens'ion of vector control. In all the areas where vector control is to be interrupted, neh, v'i1'lage networks wil'l be put under epidemiolog'i cal survei I'l ance. 2.5. The analysis of epidemiological and entomological data, so as to support decision-mak'ing as regards the continuatlon or interruption of larviciding, w'i11 remain one of the main activities of the B'iostat'istics and Information Systems Unit (BIS). Epidemiological model'ling w'l'll be used'intensively to that effect. Bes'ides, the Unlt w'lll continue to consolidate the data process'ing achievement of OCP and prepare new necessary programmes. 2.6. The assistance for socioeconomic development of the areas protected or to be protected from onchocerciasis wi'll sti'll be coordinated by the Sponsoring Agencies. OCP will cont'inue wlth the liaison role which is now incumbent upon it. ocp/go. t Page 5 2.7. The OCP training programme, whether forma'l or in the f ie'ld, wi1'l focus on the various aspects of devolution. OCP fel'lowships will be given for courses run in institutions'in Africa. 2.8. OCP wi'll continue to conduct or finance studies and research'in the f ie'lds of vector contro'l (larvicides, the vector and the parasite), hydrology, hydrobio]ogy and epidemio'logy. The Onchocerc'iasis Chemotherapy Project (OCT), for which OCP wil'l continue to provide funds in 1991, will carry on the research for the development of an effective macrofilaricide. 2.9. At a time of increasing costs and uncertain currency fluctuations, stringent management - supported by computerization - is still of the essence. 0cP/90.r Page 7 3. PLAi{ FOR IVERI,IECTIT{ TREATHENT 3.1. The evaluation made in 1989 of the effects of ivermectin mass treatments has demonstrated that the drug is an efficient tool for morbidity control, and that it is safe and acceptable. Furthermore, after three rounds of yearly drugdistributions, treatment coverage remains close to 603, a percentage sufflcient to ensure the protection of the populations against the risk of onchocercal bl indness. 3.2. Experiments conducted until now indicate that mass treatment with ivermectin alone cannot interrupt transmission of the paraslte. However, thedistribution of ivermectin at more frequent dosing intervals, planned in certaln zones of the western extension area not submitted to larviciding, will keep theparasite load ln the human body at a low level; thls contributes to reducing the chances of transmission. l,loreover, according to model forecasts, ln case of recrudescence of onchocerciasis ln a focus previously subjected to 14 years of successful vector control, ivermectin mass treatment can interrupt transmission,provided that the episode of recrudescence is detected early. 3.3. OCP, in collaboration with the Partlclpating Countries, will continue to undertake comnunity-wide distrlbution of ivermectin ln all the areas of the Prograrme where there is an unacceptable risk of onchocercal bllndness, identified by extensive epidemiological mapping. The morbidity control programe based on ivermectin distribution wlll be carried out by national teams supervised by OCPpersonnel. In a few river baslns, ilGOs vlll be involved in the dlstrlbutlon of the drug. It is expected that in 1991 approximately 400,000 people will beprotected with ivermectin mass treatment. 3.4. In the northern part of the western extension area, which will not be suhnitted to larviciding, delivery of ivermectln rill be intensified. An estimated 65,000 p€rsons will be treated in 1991 by means of active mass treatment (alldetails are given in Section 5.3 of this document). In some places to be determined, the drug will be distributed at more frequent intervals, up to three times a year to study further the effect of ivermectin mass distributlon on transmission. Particular attention will be given to epldemiological and ophthalmological evaluation. 3.5. The study of new methods of ivermectin dellvery in less endemic areas will be encouraged. Ivermectin distrlbution vill be l{nked to fteld activities almed at the control of other diseases. Passlve treatment will be available in the health centres located in the endemlc areas. These activlties yill be supported and coordinated by OCP which rill ensure timely supply and emphasize the need to keep proper records of the utllizatlon of the drug. I l 0cP/90 Page I 4. GENERAL CONSIDERATIONS ON THE PRoPOSED BUDGET FOR 1991 US $34,355,000 4,1. The Plan of Action and Budget for 1991 is presented by "Programe activity" (sections 5.1 to 5.10). l{ith a few exceptions, a "Progranme actlvity" corresponds to a major subdivision of the OCP organization chart wh'ich ls in Annex I. The Liaison Office in Geneva and the Coordinator's Office are inc]uded in the 0ffice of the Director. "Capital costs" are considered as a Programme activity. 4.2. Table 1 gives a year-by-year sunmary of the costs per Prograrme activlty for the whole of the Third financial phase (1986-1991). It shows the Prograrme activities in the same order as ln the organ'izatlon chart. Flgure 1 presentsgraphically the proposed budget for 1991 by Programe activlty. 4.3. Each Prograrme activity comprises a series of categorles of expenditure. Table 2 gives a year-by-year surmary of the costs per category of expenditure for the whole of the Third financial phase (the order of the categories of expenditure follows the OCP interna'l budgetary structure). Flgure 2 presents graphically the proposed budget for 1991 by category of expenditure. 4.4. Table 3 combines Tables 1 and 2 for 1991: surmary by Programne activity and category of expendlture. General remarks 4.5. The strict cost-saving principles continue to prevail in the preparatlon and execution of OCP budgets. To be incorporated in the budget, all personnel posts, and a'll activities involving expendlture, must be consldered essential for the achievement of the objectives of the Programe. 4.6. The proposed budget for 1991 amounts to US $34,355,000. The average costs are shown in Annex III. The presumed annual inflat'ion rates, together with statutory requirements as regards personnel and consultants, have enabled the following percentages of increase to be established compared to 1990: - Professional staff members - General service staff members - Consultants - Supplies, foreign procurement - Supplies, local procurement - Services 9.92 17.32 10t8r 102 5Z 0cP/90. I Page 9 4.7. The approved budget for 1990 is US $30,770,000. The increase from 1990to 199f is therefore US $3,585,000, i.e. 11.65I. Part of this increase is due to the dollar exchange rate as explained in the next paragraph. The other causes of the increase, mainly the evolution of the costs of personnel services, the purchase of larvicides, and the intensification of lvermectin distribution in the northern part of the western extension, will be explained further down ln this document. Dollar exchange rate 4.8. Any year, the estimated rate of exchange of the CFA franc to the US dollar, has a considerable impact on the total budgeted amount. In 1990, the percentages of OCP expendltures per currency are as follows: US dollar CFA francs Other currencles 285 285 31r 59r 10r A comparison of the 1990 and 1991 budgets shovs: CFA exchange rate Budget (US $) 1991 285 34,355,000 1990 338 30,770,000 Increase 1991 3,585,000 If the exchange rate of 285 had been chosen for 1990, the budget uould have amounted to US $33,617,000 taking the above percentages of expenditures per currency into account. At an equal exchange rate for the tro budgpts, the folloving comparison would be had: 1991 I 990 34, 355,000 33,617,000 Increase 1991 738,000 Annex II shors the percentage evolution of the US dollar exchange rates frcm 19E1 to 1990. CATEGORIES OF EXPEIIDITURE 4.9. A reviex of the categories of expendlture facilitates the understanding of the whole budget and allous the main causes of the increase in 1991 in cmparison vlth 1990 to be defined. The order followed in the reviev hereunder is that of Table 2. 0cP/90. I Page l0 Personnel services us tl1,334,500 4.10. After the considerable reductlons ln staff in recent years - from 1987 to 1989, 301 for the professional staff,25Z for the general services - it appears, with very few exceptions reflected in the 1991 budget, that the critical threshold has been reached. The following table gives the personnel estab'lishment approved in previous years and that proposed for 1991: TPPIOI'ED PENSOfi EL ETTAILITIIIG}TT Pr!,ta!alq|rl Oflrrl rralo ta aa ,t ,l aa at aa aa :: Totrr i i thlt. a a :TOTAL 22 ,i aa aa 5 !! a a I I I ta ll a a a a I lt aa !r'tc irtrT lrmt irrtt ittto :i tttt i:tt t i:::i!!Ptqad:: rt7I tErt !ttI ttot a tto t tt a at ttI aa al i rrtr !: rtrl i: lPrSOd! iPropodi : It DTR vcu E?I ltE BCO tl tc tt t7 5 a to 5 d a a t2 It to act a2 t 2 'l tt c t 2S 2 at z! !! lltt 2:: tt aa o.5 ii c.5 i i sto o.5 taat ro.l : ! aa aa .r2 !! aa tt 27 ii attt 4 !i 5 t a 2 zi2 ii .47 tl aa .:! L tl aa 2 !! !o7 t5 t t c5t 2l 22 I t.52 t tt tc 2 t tl t t t t t C 17 t t I t a a aaa a tt 2iGI rDr t a al t t tt c7: J2 722tt7 co? : m :: t3 ta aal-l attl 5.. i 512.5:: trl :: 553 4.11. The differences between the 1991 total (553) and that of 1990 (555.5) are explained under the respective Prograrme activities (Office of the Director, Epidemiological Evaluation Unit). Thus, desplte the strict containment of the number of posts, an increase of US $1,334,000 in the costs of personnel servicesis expected. This amount ls beyond the control of OCP which is bound by decisions taken in the United Nations system. For 1991, this concerns increases in basic salaries and in certain allowances for the professional staff (in alt 9.9x). As regards the general service staff, the experience ga'ined in the Prograrme area makes it possible to calculate the increases expected in 1991 (17.3x). 4.12. The number and percentage of OCP staff by sex and country of orig'in as of 31 May 1990 are sumrarized in Annex IV. Annex V illustrates the cost of personne'l services, from 1981 to 1991 excluding consu'ltancy services. aa aa att! E] a a I a I I at al a I t a la a-l-l-t-l-a-l t-r a-a-l-t-a-a t- - laa! atla- tla! !: .2 a a a aa aa a a a i il aa aa -t-l-l-l a-a t-!