Case T-226/18: Judgment of the General Court of 30 June 2021 — Global Silicones Council and Others v Commission (REACH — Updating of Annex XVII to Regulation (EC) No 1907/2006 concerning restrictions on the manufacture, placing on the market and use of certain dangerous substances, mixtures and articles — Restrictions concerning octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5) — Manifest error of assessment — Annex XIII to Regulation No 1907/2006 — Weight-of-evidence determination — Article 68 of Regulation No 1907/2006 — Unacceptable risk — Proportionality — Essential procedural requirements)