Plan of action and budget for 1992

Onchocerciasis Control Programme in West Africa Prograrune de Lutte contre 'l'Qnchocercose en Afrique de l'Quest ] JOINT PROGRAMME COI,IMITTEE Office of the Chalrman JOINT PROGRAI.{ME CO},IMITTEE Twelfth session Rivadh. 1-4 December 1991 Provisional aoenda item 9 .CO}.IITE CONJOINT DU PROGRA},I},IE Bureau du Pr6sident JPC12.4(ocPle1. 1 ) Ori gi na] : ENGLISH September 1991 JPC-CCP PLAN OF ACTION AND BUDGET FOR 1992 II ONCHOCERCIASIS CONTROL PROGRAM},IE IN }'EST AFRICA II. III. IV. v. VI. VII. VIII. IX. x. ocP/91.1 PLAN OF ACTION AND BUDGET FOR 1992 TABLE OF CONTEI{TS RATES OF EXCHANGE OF THE US DOLLAR 1982-1991.. AVERAGE COSTS USED FOR BUDGETARY CALCULATIONS.. NUI,IBER AND PERCENTAGE OF OCP STAFF },IEHBERS BY NATIONALITY AND SEX AS AT 31 }IAY 1991. COST OF PERSONNEL FROH 1982 TO 1992. AERIAL OPERATIONS FRO},I 1982 TO 1992. ilAP - PROPOSED VCU PLAN OF OPERATIONS FOR 1992. VCU ENTOilOLOGICAL EVALUATIOT{ NETI{ORK - 1992 },IAP - IVER},IECTIN LARGE-SCALE TREATHENT PLAN FOR 1992. VEHICLES IN OPERATION FROI,I 1982 TO 1992. I 2 3 4 5 INTRODUCTION.. Paqe 3 5 7 I 19 19 50 51 52 53 54 55 56 57 59 60 OVERVIEW OF THE PLAN OF ACTION. PLAN FOR IVERHECTIN TREATI,IENT... GENERAL CONSIDERATIONS ON THE PROPOSED BUDGET FOR 1992. ESTI},IATED COST BY PROGRAMI,IE ACTIVITY. Vector Control Unit. Epidemiological Evaluation Unlt. 25 Biostatistics and Information Systems Unlt. 30 Devolution Unit. Onchocerclasis Chemotherapy Proiect. . . Offlce of the Dlrector. Administration and Support Servlces Unlt. Administrative support in Geneva Statutory meetings. Capital Costs. ANNEXES I. OCP ORGANIZATIONAL CHART 5.1. 5.4. 5.2. 5.3. 5. 5. 5.6. 5.7. 5.8. 5.9. 5.10. 33 36 40 42 41 46 48 a ocP/91 .1 Page 2 TABLE 1 TABLE 2 TABLE 3 TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE TABLE LIST OF TABLES BUOGET BY PROGRAMME ACTIVITY.. BUDGET BY CATEGORY OF EXPENDITURE... BUDGET FOR 1992 - SUH},IARY BY PROGRAH}.IE ACTIVITY AND BY CATEGORY OF EXPENDITURE.. VECTOR CONTROL. EPIDEHIOLOGICAL EVALUATION. . . . BIOSTATISTICS AND INFORI,IATION SYSTE}1S. . . . DEVoLUrION.... ONCHOCERCIASIS CHEI.IOTHERAPY PROJECT. . . OFFICE OF THE DIRECTOR. ADN,IINISTRATION AND SUPPORT SERVICES. . . . ADI.IINISTRATIVE SUPPORT GENEVA ADMINISTRATIVE COSTS - CONSOLIDATED TABLE. STATUTORY },IEETINGS. CAPITAL COSTS. BREAKDOWN OF CAPITAL COSTS TO ACTIVITIES. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Page 14 16 18 24 29 32 35 39 41 43 44 45 47 49 49 0cP/91 . I Page 3 1. INTROT'I'CTIOT{ 1.1. The Plan of Action and Budget for 1992 falls within the framework of the Plan of operations for the Fourth Financial Phase (1992-1997) which is in conformity with the Long-Term Strategy. A draft gf the Plan of Operations was presented to the eleventh session of the JPC' (Conakry, 3-6 December 1990). The final version is to be submitted to the present session for approval. 1.2. iJhile carrying out its ongoing vector control, epidemiological evaluation and ivermectin distribution activities, OCtr is increasingly focusing on devolutior, i.e., the taking over by the Participatlng Countries of residual onchocercias'is control activit'les, integrating them into the national health systems, using mainly epldemiological surveillance as well as 'ivermectin treatment. The seven Participating Countries in the initial Prograrrne area have nort prepared their devolution plans. After Burkina Faso, l.{aii and Niger whose p'lans were presented to and approved by the JPC in 1988 and 1989, the JCP approved the plans presented by Benln, C0te d'Ivoire, Ghana and Togo at its eleventh session. 