-a-a-l-l l-l a-l I 0cP/90. I Page ll Consultancv services US $1,202,000 4.13. These services include: - consu'ltants who strengthen OCP teams in activities related to ivermectin distribution, or who contribute as experts to research work (in the fields of insecticides, entomology, hydrology, hydrobiology and cytotaxonomy) - short-term profess'ionals: a total of ten is planned for 1991 - Un'ited Nations Volunteers (UNV'S): two in number, in the f.lelds of epidemiology and hydrology There is an increase of US $440,000 in this category for 1991, due to the addition of four short-term professionals, and an increase in consultant services used bythe Epidemiological Evaluation Unit and the Onchocerciasis Chemotherapy Project. Operational travel US $I,3ZS,OOO 4.14. There is an expected decrease of US $59,OOO compared to 1990. This is attributable to the strict measures adopted on duty travels. Each mission must be considered essential. Contracts US $1,S33,OOO 4.15. This category covers research contracts (e.g. screening of newinsecticides and new formulations), service contracts (e.g. aquat'ic monitoring, Argos teletransmission, maintenance of hydrological stations), and contracts signed as part of the Onchocerciasis Chemotherapy Project). A decrease of US i324,000 is to be noted in comparison with 1990. Aerlal ooeratlons US $6,g15,000 4.16. This category comprises the aerial contract (helicopters, Turbo Thrushes' liaison aircraft) and fuel. The estimated flight hours amountto 8 350, compared to 8,300 hours in 1990. 4.17. It should be recalled that the 1990-1992 saw an increase in the cost of $555 to US $777 (i.e., 402 increase) for $666 for non-guaranteed hours (i.e., S0I the costs of aerial operations frorn l98i aerial contract renewed for the periodflight hours (excluding fuel) from US guaranteed hours and frmt US g4/+4 to US increase). A diagram showing the trend into 1991 is given in Annex VI. us $2,510,000Ooeratlno costs 4.18. These are costs related to the logistic needs of the Programre (e.g. vehicle fuel, spare parts) and to the administrative infrastructure (e.g. rent, electricity, water, telephone, watchmen). There is an increase of USg7O,000 due tothe rise in the costs of some of these services, and to the intensification ofivermectin distribut'ion in the northern part of the western extension. 0cP/90. r Page 12 Larvi ci des us $6,120,000 4.19. Considerab'le larvicide reserves, accumulated 'in previous years, hrere availab'le in 1989. In 1986, the Programme had to face temephos resistance in the savanna species of the blackf'ly and this phenomenon led to the accumulation of adequate stocks of rep'lacement'larvicides. Sufficient reserves also had to be put in place when'larviciding tras extended to the whole of the southern extens'ion area and part of the western extens'ion area. Furthermore, larvicide savings were made as a result of the optimization of the spraying circuits - relying on a hydrometric and aerial operations computer system - increasing the reserves p ropo rt i onate I y . Because of the quantities available thereby in 1989, the 1990 budget estimate for 'larvicides was estab'l'ished at US $4,100,000, i.6., the lowest amount for the Third financia'l phase. Thus, purchases lrere comparatively low in 1990 rhile the reserves had to be drayn on so as to treat, with a sufficient intensity and duration, the rivers in southern Sierra Leone and Guinea which are permanent, have a ra'iny season high-discharge and correspond to hyperendemic foci. Consequently, the level of the reserves to be carried over to 1991 wil'l be greatly reduced. To meet the requ'irements which remain unabated, an amount of US $6,120,000 wlll thus be needed in 1991, i.€., an increase of US 02,020,000 compared to 1990 (see section 5.2.4. for detalls on the types and quantitles requi red) . suoolles us 0555,000 4.20. This concerns all perishable items as opposed to capltal costs. It 'ls estimated that an amount that is US $6,500 less than that of 1990 should meet the requi rements. statutorv meetlngs us $305'ooo 4.21. The budget remains unchanged conpared to 1990. Fel lowshlos and trainins us $316,000 4.22. The budget, which has sllghtty increased, by US $16,000, will cover the continuation of current fellowships, new ones and fie'ld training. l{atlonal teams US $1'000'000 4.23. The whole of the OCP personnel is found in the in'itial Prograrme area. In the western extension, the governments of the Participating Countries (Gu'inea, Guinea Bissau, l,lali, Senegal, Sierra Leone) put national teams at the disposa'l of the Prograrune and they remain employees of their governments. They work under the technical supervision of OCP. The national staff members receive their salaries and the different allowances attached to their status from their governments, while OCP pays them a flat allowance as well as per diem when they travel outs'ide their duty stat'ion. The Prograrme also provides the teams w'ith vehicles (purchase, servicing, repa'ir, fue'l) and other equ'ipment. 0cP/90. I Page 13 4.24. Nationa'l staff thus made available, for entomo'logical, hydrological and epidemiological activities, is as fo'llows: vcu EPI 1 986 1 987 1 988 1 989 1 990 Proposed for 1991 225 154 154 364 288 323 73 (part-time) 85 (part-time) 78 (part-time) An increase of US $130,000 compared to 1990 is justifted by plannedintensification of lvermectin distribution campaigns. This amount lncludes trave'l of nat'iona'l medical staff working outside the national teams, to be employed in the northern part of the western extension. Other cateqorles 4.25. Administrative support in Geneva and capital costs will be dealt wlth under Prograrrne activitles. Budget sumraries 4.26. The proposed budget requlrments are surmarized in the following tables and figures: Table I - Budget by Prograrme Actlvlty Flgure 1 - Budget by Prograrme Actlvlty Table 2 - Budget by Category of Expendlture Figure 2 - Budget by Category of Expcndlture Table 3 - Budget surmary by Progranme of Actlvlty and Category of of Expendlture Further detai'ls are provided in Tables 4 to 16. 0cP/90. I Page 14 ItBtt r BIJOOEI 8Y PROSRIIII ACIIVITY (lJs t) ituruExpcnd diturcErpm Irpand i tu re tgtE Erpand i tu rr l9E9 r9t0 t-r-t-t 935 ,326 l, lt2 2, l05,{16 305 ,000 Iotrl t99 r -l t-l ApproYcd ,000 2 I ,6E2,000 1 , {06 ,000 085,000 30,1 10,000 Proposad Progrure Activity t9t6 r 981 9t6 to l09l 0fficc of thr 0iructor Ycctor Control lpiduiologicll cvrlurtion Eiostatistics I [nfo. systus Socioaconoric drvelopmnt Choothrryy Projact ldrinistrrtion t Support Srnicrs lfiinistrrtivr Support Costs Ganevr Stltutory lcctings Cuitrl Costs (l) t5 0t{ 9gE 100 t 2E,553 ,050, gll 5er il2 2r6 06 t0r 336 E3r 2l I,261,515 t0,63t 2,623,1{2 2,136 ,601 3l35, {{E, t5{20 ,210 1,969, 32t, 500 000 500 500 I ,6{l ,500 g{9,500 t26, 956, l,l5l, ,056 25 t62 E5E r52 3r8 rtc 9{3 2r3 30r 90r OI II 20, 109,335 2,566 t09 ,09 295,6t5 0tE IIg ,265 2$ r33 trE 36t 669 E{3 t2r 2tr Il gt9 ill 000 000 000 000 000 000t2 2,6t5,300 3t0,000 305 ,000 6lg, t 2 ,51{, 2,35t, t3g 2 505 t2 2 I t,6t0, 1 ,102 ,229,003 209 2t6 It0 til 25r 256 t0 2 633, 353 03t,500 t3{,6623, 6lfl9,605 lgplicd nscrrch rnd rnvironrcntrl nnitoring 2,fl1,2t{ I,ill,3lt t-l-t-t -t t-t IOTIT 25 , 5ll, l0g t3,t01,313 l2t,12t,2t3 l2l,t?9,55t l-t-t-t-t-t-t t-t t-t (l) CUitrl cost crgrnditurcs for 1986 to l9E0 rrr includrd in thr upcnditures of thr Progrur rctiuitirs rboYr. lycnoctin: 900,000 tdlrts utluld us 13 r trbltt, grovidcd frcc of chrrga bl hrck Shlrp ud hhn 3{,355 000 lote tl t, tt ll lt il il tt tl lt tt lt t5 ltltilttttlttlttilil ttilttltttilttttttilttltttillltt ttttll ttltltil tllttlllttttllllltlltttlttll 3 I I,ll 0cP/90. I Page 15 FIGURE 1 1991 BUDGET BY PROGRAMME ACTIVITY 8910 I 7 6 3 1 Offlce of the Dlrector 2 Vector control 3 Epldemlologlcal Evaluatlon 4 Blostatlstlcs & lnformatlon Systems 5 Socloeconomlc Development 6 Chemotherapy Profect 7 Admlnlstratlon & Support Servlces 8 Admlnlstratlve Support Costs Geneva I Statutory meetlngs 1O Capltal Costs 5 4 2 (US $) 1,24O,5OO 24,969,OOO 1,754,5OO 327,5OO 142,OOO 1,641,5OO 2,685,5OO 34O,OOO 3O5,OOO 949,5OO (Yo) 3.61 72.68 5.1 1 o.95 o.41 4.74 7.42 o.99 o.89 2.76 Total 34,355,OOO 100 0cP/90. I Page l5 ItBt t 2 TUOOII 8Y CIITGORY OF EIPIXOII|JRT (us ;1 Crtagory of crptnditure RICllRREII COSIS Plrsonrcl srnicos Consu ltrnts 0prrrtionrl tmval Contrrcts(nserrch I othrrs) Arrirl op:rations Oprrrting costs llnicidcs Suppl ias fitings hllorships and trrining lrtionrl lcus ldrinistrutivc Support osts - Gcnrvr Sub-total GtPIril. CoSTS 0fficc furniturr lrtr procssing cquignnt Uchiclrs Irchnicrl rquiprcnt luildings Sr!-totl I IOTIL Irprnd i turr r9t6 2lg,061 229,003 l-t-t-t-l-l-l 3ll ,2 l {2 t ,29 ,325 652 ,032, E9l 935 036 lI0 6tr t,006 ,t l,2l?, 5 3t t6 t2o , t05 3,1{l,922 9902t {til I I i2 I oe5I t-l-t-l-l-l-l lt ll ttprndihre | fi prnditunl [rpcnd itura r9tl t9tE -t-t-r 9,860,ilg I, lll,0l5 I 919 t ,026 , gl9 {II 9l ,060, 959 5 935 ,gEt 2,I36,523 5,31 1,906 2 ,0t6 ,099 l2t,02t 2{E,2lt t66,063 68,3t9 5il, 15 ,9{t ,llg,65l , {19,109 135,900 212,121 It5,5{8 I , 005, 2,112,310 1,013,3{5 2,215, Il6 231 369 600 522 3 0lEt3 5,051,321 g e6rI 2 {t9t0{3 tE2E6 IO269 ril, {0 II9 {66 il0 OEE t21 502 256 2tE {II t3 32 2l il2,163 l l, t2{ 23,030 1,05E,509 il3 0r9 2r3 03r tttt 32,03{,til 121,t35,t05 126,t21, tt 5t 63r 3tI t25 {93,9e5 g2I6 t685 I I 21, llg,55t 130,110,000 I 2l33, t0 1 ,313 92 I I i2 I lpprovcd r990 1 0,000,500 162,000 1 , 131,000 I , t5l ,000 15,000 {t0,000 I, lo0,000 50056 305,000 300,000 ,00020,6E5 25,000 35,000 15, 000 0t5,000 t-l 6 2 fi0,000 310,000 050,000 300,000 il t99 t 1 ,315 555 ,000 -t t-l l-l 33, {o5,5oo ,000 ,000 ,000 000 000 ,533 t20 ,000 000 000 3r6 000 3t0 Proposrd 33t,5oo I ,202 ,000 00025 2t -t 3t,355 -l ,t ,5 305,000 5{,100 650,000 000 000 500 000 9{g lt Iotal l9t6 to l99l l,95 5 , Ell 6, E10,229 , t28,563 I , l05 ,5lt {{3 ,255,09{ 599,933 ll3,l{3,125 ,59E 3 0t9, t3g 365,993 II635, l3 32 001 {03 I20 l6t3 32 62E 3Et3 556,030 ?02,30t 2t2 llE, 3 -t t-t -t t-r 3 2 tt tt| 6,t62,|u I tl I -l tt ll Ifl9,605,613 I ll I -l I { tt tt lt lt lr ll il tt tt tt tl tl l-l t-t , 500,57 il 53,0il 0cP/90. I FIGURE 2 PAgC 17 1991 BUDGET BY CATEGORY OF EXPENDITURE 4 15 (US $) (7ol 1 1011 16 17 7 5 1 Personnel servlces 2 Consultants3 Operatlonal travel 4 Contracts (rerearch & others) 5 Aerla! operatlons 6 Operatlng costc 7 Larvlcldee 8 Supplles9 Meetlngs 1O Fellowshlps and tralnlng 11 Natlonal teams12 Admlnlstratlve Support costs - Geneva 13 Offlce furnlture 14 Data processlng equlpment 15 Vehlcles16 Technlca! equlpment 17 Bulldlngs Total 11,334,5OO 1,2O2,OOO 1,375,OOO 1,533,OOO 6,815,OOO 2,51O,OOO 6,12O,OOO 555,OOO 305,OOO 316,000 l,OOO,OOO 34O,OOO 25,OOO 54,5OO 65O,OOO 21O,OOO lO,OOO 32.99 3.50 4.OO 4.46 19.84 7.31 17.41 1.62 o.89 o.92 2.91 o.99 o.o7 o.1 6 1.89 0.61 o.o3 34,355,OOO 100 13 r:!F,]a 1 6 2 3 4 0cP/90. I Page 18 IAErt 3 SIJOGII FOR I99I -SUIIARY 8Y PROOITITE ICTIYITY ilO CAIEGORY OT ITPIMilURI (us t) Crtcgory of crpcnd i tu ra RtcuRRilI CoSIS Pcrsonntl sarvices Consultuts Operrtionll trrvrl Contrrcts (resaarch I othrrs) lcrirl oprrations 0Frrting costs Insrct i cidcs Supgl ias Fcllor$ips rnd trrining lrtionrl Trus ldrinistratilr Support Yrctor cont rol -t- 6,E00,000 15,000 2, 000, 000 25 ,000 250,000 r09ruttlct ctorrt 60{,500 I ?0,000 