Judgment of the Court (First Chamber) of 6 May 2021.#Bayer CropScience AG and Bayer AG v European Commission.#Appeal – Regulation (EC) No 1107/2009 – Articles 4 and 21 – Criteria for approval – Review of approval – Plant protection products – Implementing Regulation (EU) No 485/2013 – Active substances clothianidin and imidacloprid – Seeds treated with plant protection products containing those active substances – Prohibition of non-professional use – Precautionary principle.#Case C-499/18 P.