1.3 Devolution w'il'l constitute one of the main actlvities of OCP throughout the fourth financial phase. To that end, a structure has already been put in place in the organization, in the form of a Devolutlon unit, thereby meeting a recoomendation made by the OCP External Review in its report of October 1990, endorsed by the JPC at its eleventh session. The unit is charged with themany aspects of OCP's work concernlng devolution. It will rork in close cooperation with the Participating Countries and the t{}l0 Regional Office for Africa (WHO/AFRO), which has appointed a Devolutlon Coordinator based in Ouagadougou. A Devolution Task Force has been established, composed of the WHO/AFR0 Regional Advisor.on Parasitic Diseases, the Devolution Coordinator, a representative of OCCGE{, and OCP. 1.4. It witl be noted that the staffing requirements of the Devolution unit have been met through the redeployment of existing posts representing the spectrum of entomological, epidemiological, socio-economic development and information activities. No additional post has therefore been created. 1.5. Socioeconomic development activities are notr carried out ln the Devolution unit. Essent'ia'lly, OCP provides I iaison services with the Comnittee of Sponsoring Agencies and the Participating Countries. Furthermore, OCP has contributed to the analysis of a series of regional and country development studies in the Programe area, completed by the Cormittee of Sponsoring Agencies. These studies were aimed at identifying' in | .tpc: Joint Prograrme Cornnittee 2 ocpt onchocerciasis Control Prograrme 3 OCCCE, "Organisation de Coordination et de Coop6ration pour la Iutte contre les grandes End6mles"(Organization for Coordination and Cooperation in the Control of the l,lajor Endemic Diseases) /e0cP I 4Page I onchocerciasis-freed zones, the most promising geographlc areas for agro- pastora'l production, and at drawing attention to settlement issues and policy options. Socioeconomic development activities are bound to galn momentum with the progress of onchocerciasis control.OCP's precise role in the iight of this intensified effort is still to be defined. 1.6. In the initial Prograrme area, larviciding now concerns only the zones which had been periodically reinvaded before the southern and western extensions were established. Since the start of larvicide applications in these extensions, the problem of reinvasion has disappeared for the third consecutive year. The cost-effectiveness of the aerlal operations has markedly improved, partly by the extension to the whole Programme area of computer'lzation and optimization of larviciding, and partly by the development of new helicopter-mounted spraylng systems that are far more effective and reliable than the previous ones. 1.7 . Special attention is paid to the strenghening of ivermectin distribution in the whole Progranrne area particularly ln the zones at risk of onchocercal blindness. The efficacy and safety of the drug favour its acceptance and allow a satisfactory coverage. To increase the distribution further, wider criteria for the selection of villages to be treated will be used and efforts will be intensified with a view to passive dlstribution in the fixed health centres. Emphasis will also be laid on education and public awareness campaigns. For all these activities, an lncreasing use of nationals of the Participating Countries worklng under the supervlslon of OCP staff will be made. 1.8. Through the new joint "tlacrofil" Project, the Onchocerciasis Chemotherapy ProJect (OCT), in collaboratlon with the Speclal Prograrme for Research and Training ln Tropical Diseases (TDR), wlll contlnue development of potential macrofilaricidal drugs for both onchocerciasis and lymphaticfilariasis. One drug, CGP 6140 (Amocarzine), has already undergone numerous clinical trials in l{est Africa and Latin America agalnst onchocerciasis, while two other compounds, CGI 18041 and Ul,lF 078, are in the preclinical development phase, prior to possible use in man. 1.9. At the threshold of the fourth financial phase,special attention will continue to b€ paid to rigorous management and to the greatest possible savings compatible with the pursuit and achievement of the Programs obJectives. The management seminars, which were started