0000, I I vity iP io I I I tpiderio- logicrl I rvrlurt. I 2t ,500 2 t0,000 ,{93,000 135,000 000 00000 00020 300,000 16,000 ,000 220,000 25,000 005t tttt ,2{0,500 i21,969,000 lltt 000 000 tit 23 000 000 6 o 00 000 000 000 000l63 Sub-totrl crPrft cosls 0fficl furnitun Drtr proccssing cquipnnt Uchiclcs Icchnicrl rquipnnt Cui ld i ngs 000 {,500 10,000 5 5 100,000 |t,000 l0,000 Sub-tottl {56 ,000 t5{,000 ttlIoltt ll,2{6,000 125,t25,000 1t,00t,500 ltt 5,500 I -t -r -l -l -l -r -l -r 15,000 -t -t -l -l -t -l -t - r 20t ,500 25, 000 000t0 20,000 000 000t2500t2l 500 000 000 000 30 2 l0 000 500 2 12,500 2 500 00il -t- 3t0,000 Adri n i s- trrt ion -l-r-r-l-l- {5,000 55,000 310,000 I I 1,011,500 I 3,025,500 tl-t-t-t- -l-t-l I,011,500 305,000 Chcm- thcrrpy rojoctiP I Stltuto ry leat i ngs I 35,000 tt tt ll tt tt ll tl tt Iotal r99l -t 226, 500 1E0,000 20,000 200,000 000 965,500 00030 35 ,000 ,31 '33 ,18 I ,00 I , 53t ,000 6,815,000 2,510,000 500 000 000 000 000 000 000 000 0, 000 000 35 000 6 , 1 20,000 3t0,000 33, {05, 500 5{,500 650, 000 505 3r6 000 tttlttlttttttlil 000 -t 00025 -t -t -t 00030 ,t t-t r lt tt g{g ,500 31, 355 ,000 l2 250,000 50 ,000 000 ,000 l9,000 2 3, 31{, 500 II lttt !Eiostrtir iSocio- Itics I Infoleconoric lsystns iOevclop. tt t5 lr il ll il tt l, l, tt il tt tt lt tt il tl lt lt tt tl lt lr tl tt lt tt 0cP/90. I Page 19 5. ESTI}IATED COST BY PROGRAHI,IE ACTIVITY 5.1. Office of the Director us $1,240,500 5.1.1. There'is no change in the P'lan of Action compared to last year. The Office of the Director will be responsible for the follow'ing functions in 1991: - general policy and Progranme management; - liaison with the statutory bodies, the Donors, the Participating Countries and the scientific cormun'lty; - coordination of a'|1 Prograrme activities, includ'lng research contracts, and socioeconomic projects; - information services and public relatlons; - training and administration of fellowships; - statutory meetings. Ilevolution 5.1.2. Devolution remains the key to the long-term success of the Prograrme.Its preparation occupies a pre-eminent place in various national and regional consultations, in meetings of the OCP statutory bodies, in seninars organized by the Prograrrle, and in the daily work of the Office of the Dlrector which, in 1991 as in the past, will play an active role in the process (training, technological support, in the implementation of the plans). This will be done in close collaboration with the t{llo Regional Office for Africa (AFRO) and particularly rith the Subregion I Office in Bamako (l,tali). Tralnins 5.1.3. As regards training, emphasis will be particularly placed on disciplinesdirect'ly related to onchocerciasis so as to enable the Participating Countries to assume, with all the chances of success, responsibillty for residual control activities during the devolution phase. Furthermore, the credits allocated for fellowships will be reserved solely for courses run in Africa. Field training w'ill be continued. Information 5. 1 .4. At the present stage, the Information service wil'l play a twofold role: - sensitization of the target populations on the devolution process, in collaboration with the Health Education services of the Participating Countries - continuation and strengthening of the information campaign aimed at the general public, the Participating Countries and the Donor countries through the means available (print media, radio, films, exhibit'ions). dcplgo. r Page 20 The Documentation Centre will continue to make documents avai'lable to internal and external visitors. It should be noted that the Office of the Director has since 1989 been translating all documents prepared by OCP. Personnel 5.1.5. To carry out these duties, the Office of the Director w'ill require: - four professiona'ls; - two short-term professionals (information and translat'lon); - slx and a'half general service staff members; - a part-time consultant for the preparation of the Plan of Operations for the fourth Flnancial Phase (1992-1997). Budqet 5.1.6. The proposed budget for the Office of the Director is US $1,240,500,i.e., an increase of US $58,500 as compared to 1990. This is due to increase ln staff costs (including an additional short-term professional), and to some increase in training. 0cP/90. I Page 2IIlELt r OFFICI OF IIII OIiECIOR (tjs t) Cltrgory of rrprnditure ltcuRRill cosls PERSoliltr SERllICtS Progrura 0ircctor Coordinrtor Scirntist (Olncvl) Infonrtion officer (l) ldrinistrrtivc Off icrr ldrinistrutivl Assistlnt Srcrctrry (0ancvl) Clcrl stanogruphcr 0rivrr Iuporrry stlff (Ganevr) Sub-totrl Sub-totll POSTS I Erpanditurs I teE6 ire87 irerE i1989 lteeo ileeri reE6 0rrde txpend i tu re 198 7 trplnd i tu re i Erpend i tu rc I 9EE r 989 rovrd r990 App 1 05, 000 95 ,000 t2E,000 Progoscd 1991 3, 000 636 ,000 500210 tl -t -t -t-l-l-t-t -t -r -t -l - ,2 .5 .5 .3 .3 .s .s .s .s 0 P P P P 0 G G G 1 03 ,000 il{,000 I 2 1,5 3,5 I t 2 I ,5 I I0,000 23,000 t00,000 t0,250 I I ,500 I 0,250 II,500 2l ,000 E2,500 33, 150 13,500 1 0, 250 -l -l -t -t -t -l -l -t -t 63, l2l 2t It t2 3EIE38,10, I I 5l I E , t93 t90, 5t6,91 2 ,0{2I6 , E53I6 l-t t-t 60{,500 lt 000 -t-l-l-l-t-t-t-t t-t 0 90, 000 50, 000 l0{,000 t 5,000 {0,000 300,0oo ll0,000 I 10,000 t 5, 000 25 ,000 3t6,000 96 ,301 {E,232 il,233 t6,3t2 lt t,6tt I 0{,5 33 5 ,56{ 6, 119 t 2 ,956 2{E, 2{ l 10,0 t t 6, l2t 23E, {66 66 ,362 13,203 12,126 ll,215 lE5,5tt l-t-t-t-t-t-t- ttE, 936 -t -t-t -t-t -t _t _t_ 56 3r3 t0 3E5 65{{E 599,000 -t-t t-l -t l-t IOIAI. I,035, I3l I -l -l -l -l -l -l -l-l -l -l - (l) A Public rclrtions rnd infonltion officr post rrs crratcd in t9tg Ihr incurbrnt is rutrinrd rt prcscnt rs r short-ten Profsssionrl (2) Iro Unitcd lrtions Yoluntacrs to rssist in thl distribution of ivcnectin rerr budgctcd in 19E9. One post fillad in Guinec-Bissru rhich rppcrrs undrr [P[ budgct (Idh I) 2t 2{ il r2 t l0 ,239,05{ t-t ll llI Conrultrnts ii Unihd lrtions Iolunttcrs (2)l| 0parrtionrl trrvrl II Contrrcts (gtrvices) i| 0pcrrting costs II Suppli* iI Frllorships rnd trrining i ll 2t ll il tl il lt tt tt il tt 5 I I I I I 2 I 3, I I 3 2 { I llttlrItil t2, lt lti 55t,t03 i 5r3,lr I I 929,160 il,lE2,0o0 I llE,lil tt 3l 96r I I lt, I 0cP/90. I Page 22 IABLE 5 OFFICE OF TllE OIRECTOR SU||IIARY BY CAIEGORY OF EIPEIIOITURE A}ID 8Y SECIIOII (us $) Crtegory of crpend i ture Informtion I rnd i docurentat i on Illrnrgerent 37,750 38,500 5 ,000 i onsScct ttneProg r 2 Geneva I irison 0nut ining and 0evo rt TOTAL t RECURRETII COSIS Personncl scrviccs Consul trnts 0pcrrtionrl travel 0pcrating costs Suppl ics Fcl lorships rnd training IOTAL 26,750 5 2 00037 25,000 0000 00003 60{ r70 0 500 000 000 000 5003r 0005,0 6 000 0005 5 ,000 ,000 ,000 0 0 25 ,000 3 4t{,000 00063 t- 2503t 250I 2 ,0002 I ,2{0 , 500 -t -t 5 -a-t-t-t- 0cP/90. I Page 23 5.2. Vector Control Unlt (VCU) us $24,969,000 5.2.1. The Joint Prograrme Cormittee (JPC), at its tenth session (The Hague, December 1989), had noted, following the advice of the Expert Advisory Conmittee, that "larviciding remains the proven method of onchocerciasis control resulting in imnediate interruption of transmission". t{hile recomnending that larvicidlng operations should be intensified in the extension areas, the JPC had acknowledged that certain river basins "were not suitable for larvicide treatments because of technical and,/or aeronaut'ical constraints, and because they were not likely to be sources of reinvasion towards areas which vere under vector control. In such areas, ivermectin distribtjtion was the most appropriate means of onchocerclasis control" (document JPC 10.3, paragraphs 38 and 39). Taking into account the advice of the Expert Advisory Comrittee approved by the JPC, areas where larviciding should be continued (part of the initial area and the southern extension), intensified (Sierra Leone and Guinea) or replaced by active ivermectin treatment (northern part of western extenslon area) have been defined. Areas to be treated (See map in Annex VII and VCU Entomological Evaluation netyork in Annex VIII) Eastern area lncludlnE the Southern Extension 5.2.2. In the eastern operational area of the initial Progranme area, thefolloring watercourses rlll remain under larvicidlng: - the Black Volta and the right-bank tributaries to the south of Noumbiel; - the Kulpawn and the Sissili and thelr tributarles located in Ghana; - the t{hite Volta downstream from the Nassia as yell as its tributary, the Kulda I; - the Oti downstream from the Koumongou as well as its tributaries(Koumongou, Keran, Kara and Ho); - finally, the tributaries of the Niger (Altbori and i,lekrou) to the north of latltude 11o45'N. In the southern extension area, to the vest of the Volta Lake, only River Pru will be treated. To the east of the Volta Lake, aIl the watercourses harbouring breeding sites of the S.damnosum complex will be treated with the exception of the smal'l montane rivers at the border between Ghana and Togo colonized mainly byS. squamosum and S. vahense. To sum up, therefore, in the southern extension area, larviciding wjll be the same as that carried out over the past three years during which excellent results have been obtained. 0cP/90. r Page 24 Western area includins the Extension 5.2.3. In the initia'l area, the following watercourses w'il1 be mainta'ined under 'larviciding: the Comoe downstream from the Toupe ferry, the N'zi, the Bandama, the Marahoue, the Sassandra, the Bagoe and the Baoule. The case of the White Bandama is particu'lar because although'it has been under 'larvic'iding since 1975, it was subjected to many reinvas'ions up to 1985. Th'is basin has therefore not been complete'ly decontaminated. It'is therefore wise to maintain it under'larvicid'ing, especial'ly downstream from Bema with'its tributary, the Bou. In the western extension area, the greater part of Guinea wil'l be treated. In Guinea, the N'iger basin wi'l'l be completely treated as in 1990. Larv'ic'iding wi'l'l also be extended to the upper basins of the Dion/Sankarani and of the Ml'lo. As regards Sierra Leone, since the epidem'iologica1 maps have revea'led the existence of b'linding onchocerciasis in the southern part of the country, almost the whole territory will be treated. To begin with, for lack of rainy-season larv'iciding experience, notably in the southern part of the country, it is w'ise to budget for a practica'l1y complete larviciding coverage. When the time comes, efforts wi'll be made to be as selective as possible. Larvicides 5.2.4. Considering its harm'lessness for the non-target fauna, B.t. H-14 wil'l remain the basic larvicide although it is very expensive for the Programme because of the dosage used and its low carry. It wil1 therefore be used mainly for the Iow-discharge rivers (less than 15mr/sec., as far as possible). Because of the omnipresence of resistance (or pre-resistance) to temephos or Abate in the greater part of the Programme area, this'insecticide wil'l now be used onlyfor short periods (4 to 6 consecutive cycles) and at high water, tak'ing into account its excellent carry and the fact that itis uti'lizab1e also in tri butari es. Since chlorphoxim is no longer avai'lable, it wi'll be replaced by pyrac'lofos whichis an organophosphorus compound belonging to a fami'ly different from that of Abate or chlorphoxim. So far, no cross-resistance has been observed with these 'last two insecticides. Furthermore, pyraclofos has shown an exce'llent efficacy in river with a remarkable carry similar to that of Abate. In view of its moderate impact on the non-target fauna, the Ecological Group authorized its use in the Programme area during its February 1990 meeting. Permethrin remains by far the least expensive insect'icide andits use is particu'tarly advantageous in the high-discharge rivers. However, considering its 'impact on the non-target fauna and the risks of cross-resistance with the pyrethroids used in agriculture, it wil'l be employed with caution as recommended by the Eco'logical Group. The use of carbosu'tfan, whose price is very high, will be limited. However, this insecticide shou'ld be maintained in the arsenal notab'ly for the treatment of the basins in which the b'lackf'ly popu'lations are highly resistant to the organophosphorus compounds. 