in 1987, for theinitial area, and 1990, for the western extension, continue to bear fruit. They make it possible to acguire and exchange practical notions of management, review existing procedures in the various fields of administration, and study proposals and innovations aimed at improving cost- effectlveness. The computer support, which was introduced firstly in thefield of budget and finance, ls being extended progressively to the other fieldsof activity ofadministration: personnel, supplies, equipment. In each fie'ld, steps are taken to put in place programns compatlble with those in the l{HO headquarters. 0cP/91 . I Page 5 2. OVERVIET OF THE PLAN OF ACTI()II 2.1. The Plan of Action and Budget now includes a new unlt, the Devolution Unit, reflecting the concern of OCP to group together and strengthen all the activities in this field. One of the pillars of devolution will continue to be formal, 'in-service or on-the-spot training, partlcu]arly in the fields of epidemiology, health services management, statistics and data processing. Nationals will thus be trained to take over devolution activities at all the stages (planning, supervision, execution and evaluation). Furthermore, the unit will promote activities related to the lnformation and mobilizatlon of al'l the parties involved, and see to lt that the necessary technical assistance is provided to the Participating Countries. Socioeconomic development actlvities come withln the framerork of devolutlon and are henceforth attached to the unit. 2.2. In the in'ltial area, larvicide treatments will, as ln the past, be concentrated on certain zones ln the east and south-west subjected to reinvasion before the extensions were made. In the southern extension, it ls necessary to continue the vector control operations with the same intenslty. In the western sxtension, the operations wiII continue to cover the greaterpart of Guinea and almost the yhole of Sierra Leone. 2.3. Post-control studies, which will last two years, will be conducted ln the zones where larvlclding will have been deflnltively stopped. These studies are aimed at checking uhether blackf'lies vhich recolonlze the onchocerciasis-freed zones are really without any infection or at least that their infection rate is negliglble and does not aIlow recrudescence of the di sease. 2.4 Intenslve lvermectin distributlon has become an important characteristic of the Prograrme and will be continued ln the zones at high risk of onchocercal blindness as vell as in the northern part of the western extension which is not under larviciding and where the use of vider crlteria for the selection of villages will make possible an increase of the treatment coverage. The national teams wlll be relied on for the carrying out of these activlties, with the help of several non-governmental organizatlons (NGOs) and the supervision of OCP staff. Efforts will also be made wlth a vlew to passive dlstribution combined vith training, almed at lmproving the qua'lification of the responslble offlcers, and the raislng of the awareness of the comnunitles. 2.5. Entomological and epldemiologlcal evaluatlon will be contlnued in the zones under larviclding as well as post-control surveillance activltles. The Biostatistics and Information Systems Unit wlll continue to play a key rolein these fields by undertaklng data entry and processing. Eptdemiologlcal modelllng yill continue to be used to the fullest extent posslble ln the interpretatlon of results obtained and will constltute an increaslngly refined tool adapted to the complexity of the situatlons to be analysed. Just as so far, one of the Unit's dutles will be the supervislon, development and maintenance of the OCP computer equlpment. /s0cP Page rl 6 I 2.6. OCP will continue to pay particular attention to studies and research, which is necessary for the progression of its actlvltles and the malntenance of its efficacy. The main fields witl remain vector control, epidemiology, hydro'logy and hydrobiology. Studies and research wlll, more and more, be undertaken by OCP staff with secondary external support. The Onchocerciasls Chemotherapy Project (OCT) will continue with its research with a vlew to the development of an effect'ive macrofilarlclde. 2.7. For the execution of the Prograrme, rigorous management, cost-savin9, optlmum rational use of management prlnciples. the watchword wtll still be use of conputer resources and 0cP/9t . I Page 7 3. PLAN FOR IVERHECTIN TREATHEI{T 3.1. The experience acquired from monitoring the annual d'istribution of ivermectin and the resujts obtained from the yearly ophthalmological eva'luation of the effects of iarge scale ivermectin application on morb'idity' have reaffirmed the beneficial effects of ivermectin on the eye and the encourag.ing safety record. The proven beneflt has resulted'in easy acceptability which has enab'led the treatment coverage to be consistent, around the optimum of 60I for the protection against the risk of onchocercal eye lesions and blindness. g.2. It has been shown that large-scale ivermectin treatment given on a yearly basis does not interrupt the transmission of the parasite. A study lo determine the effect of mu'lti-annual ivermectin treatment on transmissionis therefore being conducted. 3.3. Large-scale ivermectin distribution will be undertaken in all the mapped areas of the oCP with a high risk of onchocercal blindness. This aclivitywi'll be carried out by nationals of the Participating Countries with superviiion frorn OCP personnel. Certain river basins vill continue to have i vermecti n di stri buti on through non-governmental organi zati ons (NGOs) . g.4. Wider criteria for the selection of villages to be treated vill be used, particularly in the northern part of the western extension area. This will increase the extent of ivermectin distributlon. In all the areas' a drive to intensify the distribution is envisaged. In this respect researchinto neh, or alternatlve yays of distributing ivermectin and lmproving treatment coverage will be addressed. 3.S. The passive dtstrlbution of ivermectln, vhich is done through established heajth institutions in the various countries, will receive special attention. In addttion to training, aimed at lmproving or equipping the staff at these centres with skills for the proper documentation of the ivermectin glven, all effort nill be made to €ncourage more use of ivermectin through passive distribution. Health education to emphaslze the need for annual and long-term treatment with ivermectin for lts beneficial effect, will be provided through the fixed health centres. OCP will ensure the regu'lar supply of ivermectin to these instltutions. 0cP/9r . r Page 8 4. GEI|ERAL COITSIDERATTONS ON THE PROPOSED BTDGET FOR 1992 tst32,453,000 4.1. The P'lan of Action and Budget for 1992 is presented, according to the pattern of previous years, by "programle activity" (sections 5.1 to 5.11). To be noted, however, are two changes aimed, on the one hand, at highlighting the importance of devolution and, on the other hand, at grouping together the activities of the Office of the Prograrme Director and administration and management. To this end: to the usual Programne activities, most of which correspond to the main subdivisions of the OCP organizatlon chart (Annex I), have been added, starting in 1992, the activlties of "Devolution"; these activities whlch, hltherto, have been included in the budget of the Office of the Prograrme Director, will henceforth appeEr as a separate Progranme activity, placed under a unit newly created for that purpose; the Office of the Programne Dlrector, wlthout the activlties of "Devo'lution", will be presented jointly vith the "Administration and Support Services Unit", as well as "Admlnistrative Support in Geneva"; thus, all the costs considered as administrative costs wi I I be grouped together. 