0cP/90. I Page 25 In view of the considerable number of depots to be resupplied v'lth larvlcides and the considerable distances between them, the security stock should be increased significantly. As explained in the general considerations on the budget, the larvicide reserves acquired in 1989 are expected to be exhausted in 1990. The requirements for 1991 are as follows, to be financed entirely on the 1991 budget: Abate Carborsul fan Permethri n Pyraclofos B.t. H-14 83,500 40,600 60,300 71,500 371,000 I ltres I ltres I ltres 1 itres I itres AerlaI operations 5.2.5. The new aerial contract has been signed for the period 1990-1992. It is characterized by a very marked increase in costs (402). That is why the computerization and optimization of aerial larviciding become prioritles. It should be noted that thts contract has already made posstble the mountlng on the helicopters of new aerial spraying systems which have proved to be far more effective than the previous ones. l,loreover, a system installed ln the helicopters and fixed-wing aircraft, for the automatic recording of the sprayings made (ntmber of points, time, quality of the insecticide used) enables the work of the pilotsto be better monitored. According to the season, 7 to 11 helicopters ylll be used by the Prografime, while the two Turbo Thrushes will be used during the ralny season only. The number of flight hours has been estimated at 2,300 for the eastern area and 5'400 for the western area. To that should be added 350 helicopter-prospection hours per year and 300 hours for the llaison aircraft. This gives a total of 8,350 hours. EntonoloElcal eval uatlon 5.2.6. The budgetary austerity measures which were started ln 1987 have led to a considerable decrease in the VCU staff (frqn 37 professionals in 1987 to 22 in 1990, and from 504 general service staff in 1987 to 390 in 1990). No ney staff reduction can henceforth be made without jeopardizing the dependability of the entomological surveillance network. The entomological evaluation results have become an operational decislon-maklng tool, particularly concerning the resumption or temporary suspenslon of larviciding. Furthermore, after the definitlve cessation of Iarviciding, post-control studies would be necessary for at least two years. Aoolied research 5.2.7. Given the budgetary constralnts, the budget allocated to research contracts has been decreasing during ttre past few years. 0cPl90. r Page 26 This has been made possible since almost all the necessary research activities ln the extension areas have now been terminated. Besides, the VCU staff have now been suffic'iently tra'lned and prepared to carry out most of the required research activities on their own. Research contracts are now signed only with organizations which conduct research directly related to the smooth running of the larviciding operations. As for service contracts, they are devoted to hydrological data (teletransm'lssion, ma'intenance of the hydrological network) or to the obtention of the results of the aquatic envi ronmental monitoring. lbnitorins of the aouatlc envlronment 5.2.8. The monitoring of the aquatic environment will continue to be carried out accordlng to the recomnendations of the Ecological Group. In the inltial area and in the southern extension, the monltoring of the fish fauna is undertaken by the natlonal teams and that of the entomofauna by the VCU teams. The latter wi'll also participate in 1991 in the screening of new products or new insecticlde formulations. The monitoring vill be focussed mainly on the basins treated with "hard" insecticides (permethrin, carbosulfan). The introduction of pyraclofos wl'll a'lso be the subject of special studies. In the extension area, service contracts have been signed with the national teams. The study stations selected in Gulnea and Sierra Leone will be under monltoring. Servlce contracts 5.2.9. The following service contracts are proposed for 1991: US$ - Hydrobiological studies on nev larvicides - Aquatic monitoring by the national teams - l,laintenance of the hydrological stations - Contract for utilization of Argos Satellite System - Verification and finalization of hydrological forecasting models 1 0,000 93,000 38,000 40,000 1 5 ,000 TOTAL 1 96 ,000 Personnel 5.2.10, The personnel requirements for VCU, including the staff of the applied research and the environmental monitoring groups will be the same compared to I 990: - Professionals - Genera'l serv'ice staff members 22 390 TOTAL 412 Consultancv services 5.2.11. The consultancy services are related to research act'ivities in the fol low'ing f ields: GUINEA BISSAU 0cP/90. I Page 27 TOTAL - Insecticides - Hydrobiology - Hydrology - Aerial operations - Cytotaxonomy 1 month 4 months 3 months 10 months 3 months Total 21 months In add'ition, 4 short-term professiona'ls appear in the budget under "Consultants". National staff members 5.2.12. The national personnel requirements for 1991 will be as follows: POST GUINEA }IALI SENEGAL SIERRA LEONE National coord. Nat. asst. coord Entomo]ogi stll4ed. Off . Ento. techn./Nurse Nurse/EPI Vector col lector Dri ver Adm. assist. Secretary|,lech. asst. l,lechani c Radio. oper. Boatman Storekeeper Asst. storekeeper t{atchman Hydrologist Hydro. asst. 5 5 8 67 5 87 1 1 4 27 50 3 60 8 4 7 4 20 1 2 1 27 4 I 1 1 2 ,: 10 10 1 l 1 1 1 I 1 4 l I I 1 15 1 1 2 5 2 3 : 1 : 1 2 3 3 3 1 r0 3 2 6 3 1 1 1 1 3 2 4 21 13 2 1 1 1 : 1 7 2 4 1 TOTAL : 160 17 25 74 17 323 Budset 5.2.13. The proposed budget for VCU in 1991 is US $24,969,000, wh'ich represents an increase of US $9,287,000 in comparison with that of 1990. This is mainly dueto an increase in the costs of personnel services (US $1,023,000) and larvicides(US $2,020,000). Certain categories of expenditure have also increased, to a 'lesser extent, particularly aerial operations. 0cP/90. I Page 28 itSLI 6 YECI0f, CotIR0t (us t) Category of rxpcnditura RECI,RREII COSN PIRSOIIEI SERYICIS Chief YCU (l) Sciutists (l) Icchnicrl Officrrs Adrinistrrt ive Assi stants Clarls, strnogrrphcrs md 0thrr Ocncrrl Scrvicc Frsonncl Icrporrry strff Srb-totrl Consultuts Unitad tltions Yolurtmr (2) Oprrrtionrl trrvcl lcrirl oprrrtiors Contrrcts(rcscarch I othars) lrtiolrl tcus Opcrrting costs Iasccticidas Supp I ics Sub-totll IOIAL Grrde SRP sG. P5/P{ P3/P r t-l-t -t -t-r-t-l-l Itl 523 52 -t-t- t-t-r-r-l-l-l I -t -t -r -l -t - I -r - I -l 6 20 50t 5r 5t {63 t0{ {9 POSIS I - -t t{ -l-t-t -t -t -l -l -l -l -l -l - I 2 I I lr I I ls 2 5 I5 3, I r{l t90 rll I (t) Irc posts undcr contrrct lith Institut Frrnglis dc lachrchr Scirntifiqur pour lr 0avrlopplrlnt !n Coop6ration (0RSTil). (2) I Ut voluntrcr hydrologist rill be rorking in Siarrr Lronr to mintlin thc hydrologicrl nctrork r9e0 lr99ri 1916 ll 390 {t I I r2 i{r2 I i Erprnditure 1,599,513 t59,6{t 6 3, I{l , l,162, rt5 922 {lt 3t I 253 ,52I t,2ll 296 r15 15 ,35E ,9to {0 t0, I Irpend i tu ra I9il 5,t61,525 9t5t 653, 5t t 3il,900 {t2 , t{3 t5g , I05 l ,6E3, 16l 9 ,0{3, 39E -t -l -t-t -t -t -l - l -l -r -l E2 t3r 8,5{0 ,352t, {02 hpanditurc I trprnditurc t9tE I 9E9 Approvcd Proposad -l -l -l 0002{,969 -l I 990 I ,0{5,000 r99t I , 1 10,000 0, 000 682 ,500 000{t5l, 000E 300,000 I -l E2 000 000l5 000 001 tt tttttltttt 5 65 55l{t ,500 -t-l-l l-l I I ll I I I ll I 5,350,500 I 6,25t,01t I 6,{10,000 li I,193,000 i I I ll I -l-t-r r-l I 25t , I30 339, t{t 351 ,000 {05,000 25 ,000 30,000 591, t66 t50,000 1,001,216 6 , 1 00,000 509,35t {2{,231 I,112, {E2 ,661,600 32t,0t0 250, 000 15,2 l2,000 ll, {16,000 62t, I 36 5,051,321 { 6,E00,000 30E,26 I l5l , oE2 {09 203 12r {r9 23{ 33{{60 tttt il3,t5t,5t5 il3, tl Ig0,000 , goo, o0o 000 000 000 000 I90 000 { { 1 00,000 22 5,000 {, 5 I I lr I 0t t9,?ll,{05 00 I I i2 I l-l-l 20 i r9E6 i rgEr i rgEE i r9r9 tttl { r2 lt t0 tt il tt lt il ll tl 0cP/90. I Page 29 5.3. Epidemiological Evaluation Unit (EPI) us $1,754,500 Overview S.3.1. ouring 1991 the EPI activities will be centred on Ivermectin distribution in the areas at risk of onchocerca'l blindness, on intensification of distribution in western extension areas where no larviciding will be performed, on the evaluation of the areas where interruption of vector control is planned and on the selection of the new village network for post-vector control surveillance (see map in Annex IX). Distributlon of ivermectln 5.3.2. The mapping of the river basins selected for ivermectin treatment is nearing cmrpletion and during the first months of the year this activity will continue. l,lass treatment will be carried out in several river basins to protect a population of approximate'ly 400,000 people. In some locations non-governmental organizations (NGOs) will be lnvolved in the drug distribution. In all the other river basins treatment will be conducted by national teams with minimal input frqn OCP personnel. Incidence of severe adverse reactions will continue to be monitored for the required length of time. Furthermore, the effect of ivermectin treatment on the eye and skin will continue to be carefully documented to confirm the beneficia'l effect of the drug after repeated treatment. 