4.2. Table I gives a synthesis of the costs by Prograrme activity. It contains a surmary of the Third Flnancial Phase (1986-1991), and the amounts proposed for 1992. Figure I presents graphically the proposed budget for 1992 by Programe activity. 4.3. Each Prograrme activity comprises a series of categorles of expenditure. Table 2 gives a synthesis of the costs per category of expenditure just as for the Programne activities (sunmary of Thtrd Financial Phase and proposa'l for 1992). Figure 2 presents graphically by category of expenditure the proposed budget for 1992. 4.4. Table 3 combines Tables 1 and 2 for 1992: surrmEry by Programe activity and category of expenditure. @neral ronrks 4.5. In preparing the budget, each activity is reviewed as well as each personnel post so as to maintain only rhat is essential to the execution of the Prograrme, in an endeavour to achieve maximum cost-effectlveness. 4.6. The proposed budget for 1992 amounts to tS $32,453,000 The average costs used for the calculation of the budget are shown in Annex II. Presumed annual inflation rates, as well as personnel and consultant statutory requirements, have led to the following percentages of lncrease compared to 1991: - Professional staff members - General service staff members - Consultants - Supplies, foreign procurement - Supplies, local procurement - Services 7.52 11r 4t 8T 10r 8T 0cP/91 . I Page 9 4.7. The approved budget for 1991 is US $34,355,000. From 1991 to 1992, there 'is therefore a decrease of US $1,902,000' i.e. , 5,5r. The sav'ings expected despite the increased costs, are due mainly to a decrease of the budget of certain categories of expenditure (operational travel, contracts, aerial operations, operating costs, larvicides), as will be explained hereafter. Annex III shows the evolution of the rates of exchange of the US doilar, in percentage, from 1982 to 1991. CATEGORIES OF EXPET{DITURE 4.8. The categories of expenditure are the components of the Programne activities. A study by category therefore gives an account of the various factors which, in addition to the rate of the US dollar assumed in the preparation of the budget, have an effect on the budget leve'|. The order followed in the review hereunder is that of Table 2. Personnel servlces 4.9. To have an overall view of the personnel working for the Onchocerciasis Contro'l Programe in I{est Africa, its two components have to be recalled: in the initial Progralrme area and the southern extension(Benin, Burkina Faso, C6te d'Ivoire, Ghana, l.lali, Niger, togo), OCP has its own personnel working under HHO contracts; in the western extension (Guinea, Guinea Bissau, western l,lal i , Senegal , Sierra Leone), the governments of the Participating Countries put at the disposal of the Programne national teams whose personnel remains employed by the respective governments. The permanent personnel working for the Prograrme ls therefore planned to be as follows in 1992: OCP personnel l{estern extension personnel 514 263 Total 777 In addition, 81 part-time rorkers will be employed for epidemiological activities. OCP Personnel 4.10. The OCP personnel will decrease as the Prograrme progresses and the devolution process ls implemented. Furthermore, wlth the putting in place of the Fourth Financial Phase, plans are being prepared with a view to harmonizing employment conditions in the whole Progranme area' i.e., by progressively generalizing the conditions applied so far ln the western extension. Horever, as long as OCP continues to exist, some OCP staff members in both the professional and general service categories will b€ needed for the functioning of the headquarters in Ouagadougou and some operational and research centres (Bamako: l,lali; Odienne, Bouake: COte d'Ivoire; Kara: Togo). 0cP/91 . r Page l0 4.11. The following table presents the total number of OCP posts approved in previous years and what is proposed for 1992: Unit Total number of posts 1 987 1 988 1 989 1 990 1 991 1 992 Proposed VCU 544 493 447 412 412 379 EPI 40 37 27 28 27 25 BIS 4 4 I 4 3 DEV 5 EC0 3 3 1 1.5 1.5 ocT 2 2 2 2 2 2 DIR/ADH 200 120 110 108 106. 5 100 TOTAL 789 659 591 555. 5 553 514 The following table presents a breakdown of the above by Professional and General Service posts: mit Profassionrl s 0enrrrl scrvico r0t? t9t8 rete r 990 lltI r092 P roDosrd IEEI r 9Et ilt9 le90 te9t re92 Proposcd YCl, 3l 30 2E 22 22 IE 50r {63 t I 390 3e0 36r IPI 5 5 { 5 I 2 35 32 23 23 23 23 us 3 2 2 2 I I 2 2 2 2 0Ev 1 I tc0 2 I I I I I 2 0.5 0.5 0cr I I I I I I I I I I I 0tR/roll 22 t2 ll t2 r2 I IE t0t 99 96 9{.5 9t I01il, 6I 52 {l t3 t2 35 122 601 5lt 5 r2.5 5il fi9 I 0cP/9r . I Page Il The decrease in 1992 compared to 1991 is therefore 39 posts (7.12), i.e., 7 professionals and 32 general service staff members (16.78 and 6.3t respectively). The differences are explained under the respective Programp activities. As a resu'lt of these reductions, and in spite of cost increases, the cost of personnel services wil'l decrease by US $395,000 as compared to lgg1. To reduce the cost of personne'l services in future, in terms of amount and percentage in relation to the whole of the OCP expenditures, personnel reductions wi'll have to be continued and the harmonization of employment conditions implemented. Details on this latter point, which had not yet been finalized at the time of preparation of the 1992 budget, will be provided during the twelfth session of the JPC. 4.12. The number and distribution 'in percentage of OCP personnel by sex and country of origin as at 31 l,lay 1991 are given in Annex IV. Annex V shows the trend of the cost of personnel serv'ices from 1982 to 1992, excluding consultancy services. National tean personnel 4.13. The personnel of the natlonal teams, are put at the disposal of the Programre and the sa'laries and allovances are paid by their governments. oCP's part is limited to individual lump sums paid according to each person's function and to subsistence allowances for travel on mission outside the duty stations. The fo]lowing table gives the total number of persons made avai'lable fu]l-timE to the Prograrme for the entomological and hydrological activities: Activity Year 1986 1 987 I 988 I 989 1 990 1 991 I 992 Proposed vcu Entomology llydrology 103 1 146 4 311 8 335 16 322 16 239 16 224 16 TOTAL 107 150 319 351 338 255 240 As regards epldemiological activities in 1992, 23 staff will be employed full-time, and 81 part-time. 4.14. The details by country are given under the VCU and EPI sections of the budget. The increase in the number of EPI posts and the concomitant decrease in VCU posts are due to the extension and intensification of ivermectin distlibution programtes in western ilaIi, Senegal and Guinea Bissau, without larviciding operations. The OCP budget for the functioning of the national teams is shown under the corresponding category of expenditure. 0cP Page le l.l 12 Consultancv services 4.15. These services include, firstly, consultants used by OCP particularly for activit'ies related to ivermectin distribution and experts who contribute to research work in the fields of insecticides, entomology, hydrology, hydrobiology and cytotaxonomy. Included also are short-term professionals (10 planned for 1992) and a United Natibns Volunteer in the field of epidem'io'logy. The proposed budget is equal to that of 1991. Ooerational travel 4.16. Strict measures continue to be taken as regards Operational travel. There is an expected decrease of US $208,000 compared to 1991. Contracts 4.17. This category covers research and service contracts signed with companies, universities and other institutions in support of specific OCP activities, for example, aquatic monitoring, Argos teletransmlssion, maintenance of hydrological stations, and contracts signed as part of the Onchocerciasis Chemotherapy Project. The budget for this category of expenditures is equal to