5.3.3. In the northern part of the yestern extension area, delivery of ivermectin w'ill be expanded and accelerated. It is estimated that some 65,000 persons yill be treated in 1991 by means of active mass treatment. The zone concerned lncludes the basins of rivers Senegal, Gambia, Geba, Corubal, Upper Bafing, and all other river basins in the western extension area, west of river Konkour6. Hider criteria for selection of villages will be used, so that addltional areas will be identified for inclusion in the mass treatment programle. As elsewhere'ln the Progralrme area, mass treatment will be done by national teams under EPI supervision and, where possible, NGOs rlill be involved. Other means of lvermectin delivery will be studied in close collaboration with the national health authorities. In two rivers the effect of more than yearly ivermectin distribution on transmission w'i'l'l be studied. Interruotion of larvicidlng 5.3.4. Interruption of larviciding in several river basins of the original OCP area will be reviewed. Epidemiological information will be co]lected, analyzed and discussed for each river basin before a fina'l decision is taken. This information w'ill include not on'ly the results of the fol'low-up villages in the area but a'lso the results of several other villages selected in collaboration with the Vector Contro'l and Biostatistics and Information Systems units, to minimise the risk of missing a focal area where the reservoir of the parasite is still at a dangerous leve'|. National teams wil'l carry out this work under the supervision of OCP staff. In any of the villages evaluated a complete migration history will be taken from each person examined. 0cP/90. I Page 30 EpidemloloEical survel I lance 5.3.5. A new village network will be selected for the post-vector control surveillance aimed at detecting possible recrudescence of onchocerciasisinfection. To maximize the early warning capabil'ity of the system only first-1ine villages will be selected. Furthermore, in each focus a minimum of three villagestrill be chosen, when possible, to permit yearly evaluation while each vil'lage will be examined at a frequency of once every three years. Baseline evaluation wil'l be carried out in all the v'i'llages of the surveillance system before interrupting vector control activities. In villages where previous baseline data exist any eventual incidence case will be confirmed on the spot, and a detalled migrationhistory collected to determine if the infection had been contracted locally. HiEratlon studles 5.3.6. l,ligration studies vill be conducted to assess the importance of the phenomenon and identify the maJor sources of migration from the still infected south tovard the onchocerclasis-freed north. The level of infestation in the major sources of migration will also be investigated. EoldemioloEi cal evaluatlon 5.3.7. Evaluation of vector control actlvltles will continue ln all areas subiected to larvicidtng. This rill lnclude the southern part of the original Progralrme area, the problem spots, th€ reinvaded areas and part of the extensions. Particular attention will be given to epidemiological evaluation in the northern part of the western extension area, whlch will not be subrnitted tolarviciding and where ivermectin delivery is to be lntensified. Oohthalmologlcal eval uatlon 5.3.8. The ophthalmological evaluation will concentrate on the long-term follow up of selected villages treated with ivermectln to monitor the effect of ivermectin large scale treatment in controlltng onchocercal eye disease and inpreventing onchocercal blindness. A special evaluation effort will be made in the northern part of the western extension area. Ophthalmologlcal studles to determine the blinding potentlal of the disease in specific areas of the extensions will contlnue. Hhlle the latter work is almost terminated in the vestern extenslon it is at its beginning in the southern extension. DllA probe 5.3.9. The testlng of the Dt{A probe should be completed by the end of the current year and, if satisfactory, it will be used extensively to dlstinguish the blinding form of the parasite from the non-blinding one. This tool is indispensable ln areas where the microfilarial loads are too low to allow meaningful ophthalmological evaluation. Besides, this tool will be faster and less expensive. It will be used both in the extenslons and in the original OCP area togulde vector control measures. 0cP/90. I Page 3l Personnel 5.3.10. To carry out the above act'lvities, one Professional officer less than in 1990 will be required: - Professional medical staff members 4 - Genera'l Service staff members 23 l.loreover, provision has been made for 6 months of consultancy services for the carrylng out of a special evaluation in the northern part of the western extension. 5.3.11. In addition, an experienced epidemiologist will be hired as short-term professional, to assist natlonal officers and play a coordinating role in visiting all potential health centres for distrlbution of ivermectin, studying the local situatlon, and advising on the appropriate type of treatment to be given. He will also be expected to propose and,/or evaluate alternative distribution systems, treatment coverage, and the effect on microfilarial loads, in the short and longer term. Consultancv 5.3.12. The folloring consultancy services are proposed: - Hedical epidemiologlsts ( short-term professlonal s) 22 months Ophthalmologist 5 months Natlonal teams 5.3.13. It is expected that the following nat'ional staff members uil'l be prov'ided part-time by their governments to conduct distribution of ivermectin or epidemiologi cal eval uation: Guinea Guinea l,lal i Senegal Sierra TotalBlssau LeoneI'ledicalofficers 3 1 3 2 1 10 Technicians or 14 3 12 6 7 42 nurses Drivers836326 TOTAL 25 7 21 14 1 1 78 In addltion, six of the countries ln the initial area (Benin, Burkina Faso, C0te d'Ivoire, Ghana, Niger, Togo) will put one medical officer and seven technlcian- nurses at the disposal of the Programn. OCP vil'l bear their trave'l allowances. 0cP/90. I Page 32 National medical personnel and health centres 5.3.14. In the northern part of the western extension, besides the national teams, a network of local doctors and nurses wi'll contribute to active distribution of ivermectin 'in each treatment area. Furthermore, medical personne'l will be ca'lled upon to organize the passive distribut'ion system. A1so, fixed health centres w'il'l be involved in activities which may vary from passive treatment of indiv'idual cases who report at the centres, to active mass-treatment of the total eligible population'in the catchment area. In all these cases, OCP may be ca'lled upon to cover travel and subsistence allowances involved, as well as equipment items. Budget 5.3.15. The budget requirements for 1991 will be US $1,754,500 as compared to US $1,406,000 for 1990. The difference of US $348,500 is essentially explained by the planned intensification of ivermectin treatment campaigns as out'lined above, vh'ich vill enta'|1 the services of an additional epidemiologist, consultancy serv'ices, increased operational travel, operating costs and supplies, as well as reinforced backing of national teams and medical personnel working outside the teams. ImtE t [PI0EII0| 06tcil tvil.urllot (us t) 0cP/90. I Page 33 Crtrgory of upanditura ItcuRRilI CoSTS PtRsorrtr sERvtcts tcdicrl officln lcdi cll Off iccr-0phthrhologist lrborrtory, ttchnicrl rssistrnts ftrlcs ldriristrrtivr rssistrnt Clcrk stcaogrrphrr Clcrl ud ttpist 0rivcrs Tqorrry strff Sutstotll hnultrnts hitrd lrtiors voluntrcr (l) 0Dcrrtionrl trrYcl lerirl opcrrtions 0pcrrting costs Sugglirs hntrrcts (othcrc) lrtioarl tous (2) Sub-totrl IOIII P5/PI P.5 G.S G.S c.s 0.s G.S 8. l -l -t -t -l -t -t -t - (l) Guincr Bisslu(2) Includcs trrvcl of nttionrl mdicrl steff rorking outsido thc tcus IE 2 2 2 It {3 -l-t- POSISGredal- _ _ -li re16l rsEr i rsrEi reEei rs90i rgil itttlttt -t-t-r-l-t-t-r { t 2 lt l0 l3 3I -t -t -t -t -a {0 3I 2l 2 I 2E -t-l-l- t-t-l-t-t-t-t-r-l-t-t-t-t t-l 3 2t 2l Itrpcndituru I 9E0 -t -t -t -t -t -t -t -t -t - 500, t{t It, glt t09,t09 r63 efft0 5gr2r5 [rpanditurr I gtl 625, tt6 I1,000 Et,g9l [rpcnditurc I9EE I 5,256 I 6 fl t{ 62E, 50' EO 35 53 9 t0l 069 2t9 00{ 000 29t 3 E06 t23 {20 0{9 62 {t t3 t6rt06,0{t -l- l,101,560 l , {06 ,000 Irpanditurc l9t9 5Cg,105 03,656 5,5012 t23,ol OEE5 53E,{61 ropostdPlgproued r990 95,000 19,500 69,000 I20,0oo l0,000 l99l 309,000 t03,000 t I5,500 t-t Itt 30,000 00035 000 t3,500 000 5002l t {0,500 l-t 220,000 t5,000 500 3{,500 t90,000 ,000 ,000 tl tt il6,000 i| 2tI,00ottttttIt 110,000 100,000 l-l l-t I -t t20,000 g0,000 ,000 000 25 2t0 02I,0000006E6 ttll { { tltt tttt15:r{it3it3i tttt rttt 216 i616l lltl tttt I t l. I - r- r 1l rtttrttlttitlll-i ttltltttI i2 i313 i 5,500 tttl 3 il I I lr I 2E I I it,I5{,500 I 0cP/90. I Page 34 5.4. Biostatistics and Information Svstems Unlt (BIS) US $32Z,SOO Analvsis of eva'luation data 5.4.1. Data analysis remains one of the major activities of the unit. Integrated ana'lys'is of epidemio'logical and entomological evaluat'ion data, in support of operat'ional decision-making on where to stop larv'ic'iding, and of the entomological data on transmission levels during the flrst two years after cessation of control wil'l be of part'icu'lar importance in 1991. Analytical techniques have been developed for the rapid statlstical assessment of vectorinfectivity leve1s after return of the vector. These techniques will be implemented and'improved urhen necessary. Another important act'lvity will be the reporting of resu'lts to the statutory bodies of the Progralrme and to the scient i f i c cormun'i ty. Epidemiological model I ins 5.4.2. Epidemiological modelling will be used lntensively in the evaluation of epidemiological trends in the orig'inal OCP area, the prediction of the risk of recrudescence shou'ld larviciding be stopped, and the interpretation of post- larv'iciding transm'ission levels. The prospective appl icatton of mode'lf ing wi I I focus on surveillance and recrudescence control under devolution, and the model will be extended to allow simulation of the application of lmnunodiagnosis and treatment with a macrofi'laricide. Sensitivity analyses of the importance ofirmigration of infected persons and of recrudescence control by ivermectin will be conducted. A new ocular disease sub-model will be quantlfied and used for improvedprediction of the 'impact of morbidity control by large-scale ivermectln treatment. Deslgn and analvsis of apolied research 5.4.3. The unit wil'l assist in the des'ign and analysis of applied research, includ'ing studies on the prevention of ocular disease by ivermectin treatment and on m'icrofilaria] repopulation after treatment in order to determine the optimal dosing interval. Other activities will be ophthalmological studies to furtherdelimit the boundary of the severe blinding form of the disease, and the related study of DNA probes to differentiate the parasite strains involved. New irmunodiagnostic tools will be tested in the field to determine their potential, and new epidemiologica'l methods will be developed for the evaluation of the combination of vector control and ivermectin treatment in the extension areas. Data processing 5.4.4. The amount of data generated in the OCP has increased greatly during recent years. Special efforts have been made to ensure the timely computer processing of these data, such as priority processing of operational'ly sensitive data, and data entry by field staff and temporary staff recruited during peakperiods. These efforts wi l'l continue. A cons'iderable amount of computer prograrm'ing wi'l'l be required for the process'ing and analysis of the different data. Programming priorities for 1991 will be the provision of more user-friend'ly analys'is prograrnmes for use by staff from other units and the deve'lopment of a f lexible database system with epidemiological summary statistics for EPI v'il'lages 'in all the Participat'ing Countries. 0cP/90. I Page 35 OCP computer network 5.4.5. An important task of BIS remains the supervision, development and maintenance of the computer network which covers five operational centres of OCP, and the provision of support in the utilization of both hardware and software. The prograrmer of BIS wi'11 also assist'in the operation of the miniconputer in the Finance department. l.lany staff from the different un'its have been trained in data processing, word processing and routine analysis, and this tra'in'ing effort w'il'l cont i nue. Eouioment and software 5.4.6. A'lim'ited extension of the computer hardware ls necessary. It is plannedto purchase a PS,/2 model 80 computer for the headquarters of the western operationa'l area in Bamako to enable it to run the aerlal operations computer programmes and be compatible with its aerial base in Odienne. Three PS/2 model 50 microcomputers wil'l be procured for the central garage (spare parts management), the Documentation centre (reference and information database), and to reinforce the Insecticide Research Unit. A portable microcomputer is needed for the Eastern Operational Centre in Kara. Computer breakdowns have been very few in the past. However, many microcomputers are old and have been written off for some time now. Replacement of computer equipment will therefore be necessary to an extent during the coming year. Thegreat demands for analytical and programring support require that the available software be upgraded and extended yhere appropriate. Personnel 5.4.7. Itith the significant development of information systems in OCP, thefunctions of prograrmer-analyst must be reinforced. t{ew requirements are for the western operational area in Bamako, vehicle spare-parts management in the centralgarage in 0uagadougou with possible extension to Bamako, the conputerization of the OCP Documentation Centre, and the strengthening of the Insecticide ResearchUnit. It is planned to use the services of a short-term professional prograrmer- analyst. Thus the total staff reguirements are: - Professional staff members - General service staff members - Short-term professional The short-term professional appears in the budget under "Consultants". Budqet 5.4.8. The proposed budget for the Biostatistics and Information Systems Unit amounts to US $327,500, i.e., an increase of US $40,500 over 1990. Th'is is due tothe increase in salaries and allowances, as well as to the addition of a short- term professional to the Unit's staff. 2 2 1 0cP/90. r Page 36 IISLI E Et0sItIIsIICS AXo trmRIAIloil SySItffi (us t) POSIS lhpanditure I - -t rgEEi rsEgi r9e0i t99t i lgEE I 9E9 -r-t-t-t_t hpenditurc Approvtd r 990 Proposrd 1991 I 3,500 Catcgory of expanditurc 0rrde -t -REC|JRRETI COSIS PIRSOXXEI SIRYICES Strtisticim (Chirf) Strtisticirtt rnalyst Progrurcr rnrlyst lntlyst rssistant lfi inistrrtivr assistrnt Iuporrry msistrncr Sub-totrl Consultrnts 0prrrtionrl trrvel Contncts (othrrs) 0prrrtionrl costs Supgl ias Sub-totll IOITI P.5 P.3 ?.2 G.S G.S ,000 000 95 500 000 11,500 000 500 500 03 3 { { { t 2l 002 EE 5 tE{ 3,325 26 I03flt, 000 ,000 000 r9l 25 000 000 000 00 90 EI 50020r -l 00020 -l -l -l -l -l -t -t -tlE,55 t 2 l ,3EI 6 -t- -t- 15,ilg -r-t-t-t-t-t-l 30 2t 20,000 25 30 ,000 000 t5, 000 00 l5,000 0t5 r0l 6r3 t t t 263, 36 t 1620 236,225 002l -t-l-t-t- | -l tt ll tt il tt ll ltltl t-t-t-l-t-t-t-t-l t-t I ll ll tt il tt lt II { tt tt tt tt tt tt tl 0cP/90. I Page 37 5. 5. Socioeconomic Develooment us $142,000 5.5.1. The ma'in activities of this unit will be the collection, processing and analysis of socioeconomic data. They w'i'll also cover the role of lia'ison wlth a view to the implementation of the studies conducted under the ausplces of the Cormittee of Sponsoring Agencies and the monitoring of nationa'l studies currently being prepared. Contract 5.5.2. A contract will be signed with an institution in tlali for the collection of socioeconomic data ln the western part of the country. Personnel 5.5.3. One professional staff member and one secretary working part-time will be required for the OCP socloeconomic development activities. Budget 5.5.4. A budget of US 1112,000 is proposed for 1991, which is US g5 000 less than that of 1990. 0cP/90. I Page 38 Imtt g s0ct0tcotiltc 0tvttoPrtilI (ljs t) i Cilrgory of upcndituru lGrrdl i P0srs I l- - -r-l-l 3 -r-l-l-t-l txpcnditura i trponditu re I Erpend i ture I Approved ireE6 irerr irgrE i rsre r990 i r99r I 9tr I 9Et r 9t9 I 990 -t -l -t -t -t -t -l -t - I -l - I - I trpcnditun r9t6 05,t02 tt tt tt tg9t P roposcd t2,000 l- I I lRtc|JtRErr c0sts PtRSorxH. StRYICtS Iconorist Agro-Econorist lgro-[conori st CrrtogrrDhrr Clcrk strnogrrphr Iuporury staff P.5 P.l P.3 G.S G.S 0.5 T0 5 000 500 0000 000 000 000 03 Sub-totll 5 5 63, l16 t-t-l-t 63,lil IE,063 -t-t l-t I tl t- ll tl ltConsultants (l) 0parrtionrl trrvcl 0gcrrting costs Cortrrct (othcrs) Suggl irs {5, l0l t, 103 I I,22t t I ,561 t09 t 5 ,000 30,000 rt6 06r e 2 13,322 t2,lE5 20 ,000 t2,000 -l-t-l l-l l g, lE5 t6 ,500 32 ,000 -t-t-r r-t 000 50r 500 t-l-t Sub-totrl IOIAI. t t5 23, t62 t6,03t 13,322 -t-t -l-t -l ttt rtt I?,t09 I gl,ilE I t{1,000 i ttt 3 3 1.5 t2t,5t3 tt il il ll tt tt I I I I I I I I I I t_ I irt- I I I 10.5 I I I tt ll lt 3 3 t. tt lltt ttttlt 3 5 tltt it.5 itt 0cP/90. I Page 39 5.6. Onchocerclasis Chemotherapv Project us $1,641,500 5.6.1. The Onchocerciasis Chemotherapy Project (OCT) will continue 'lts progranme of research and development w'ith the aim of providing a safe and effective macrofilaricide for onchocerciasis. The OCT drug development programme cooperates closely w'ith the Filariasis component of the Special Prograrme for Research and Training in Tropical Diseases (TDR/FIL), whose major objective is to deve'lop a macrofilaricide for the lymphatic filariases. A conmon ant'ifilarial programme for the screening of potential drugs in laboratory models is coordinated by a Preclinical Drug Development Team (PDDT) on behalf of both Programmes. The major thrust of drug development during 1991 will be to complete preclinica'l toxicology for Ciba-Geigy compound CGI 18041 and initiate Phase I-II clinicaltria'ls in uninfected volunteers and then in infected patients. Ciba-Geigy lsgiving full support to th'is development programe and will carry out al'lpreclinical work without cost to OCP. OCT therefore needs to maintain and expand its facilities for clinical trials in endemic countries, in addition to support of ancillary actlvities such as pharmacokinetics and drug metabol ism. Facilities for contlnuing screening of novel chemical compounds for antifilarial activlty in v'itro and in vivo models will be maintained. There is increasingdifficulty in obtaining test compounds and it is proposed that some fundamental research be initiated to define new target areas for chemotherapeutic inhibitionin adult fllarial worms. As recommended by the Expert Advisory Comnittee (EAC), some funds will be allocated to develop an assay of sensitivity of microfilariae of Onchocerca volvulus to ivermectin, to enable any appearance of resistance to the drug to be monitored in human popu'lations. The spec'ific activities and resources required to carry out this prograrme are sumrarized be'low. Suoolv of test compounds to screenlns centres 5.6.2. During 1991 a major effort will be made to increase the number of conpounds submitted to screeners from industry and elsewhere. Several companies have submttted proposals to hold compounds on behalf of HHO, and ship these to individual screening laboratories under the direction of the PDDT and t{HO Secretarlat. Although a contract for th'is work has not been signed at this time,it should appear in the 1991 budget. One laboratory which resynthesizes those active compounds required for further testing has been estab'lished (Dr. D. Baker, Un'iversity of Alabama, USA), and addit'ional laboratories would be contracted for chemica'l syntheses if required. 0cPl90. I Page 40 Drug screening centres 5.6.3. Primary screening in rodent models will be carried out in two centres(Professor H. Zahner, Giessen, FRG and Dr S. Townson, St Albans, US), with secondary screening of active coumpounds being carried out either in dogs (Dr..l. !,lcCall, Georgia, USA), cats or primates (Dr J.Il. Mak, Kuala Lumpur, Halaysia). Tertiary screening against 0.gibson'i in cattle will continue as required(Professor D. Copeman, Queensland, Austra'lia). Confirmatory in vitro assays against 0. sutturosa and 0. volvu'lus adult worms yill continue to be used(Professor 0. BUttner, Hamburg, FRG and 0r S. Townson, St Albans, UK). Total screening costs will be approximately US $700,000. Clinical trials centres 5.6.4. Year-round support for the Onchocerciasis Chemotherapy Research Centre (OCRC - Dr K. Awadzi, Hohoe, Ghana) wlll continue to be provided, and other trial centres will be employed for spec'ific periods as required by successful development of clinical trials candidate compounds. Pharmacokinetic studies will usually be carried out in conjunction with clinicaltrials, particularly those at the OCRC (Professor |,1. Orme, Liverpool, UK). US 0425,000 will be allocated to such trials. Personnel 5,6.5. A professional scientist, the Project l,lanager, assisted by a secretary,yi'lI manage all activities related to the OCT. Consultancies 5.6.6. The Chairman of the PDDT is paid an annua'l sum related to expenses and time allocated to the Project (258 hours at US 950 per hour in 1990). A short-term consultant, to be employed for six months in Geneva, is being sought to establish and operate a computerized data base for drug handling and data recording. Thus, over seven months of consultancy services are required by OCT in 1991. Ooerational travel 5.6.7. US $20,000 to be used for operational travel by the Project Manager lncludes travel to OCP meetings in Ouagadougou and elsewhere, together with visits to contracted laboratories and scientific meetings. OCT meetinss 5.6.8. It is anticipated that two Steering Comnittee meetings wjll be held in 1991, usually in Geneva (total of US $60,000), together with one Scientific l{orking Group meeting on drug development (US $60,000). },leetings of the PDDT are usually held in conjunctlon with Steering Comrittee meetings and the costs of these are shared with TDR. The costs of these meetings are included in the overall estimate of US $200,000 for "consu'ltants, temporary advisers" and "operational travel " . Budget 5.6.9. A total budget of US $1,641,500 is proposed for OCT but additional funding may be needed if a promising clinical trials candidate is identified frorn secondary and tertiary screening. 