that of 1991. Aerial ooerations 4.18. Aeria'l operations continues to be an essential component of the Prograrme's activities. This category comprises the aerial contract(helicopters, Turbo Thrushes, liaison aircraft) and fuel. According to the aeria'l contract signed for the period 1990-1992, there is no change in the cost of fliSht hours (exc'luding fuel) from 1991 to 1992. The estimated flight hours amount to 7,800 compared to 8,350 for 1991, which leads to a decreaso, under this category, of US $315,000 compared to 1991. A diagram showing the trend in the costs of aeria'l operations frm 1982 to 1992 is given in Annex VI. Ooerating costs 4.19. These are costs related to the logistic needs of the Prograrme (e.9.,fuel, spare parts) and to the administrative infrastructure (electricity, water, telephone, watchmen). Everything possible will be done to maintain the operating costs within the lowest possible limits which will not ieopardize the smooth running of the operations. Despite the increase in the prices of fuel and services, the required amount remains the same compared to 1991. Larvicides 4.20. For the first three years of the Fourth Financlal Phase (1992-1994), insecticide requirements will be more or less the same as those of 1990 and 1991. Spraying operations will stil'l cover some zones in the inltial Progranme area. In the yhole of the southern extenslon larvlciding will be selective and seasonal. In two western extension countries, Sierra Leone and Gulnea, larviciding has to be continued with a sufficiEnt intensity and duration on the permanent rivers, which have a high rainy-season discharge, correspondingto hyperendemic foci. The larviclde reserveswhlch fell greatly at the end of 1990, have increased to a satlsfactory level because of the relatively high amount approved for 1991 (US $6,120,000). The amount requiredfor 1992, US $4,250,000, is consistent with those of previous years. 0cP/91 . I Page 13 Suool ies 4.21. This concerns the procurement of recurrent items as opposed to capital costs. The estimated amount is US $10,000 less than that of 1991. Statutorv [Betings 4.22. The budget remains the same compared to 1991. FeI lovshios and traininE 4.23. This category will continue to cover current fellowships, netr ones, and field training, which are fundamental activities particularly vith a view to devolution. The amount is equal to that of 1991. National teams 4.24. As explained above under the "Personnel services" category, the governments of the western extension countries put at the disposal of the Prograrme national teams whose salaries and allowances they pay. In addition to lump sums, OCP pays them per diem when they travel on mission. The teams work under the technical supervision of OCP which a'lso provides the vehicles and fuel and other required equipment. The amount required in 1992 is equal to that of 1991. Other catesories 4.25. Administrative support in Geneva and capital costs wi'll be dealt with under Programme activlties. Budqet swmarv 4.26. The proposed budget requirements are surmarized in the following tables and figures: Table Fi gure Table Fi gure Table 1-1-2-2-3- Budget by Prograrme Activity Budget by Prograrme Actlvity Budget by Category of Expenditure Budget by Category of Expenditure Budget surmary by Programe Activity and Category of Expenditure Further details are given in Tables 4 to 16 for each Prograrme activity. 