0cP/90. r Page 4I ImLt r0 otflrocmclrsls cllilolllERtPY PR0JEcI (us t) POSIS I Erpanditun i hpend iturr I trplnditurc I trpend iturr I Approvld Proposcd Catrgory of uprnditure RECURREIII COSIS PERS0ilEt SERVtCt Sc irnt i st Src rctlry Sub-totll Consu ltrnts,tuporary rdv isrrs 0parrtionrl trrYcl Rescrrch (others) Othrr contrrcturl Scrvicrs 0pcrrting costs Suppl irs Iectings (l) Sub-total lter6irsEri rerrlr9r9lrseolreeti l9E6tttrrll Grrde I 9tl I 9tE l9t9 r 990 tg9t l{t,000 t2 ,5oo -t-t-t-t-t-t-l-t-l-l-l-l l-l I tt il tt il tt il tt il lt tt il lt ll ll tt ttlt P,5 G.S 000 000 28 I5 000 000 -t -t -t -l -r -l -l-l -l -r -l - lllllllllll tttttllllll i2 i2 i2 i2 i2 l2 | ilI,2il1 l{0,1931 150,6551 ll{,6331 203,000 tttlrllllll -t -t -t -l-t -r-l-t -l -l -l - 226,500 fi,00t 13,195 2, ltg , t20 gl,tgt I E, {20 I, I9l,051 50,oil 32{ 2 ,09{ g5,3ol ll,{60 9t2,39t2 60,000 l6 ,56 I tEE,262 ,000 gil ,062 il,000 t{0,000 I ,522 , ooo It0,000 20,000 200,000 t5 ,000 5 ,520 1,902 52 I |t,222 i,,,, 5 5 12, tt5 tt tt -l-t-l-t-t-t-l-t-t-l-l l-l I ttlllllllll tttltlllllli i i i | | 2,93t,630 i 2,t61,05t i 1,95{,161 I .l,029,135 i1,110,000 itltttllllll -l-t -t -t-l-t -l-l-l -r -l tttttttllllltttttlllll 2 i 2 i 2 i 2 i 2 i 2 i 3,050,9fl | 2,601,21t | 2,105,116 I l,llt,36E 11,919,000 | rtrtltttlll -l-r -t -t -t -t -t -l-r -r-l (l) Costs of rcctings rn included undcr 'Conrultrntl,tcrporrry rdvisars'rnd '09rrrtionrl trrvcl' IOIII ttlt |1,il5,000 Ittl-ltttl lt,6{t,500 I tl t-t tl il ll tt lt lr il tt 0cPl90. r Page 42 5.7. Administration and Supoort Services Unlt US ie,695,500 5.7.1. The Administration and Support Services Unit will continue to p'lay its role in severa'l fields: (a) supporting the technical and operational units through an appropriate management of personnel, finances, equipnent and transport; (b) seeing to the monitoring and improvement of administration in the whole Prograrme area; (c) seeing to it that financial rules and procedures are strictly respected, that instructions are kept-up-to-date and exercising a continuous control over expsnditures and cormitments (assisted by data processing); (d) contributing to the improvement of cost-effectiveness, the application of basic management principles, and good management i n genera'l . 5.7.2. Accordingly, management seminars, one for the inltial area and the otherfor the western extension, will be organized in 1991, as yas the case in 1990.Efforts will be made so that the seminars, through the new ideas produced and thefollor-up of the conclusions and recormendations, wlII be increasingly fruitful. Personnel 5.7.3. The staff requirements for the administrative and managerial duties will remain the same as conpared to 1990: - Professionals - General service staff Consultants 5.7.4. A short-term professional, whose activities cqrmenced in 1990, will have the duty of continuously providing the necessary support and guidance to the national coordinators, their deputies, administrative assistants and the other staff concerned in the western extension, so as to he'lp them have control overtheir administrative and managerial duties, notably in the financial field. Budset 5.7.5. The budget for 1991 represents an increase of US $268,500 compared to 1990. This amount is explained by the increase in the cost of personne'l services and the addition of a short-term professional. 8 88 0cP/90. I Page 43 IABII II IOTITISIRTIIOll TTO SUPPOf,I SERVICIS (ljs t) POSIS 0rrdr reE6lreErirssrir9Eeireeoiregli leE6 i trpend i tu rc i trpcnd i turr I hpcnd iture I tlpsndituru | Approvad Proposcd Cltrgory of srpcnditurc RECURRITI COSIS PIRSOIXIL SIRYICES Chirf ldrinistrrtion t lrnrgcrcnt ldrinistrution Officcr Parsonml 0fficrr ludgct rnd Finrnca Officcr ldrinistmtive Officcr Irrnsportrtion I Cor. 0fficer Supply ud $niccs 0fficcr Supply 0fficcr Finrncl 0fficcr lfu in i strrt iYe 0f f icar/luilo Prrsonncl Officrr lilinistrrtivc md Icchnicrl rssistrnts Clcrls ud tlpists t stonkepr Oriran, rcssangcrs md Iuporrry staff Sub-totrl Consultrnts Opcrrtionrl trrvcl Srruica contrrcts Opcrrtionrl costs Suppl ics Sub-totrl I0Iil. IgEI I9m 35,652 t2E,892 r 9t9 I 990 t99 r t 03,000 103,000 tttttt -l-l-l-l-l-l-t-t-t-t-t t-l il tt il lt il tt tt il .0 .5 .{ .{ ,l .t .t .3 .3 .3 .2 000 000 000 000 g5 g5 95 g5 g5 l6 t ,000 529 ,0oo 322 ,000 30,000 r30 3t5 il5 ,000 ,000 ,000 ,000 000 000 r03 r03 2 103,000 I 2 22 It tt I 2 23 l9 93 r.s t9 t2 30 IO, IO, IO, II,500 Il ,500 II ,500 It9,000 02 t ,000 31 E,000 30,000 0.s G.S 0.s 20 t5 3t l{ {6 2E t{ tc 2t -l-t-l-t_t -l-l 1 ,121 ,000 -l-l-l-l-l-l-l-l-l-t l-l 53, l12 ret il5 t0I g6 g6 3{ t-l-t- rtE,3 1 t ,965,500 I I Ii ?20,000 I | -l tl tt 12,685,500 | tt 3 16,9il 6l, l{t ll, t5t 3t5, tt5 20{,350 6l,ll3 I |E,32 I ?l,313 333 ,932 t09,510 000 000 000 0090 55,000 I 30,000 35,000 350,000 t50,000 253,66 I 156,{63 3{5 ,5EE 129,939 -t-t-t-t-t-t_ 50{,631 692, IIt 6{0,01 1 6t6, t31 -l-l-r-t-t_t_t_ -t-t-t-l 2, {l?,000 -l-l-l-l-l-r-t-t-t-t t l l0t lI5 t0t g0 g6 0090,,2 tg3,2122 I20t2 lltt 1,0il,619 | 1,630,35t I ll tttt 1,615,312 | 1,5C0,il5 |tt lt ll tt ll ll OI 0cP/90. I Page 44 IABLE I2 AO]IIIIISTRITIOil TilO SUPPORT SERVICES SUII!|ARY BY CIIECORY OF ETPEIIDITIJRE A}IO 8Y SECIIO}I (lJs t) Sect i ons Adri ni strrt i ve j Budget t F i nance 302 ,000 55 ,000 I 5 ,000 5 ,000 7 ,000 ldr Barako -t-t- 0501 T llana rt sport ge!ent nePcrson S ,l 0002tI upp TOTAL Category of Expend i ture llrnrgerent EgrY I CeS t- RECURREIIT COSIS Personnel serviccs Consul trnts Operational trrvel Scrvicc contrrcte 0pcrrting costs Srppl ics IOTTL l-l il6,500 t 5 ,000 t 32 ,500 5 ,000 00003 229 ,000 I 0 ,000 01 500 20 ,000 65 ,000 2{0,000 35, 000 000 ,000 0002 05, t5,000 95 ,000 t-t-l 381, 000 2il,000 1,110,500 77,500 -l-t-t-l- t- 00008 000320 2 ,685 , 500 I t- I I I I I I i 1 ,965,500 I I i 55,000 I I i I 30 ,000 I I| 35,000 I Ii 350,000 I I i t 50 ,000 I 0cP/90. I Page 45 5.8. Administrative suoport in Geneva us $34o,ooo 5.8.1. t{HO Headquarters wlll contlnue to provide administrative suppont to the Programme in a series of indispensable fields whlch cahnot be covered in Ouagadougou: salaries, allowances, pension and insurance, personnel administratlon, medical services, central procurement of supplies and equipment. 5.8.2. For these services, WHO is authorlzed to charge OCP 13x of the budget of the Programme (since it is a programme supported from extra-budgetary sources). This would have meant, for OCP, an amount of US $4,466,150 to be paid. However, WHO Headquarters charges OCP on a cost recoverable basis, i.e., an amount of approximately US $340,000. TABLE 13 TDIIIIIISIRATIVE SUPPORT GEIIEYA(us $) Glcricrl rssirtance Finance, Personnel Supply 0perating cost Suppl ics I 986 { r 987 200,000 25,000 003 003229 700226 r 988 I 989 r 990 t99t t-r-a-t t- t96,{0, t-t-t-!- t5,000 35,700 35,000 l-t t- 269, I00 -t-t_t_t 62 t3 29 ,000 0005 0003{0 0 000290 -l 0 0003t0 30 t3 ,000 000 35 ,0 5 00 00 TOTAL 2820 68825 ,000 8r3 20 2t llote Adrinistrative support is provided by IllO headquarters in Geneva in the areas of personnel adtinistrrtion, budgct, finance, insurance and supply services. -t I I I I I I I I I I t I I I I I I I I I a I I I I I ItltltttItttttttlttttt la at I I I I I I I I I , I 0cP/90. I Page 46 5.9. Statutorv meetinqs US $3OS,OO0 5.9. 1. The meetings p'lanned for 1991 are: the Ecolog'ica'l Group; the Expert Advisory Committee; three sessions of the Conmittee of Sponsorlng Agencies; the Joint Programne Ccnmittee. The budgetary provision assi stance, translation supp'l ies. One ful'l-time budgeted for within the of meetings. covers the costs of trave'l and per diem, temporary of documents, interpretation servlces and various administrat'ive off icer and a secretary working part-time,Office of the Director, are employed for the organization 5.9.2. The National Onchocerciasis Comrittees hold an annual technical meeting of national experts under the coordination of the Progranme Director. The 199.| meeting rill be held in Ouagadougou. 0n1y the costs of the secretariat andinterpretation services have been budgeted for this meeting. Although, technically, this meeting is not a statutory meeting, its costs are reflected under this programme activity. 5.9.3. The costs of the participation of non-OCP experts ln OCP meetings other than the above, related to research, ivermectin dlstribution, hydrology or hydrobiology, modelling, etc., have been lncluded in the "operational travel" category of the budgets of the host units. Budoet 5.9.4. The budget proposed for this programme activity is estimated at US $305,000, i.€., the same as that approved for 1990. 0cP/90. r Page 47 TABLE II STAIUTORY IIEETIIIGS (ljs t) Expend i ture r 986 Expend i ture r 987 Category of cxpenditure Expendi ture I 988 Expend i ture I 989 ovedppt r 990 oposedP r99r RECURRE}IT COSTS PERSO}IIIEL SERVICES Ierporrry assistance Sub-total Consultrnts/Iorporrry rdvisers Opcrutionrl travel 0perating costs Contrrcts/Irrnsl ati on Suppl ics 63,311 -t- I I 63,3{{ i t6,676 I -t- 206 I 38,696 92, t6{ 39,028 -t- I I 39,628 i 29,81{ I -t- I616,6 tI29 t5 00015 {5 ,000 t5,000 ,812 58r 29r 8r9 t2t 81 122 I I 89,768 t35,585 1 35,000 1t0,000 00 000 135,0 0 0,581 3 ,962 29 il0,000 5 ,0006 2 -t- I 20t02 5 70 5 5 8 38 -t-l 260 ,000 5 68 6 I00 82 {3 2 000 000 Sub-totrl 22 5I 2li,l5l 2 2 0 00030 260 ,000 I(}IAL 290,759 286,881 -t- 250,779 -t- t-l 000305 -t-t- ,000 l-t I t-t 0cP/90. I Page 48 6.10. Capltal costs Offlce equlment us $949,500 5.10,1. This mainly concerns furniture. Only replacement furniture will be bought. The cost remains the same compared to 1990, i.e., US $25,000. Data orocessins equiment 5.10.2. The computerlzation of the organization is being pursued as regards the operations as well as administration and management. Five centres have been provided with computers: Ouagadougou, Bamako, Odienne, Bouake and Kara, and portable computers are also belng used. A limited extension of computer equipment is necessary. It is planned to buy a PS,/2 model 80 computer for the headquarters of the western operational area in Bamako for the processing of programes related to aerial operations in liaison with the Odlenne aerial base. Three PS/2 model 50 micro computers will be boughtfor the garage in Ouagadougou (spare parts management), the Oocumentatlon centre in Ouagadougou vhlch will be computerlzed, and the strengthenlng of the Insecticide Research Unit in Bouake. Furthermore, a portable micro-computer and the replacement of old equipnent are necessary. The total amount required is US $54,500, i.8., an lncrease of US 119,500 compared to the 1990 budget. Technlcal equipment 5.10.3. This concerns the purchase, installatlon, replacement or maintenance of various items: hydrology (beacons, water-gauges, batteries, solar panels), generators, research (mini-gutters, susceptibitlty tests, optics). An expenditure of US $210,000 ls envisaged, i.€., a decrease of US $90,000 ccrnpared to 1990. Vehlcles 5.10.4. A complete review of the vehicle fleet has been made to verify, on the one hand, the state of and, on the other hand, the need for each of the 348 Programre vehicles, i.e.,218 for the inltial area and 130 for the western extension. It will be possible to reduce thls number gradually to 336. The progranme for the replacement of old vehicles, however, must continue unabated. An amount equal to that of 1990, i.€., US 1650,000, will be needed in 1991. See in Annex X the evolution of the number of Programe vehicles from 1981 to 1991. Bui ldlnEs 5.10.5. No new building will be constructed in 1991. It is lntended to complete the 1990 construction prograrme. An amount of US $10,000 (US $75,000 in 1990) is required for the improvement of the infrastructures. 0cP/90. r Page 49 IABLE I 5 CAPIIAL COSTS (us t) E xpend i ture I 986 Expend i ture r 987 68,3t9 Expendi ture I 988 Expendi ture 1989 I 990 -t- Approved 25, Proposed t- 000Office furniture (l) Oata processing equiprent ( I ) Yehicles Equi prcnt 8ui lding 53,91 I 1175,9 {t I 000 000 2 r 991 5{,50058,811 35, 3{1,218 {2t,290 t8t,63 I l,ll0,3l7 7 3,925 193,995 t83,t27 32,502 111,213 t9l,03t 23 ,030 650 ,000 300 ,000 75 ,000 650,000 210,000 I 0 ,000 ALTOI -t- I ,058,509 I ,085 ,000 -t-t-l-l- 6I It t- 92I,767,I I 68I 50t9 0 (l) During 1986 to 1988, the acquisitions of drtr processing equiprent rere chrrgcd to Office Furniture IABLE I 6 BREATOfiil OF CAPIIAL COSTS IO ACIIVIIIES (us t) 0ffice 0ata process i ng equiprcnt Uchicle 300,000 5{ ,500 000 000 50 ,000 -t- -t- 65 t 0 ,000 prentEqu ngdBu -l 0000 TOIAL tureurniF -t- Progrure Director Ycctor Control Epi dcri ol ogicrl Evrl urt i on Biostatistics and Inforration systcrs Soc i oeconoai c dcvel oprcnt Adrinistrrtion and rupport Scrvices r 000 10,000 { 20 ,500 ,000 ,000 ,500 2500 ; 5 6 500 000 000 500 500 000 tl 000 000 t5 5{5000 2000 5 0 7000 0002 02 3 t- 0 000 0 919,500IOIA 25,000 -l-r-r t-l- t- l- 1 00 ,000 5 2 2 I t 2 ?86iF lrl<oEFtsE2oZL =3oo oz l! G, J =I4 o x UI z G, llJtFf oo trlE z alrlFo ut U' U'g o G,lrl(, o -oz o EA A El|l - o =UJ -o l! -oEE :JEf,oz? E5 85oH 6 9F -z 9H8t EI oY- sd =sI +d E TBo =<E 3B zI U'z trJFxlrl zc lrJFo llr ' t oFo ut Eo ul = =Eoo tr. o. o =oa{zb<? 9; ?6 ;= oaE -P = UJIlrlr<o> - ltl ::|ll =(,f 6-E9OEJ<oa =irrl>Ql{1lrl lrlG =I .E o ITE -Glrl g, ut = oEF2 oo c,o (, arl 0cP/90. r Page 50 ANI{EX I o o o ocf? o I,J T 5Ho6 -o zI F c, ocoz E z 9F =J o lrlo ct = = .EF o a, =!rlrl = z o F -lrl - =ooa z o - aoIL = lrJoz z E oz F arl(, alo lr, - -oo3 ulA z 9 3 o 2 = o G, lrt 9. o0 oF Ig F<a,Zu =;G, Ifoov, l! F ot! ru! FI ouJ(,E o -o Jod <ZEE9sUJF- E, ulG o 9- euitEc o. ul)oo oY =a ,o0Doo a Do UJ = = E,ot.rFiFE, .IdoEJ 2z 8F -u, N P6 B5 o - I C)z o ZO E< -[o 2 lr, o <urt2EOlrl u -ut J u,t =(, <= uJ<zo =0 ot.o o IJz ul U' -FJO < lrl == JU' EUJ C)azq9 esOJF<2>lrJ lrl a,zo -llli=2ETI!ITACl<oo Et{o E -lrt9 69F s 0cP/90. r Page 5I AI.II{EX II IoGtrtrG E'i e8 AEoo alro9orE 9.EE F botr6 E T F'FI ---Y:oc EE Elr.o9 tox o(ooNoooooooF F oN F o G, F ot F olo F o(o F L. o o L Gt,trg Go o o) o) o @o F @ @ o) F No o, F @ @ o) F lo @o F rfo o) F (D @ o) F N @ o, F F. oo F E, JJoO L^f,no3o lJI ] -I l-:-oF15 lloo5 UPz=<')IOOarX... IJJ O lt o_og U' IJJF E, aleJ a6ueqcxe 1861 1o e6eluecred 0cP/90. I Page 52 ANIIEX I I I Staff Professional 02 P6 - P4 Ouagadougou Geneva P3-Pl General Service - others General Service/OCP Geneva Consu 1tant,/month Temporary General Service/month Note Aerial Operations Cost per flvins hour (incl fue'l) Guaranteed hellcopter hours Excess hel icopter hours Guaranteed fixed-ring aircraft hours Excess fixed-wing aircraft hours Guaranteed Liaison aircraft hours Excess liaison aircraft hours Insect i ci des AVERAGE COSTS USED FOR BUDGETARY CALCULATIOT{S 1 989 US$ I 74 7 100 90 112 65 000 000 000 000 000 000 000 600 1989 USI 631 ,510 647 536 189 104 I 989 us$ 3.90 15. 35 11.00 11.20 19. 40 105 95 128 70 11 75 7 113 103 144 77 13 82 7 000 000 000 500 500 500 700 900 1 990 US$ 000 000 000 000 500 000 000 800 I 991 US$ The above estimates include gross salaries, post adjustments, allowances and grants, OCP's shares of pension plan (15I) and medical insurance(2.52) per diem for consultants, medical evacuations, any other emoluments provided for in the staff rules. B.LH-l4 Temephos 203 EC Chlorphoxim Permethrin 20t EC Carbosulfan 25t EC Pyraclofos 50I EC per I itre per 1 ltre per I itre per l itre per I itre per I itre 1990 US$ 853 742 869 758 248 124 Cost (CIF) 1 990 us0 3. 50 12. 60 r1.20 19. 40 25.00 .76 .75 .638 .99 .20 1991 us$ 853 742 869 758 248 124 1991 us$ 4.81 11 .96 9. 05 21.75 27.14 Value of US dollar CFA Franc French Franc Swlss Franc Pound Sterling 0eutschmark Canadian Dollar Japanese Yen Budqet 89 Budqet 90 Budqet 91 .71 287 5 1 0 1 1 125 .43 .538 .70 .23 338 6 1 0 1 1 285 5 1 0 1 1 .68 .47 .600 .68 .18 11 40 49 0cP/90. I Page 53 At{t{Ex Iv NI'I,IBER AND PERCENTAGE OF OCP STAFF MEMBERS BY SEX AND NATIONALTTY As at 31- May 1990 PROFESSIONAI,S GENER,AL SERVTCES NATTONALITY MaIe FemaIe t Total MaIe FemaIe TotaI I Total AI,GERIA AUSTRALIA BEI,GIT]I{ BENTN BURKTNA CONGO COTE D'IVOIRE FRANCE FED. REP. OF GER. GAIITBIA GHANA ITALY MADAGASCAR MALT NETHERI,ANDS NTGER SENEGAL SWITZERI,AND TOGO UNITED KINGDOM USA 0 0 2 1 6 1 2 3 1 1 5 1 L 4 L 0 2 1 3 3 2 0 0 o 0 0 0 0 0 o 0 0. 0 l_ 0 0 0 0 0 o 0 1 o 0 2 1 6 l_ 2 3 1 1 5 1 0 4 1 0 2 1 3 3 1 0. 00 o. 00 5. O0 2.50 15.00 2.50 5. O0 7.50 2.50 2.50 12.50 2.50 2.50 r.0. o0 2.50 0.00 5.00 2.50 7.50 7.50 5. 00 0 0 0 53 L40 o 91 t o 0 63 0 o 66 0 7 0 l_ 55 0 0 L61 0 93 0 0 59 2 o 0.20 0.20 0. 00 10. 39 3L.56 0. 00 L8 .24 0.39 0. 00 0. 00 L2.55 0. 00 0. 00 t3.53 0. 00 L.37 0. 00 0. 20 10.98 0.39 0. 00 L L 0 0 1 t- 0 53 2L o 2 L 0 0 L 0 0 3 0 0 0 o o 2 o 2 0 0 64 0 7 o 1 56 TOTAL I ggl z I aolroo.oolazal n lsrolroo-oo 0cP/90. r Page 54 AT{NEX V Loq3E FOE 8-E FO o o)o o, F. (r) Ntlo N- q o F otlo o @ o @ c, @ T\ q (o o ct o, q N o) o; +,o oo o J oL o o+,o o o. rts o Lr ott E Jz F o) o) F oF F CI' o) F =oEIL J]UzzooElll o- Eo F @ oo q o N\tto @ o = o oc : E E o o o o o og o o o ctr o o o o- I o o oo o o o 3t G oc og o o& E =z o o oo (g cg o o o o L o. o o .o E =z ffi @oo F No o) l- (o @ o) F lo @ o) F + @ o)F (t, @ o, F N @ o) F F @ o) F o C{o$o(o N ro oo F Il, |o lr) u) lo G, @ ?(o (o to N 1.) N(o oN F. lo No @(o TE o @]\ N c; q lo (o d ot F o @ F o c) F oo(\t o anlE^ l86I lo aoeluocrad , 0cP/90. I Page 55 ANI{EX VI @ U'f Oh!oro o): ==IL?btr:sS-,,ooFO IN L TU o L oE'tr -9o() o) o) ooo o @o F o @ o) F N @o F (o @o F to @ o) $ @ o) F (Y) 6 o) F (\t @ o, F F @o l- F c, ,F G, F o t G, I c, \ G, oo @lo 1.) to @(o NN N oooN ooN G,oN o) @ot\ (ot @ T\ o @to o c, @ lo a) o lo (o t e 1.) q @ @ F o o) F oF F @o - Oto =u,oaEb o@=z9o; - Sl-o, E UJ o-o J E UJ o ot o$o(oo@oo F oN F oto(oo@ ?- oo st o anle^ t 86 t lo a6PluacJad zI a L I a E a e. lI U (, z aE/ t i g J ) (. E I x:SEE5 E EE E5 oo. oEitrf, or9 'oE; Et fiib= oE :9 *E pE t;; o -.= L BE :Ee !'3lLJ 5< (rO.i:lr:to ;,(,l zl ,\ al \ ('r: )r\/(t\l 0cPl90.I 5, Pase55@f ,j ANNEX VIT'' "]I o o (r f, o 0- l! o o(L otr(L f,() UJo U' z o F oal-{ LuHg HtuJz zj x YE z otL v,zo F (ts lrJ(L o tto z J o- f,o olrj @ oG o(r(L l. I i t t 0cP/90. I Page 57 A]{]{EX VIII VCU ENTfiOLOGICAL EVALUATION NETHORK - 1991 Western ooerational area WOA - Bamako. tlali Sector Bobo-Dioulasso (*) INITIAL AREA Countrv Burkina Faso and l{al i (l,l) COte d'Ivoire 1.lal i TESTERi{ EXTETISIOil Countrv Guinea Hal i Senegal Slerra Leone Bouake (*) (Supervision, HQ WOA) Bamako Sub-sector Sikasso (l'l) Bandiagara (l,l)(temporary) Korhogo Odienne Seguela Ooerational baseSector Kankan Faranah Labe Bamako Tambacounda Hakeni Kankan Si gul ri Beyla Kerouane Kissidougou Dabol a Kouroussa Faranah Labe Hamou Gaoual Bamako Kita Bafoul abe Kenieba Tambacounda Kedougou l,lakenl Kabala Bo Gabu 1 2 3 4 5 6 7 8 9 0 I 2 3 4 5 6 7 I 1 1 I 1 1 I 1 18. 19. 20. 21.Guinea Bissau Gabu a I 0cP/90. I Page 58 ANNEX VIII (cont'd) Eastern operational area EOA - Kara. Toqo INITIAL AREA + SOUTHERN EXTENSION Countrv Sector Burk'ina-Faso (Supervi(SuPervi sion, Bobo-Dlasso)sion, HQ Ouaga) SuFsector Bobo-Dioul asso Ouagadougou C0te d'Ivoire (Supervision Bouake) Bouake Bondoukou Togo Kara Kara Atakpame Ben'in Parakou Parakou Bohicon Kandi Natiti ngou Ghana Tamale Tama'le Kintampo Hohoe Bol gatanga Ni ger (Supervi sion, Parakou) Niamey (*) ls a result of the new delimitation of areas, the sectors of Bobo-Dloulasso and Bouake remain in the l{estern Area but their sub-sectors have been shared between the West and the East. a , oa a J t a ao t , o I o /. I o b ! ! tr (, o E o ,; tr C, E o o o!t o o I'S ElJ| E8 :9b Yol!E oiE .lr- LCoE -o (,ootr :E'3r, > N E ! o o!t I r, I 8 Gl o e o 0cP/90. r Page 59 AI{]{EX IX U, I vtgE E-exboL G/t cDo,gE o.9 EEgJ =\t-> Jor.! >! E8E|aJCoo .oa o-EoiOLJ tilrII + + t , oE2oI , o 6Fo(, s I \:\\ fo t oIt t o @ o $(r t \l ,s Y o , E fi .a \ I t I I I I t i8i sg l, I t tn a E (\ t st t--l f a6 O I ) I t\ \ lrl E -l( - z I , I I I I I t t{r (D t $ $' I I I \ I I t \ \ I\ I t 't I I I I I I I , I -t- q\ + \ q (D!b vt \ $, 1 zF(J lrJ ==Ittr n!(ts -.UJJ fur Hu -rE ,,, =oFFzzlrj uJ ==F l^, EEFF 3x TH z -O)Fo() Hrin 0i lrJlrJ EI(L =u,n22ooNN H llJx lrJ zz x lrl z z lrJf, o tr lL I(r lJ- + , t ? \ a at a a 0cP/90. I Page 50 ANNEX X f (o C, G, L o o L ot,trg o() F o,o F oo o) F o) @o F @ @o F N @ o) F (o @o F lO GOo F t @g) F (r) @o F N @ o) F F @o F N ro N N N cl o T\N NoN o ,F(, rfN(, o rf c, @t c, @ 1l) e) F oo F oF F o o) F =o E,lr zIF E, IJJGo =qt ltJJo I - I ul aI olooo F o ro F oo ot o toN oo(D G, c, c, o to G' ootf salclqen lo raqunN I o t