0cP/91.r Page 14 IABLE I BIJDGEI BY PROSRAIIi|E ACTIYITY (us t) tt Progrrnm Activity Yrctor Gontrol Epidcriologicrl Evalurtion Biortrtistics I Info. Systcrs Sociocconoric Dcvcloprcnt ( | ) DCvol uti on Chrrothcrrpy Projcct 0fficc of thr 0ircctor Adrinistrrtion I Support tcrvicts Adrinirtntivc Support costs 0cncvr Strtutory llectings Crpittl Co6ts (2) Applird Rmcrrch rnd Environmntrl Ioni tori ng IOTAL P l{ A S E III t- -lr 990 I 3 , 925,385 ilt,395,3C5 30,t32,300 13t,355,000 turc 989 Expcnd I 98C/ urttErprndi Proposcd r 992 00, t{7 I I ,2t2 l.21,555,7C2 I I ,c52 i 1,159,558 I I ,818 I 253,8I0 I I ,lt8 | l2l,c3t I I I I I I ,{13 I l,c3t,93t I I ,ccz I t,t5{,658 I I ,7t3 I 2,532,C98 I I ,oi2 I 322,Ct1 I I ,2t0 | 309,8$ I I I I ,086 ,857 000 000 000 5 3 I 22 000 000 000 000 3C 80 28 3r0 305 907 2l 58 095 5r2 390 95{ c33 577 02r t07 { { 9 9C{ ,000 ,000 2,l9C,tl(}(} I 52 000r5332, (t) As fron 1992, Socioeconoric dcvelopaent rill be includrd in'l)evolution' Progrrrre Activity (2) Crpitll cost cxpenditures for t986 to 1989 rre includcd in thc expcnditures of thc Prograrm rctivitics rbove. Iotc Ivcrrrctin: 900,000 tablcts vllucd rt USI 3 I trblet, provided frlc of chrrgc by Icrck Shrrp rnd 0ohre. ll ll I lpprovcd I ll lli tesl itlt-ttltl i2t,909,000 | tlll i t,751,500 | IttlI 327,500 illtlI t{2,000 |lllltllltltl I I,Cil,500 | ll ll I t,2t0,500 | ll ll| 2,C85,500 |lltl| 3t0,000 illtl| 305,ooo i ll llI 919,500 illtltllllltllltltltltl -l -l 0cP/9r . r FIGURE 1 Pase Is 1992 BUDGET BY PROGRAMME ACTIVITY 8910 6 5 4 1 Vector control 2 Epldemlologlcalevaluatlon 3 Blostatlstlcs & lnformatlon Systems 4 Devolutlon 5 Ghemotherapy Profect 6 Offlce of the Dlrector 7 Admlnlstratlon & support servlces 8 Admlnlstratlve support costs Geneva 9 Statutory meetlngs 1O Capltal costs Total 7 3 2 1 (us $) (Y") 68.91 5.56 o.89 2.97 6.77 2.24 7.88 1.O5 o.94 2.79 22.365.OOO 1.803.OOO 288.OOO 964.OOO 2.196.0OO 727.OOO 2.558.OOO 340.OOO 305.OOO 907.OOO 32.453.OOO 100.oo 0cP/91 . I Page 15 IAELE 2 BUDGET BY CATEGORY OF ETPEIIDITURE (l,s t) Category of cxpcnditure RECURRE}IT COSTS Pcrsonnrl rcrviccs Conrul trnto Oprrrtionrl tnvrl Contrrcts(rcscrrch I othrrs) tcrirl opcrrtions 0pcrrting costr Lrrv ic irlcs Suppl ios Iceti ngs Fcllorships rnd trrining xrtionrl tcrrs Adrinirtrrtivc support costs - Gcnevr Sub-totrl CAPIITL COSN Offico furniturc llrtr proccsting cquipmnt Ychiclrs Icchnicrl cquiprcnt Bui ldings Sub-totrl l-l- ture 989 Expend I980 I22 '00 { 36,081,{37 2,991,8{8 10,t38,5c3 t8,725,091 8 , zCC ,00{ 0 t09,967,377 58,8il 5r8 933 036 0c2 r03,10822 2,269,220 5982 I,719,839 09 98 c8 3 0 21 I93 ,717 855 550 I , t27 ,988 TOIAL 3t , 355 ,000 32 ,153 ,000 P H A S E III 9C1 05 r952 urttrpcnd 702,855 9 0 ,117 , {71 r 990 886 8C{ ,8 6,33t,999 2,t99,127 {,355,310 50t, 2t0 309, 8t5 306 , {07 6{ 1 ,086,057 6 0793r 322 I 3503{29 587 215 58 58 c{ 52 221, t5 I I I t1,395,3C5 | 30,t32,3C0 I -l I 991 I,202,000 I,375,000 I ,000 ,000 3{0,000 -t- 33,t05,500 25 , ooo 5{,500 c50 , ooo 10,000 -t- 0 5 0 2 I , 533 ,000 555,000 rovcdApp -t 50033{ 000 5009{9 0 0 0 00 00 00 5 0 20 000 000 0 30 3 02 Propored r 992 10,939,000 I,217,000 I,167,000 2 , {89 ,000 c ,500 ,000 2,512,000 I, 250 ,000 5{5,000 305,000 317,000 965 ,000 3{0,000 000il03 7i ,000 0 25 ,000 907 ,000 000 000 000 597 198 I I ll ll I I ll ll t- 3 2t 5 -l -l -l FIGURE 2 0cP/91 . I Page 17 1992 BUDGET BY CATEGORY OF EXPENDITURE 121 314 17 516 (us $) 1 Personnelservlces 1O,939,OOO 2 Consultants 1,217,OOO 3 Operatlonal travel 1,1 67,000 4 Contracts (research & others) 2,489,OOO 5 Aerlaloperatlons 6,500,000 6 Operatlng costs 2,512,OOO 7 Larvlctdes 4,25o,oo08 Supplles 545,OOO 9 Meetlngs 3O5'OOO 1O Fellowshlpe and tralnlng 317,OOO 11 Natlonalteams 965,000 12 Admlnlstratlve Support costs - Geneva 34O,OOO 13 Offlce furnlture 25,OOO 14 Data processlng equlpment 77,OOO 15 Vehlcles 597,OOO 16 Technlcal equlpment 198,OOO 17 Bultdlngs l O,OOO 6 (v") 33.70 3.75 3.60 7.67 20.o2 7.74 13.10 1.68 o.94 o.98 2.97 1.O5 o.o8 o.24 1.44 0.61 o.o3 Total 32,453,OOO 100.oo 0cP/91 . I Page I8 IrSrE 3 SUOOET FOR 1992. SUTTTRY IY PROGRATTI IilIYNY ilO CIIEGORY OF EIPIXOIII,f,I (us t) lctltl Cltrgory of uDrndltun RtcljnnEtI cosrs Pcrsonnrl senices Conrultrnts 0Frrtionrl trrvrl Contrrcts (rrsurch I oth!rc) lcrirl oprrrtions 0pcrrtlng costs lnscct i cldrs Suppl ies Fellorshigs rnd trrinlng lrtionrl lrus lfi lnirtrrtlur SuD9ort costs-0urvr Strtuto?y rcctlngs Sub-totrl l-l-l- cmlTrt cosTs 0ffio furnltun 0ltr procosling rquipnnt Irh I clcs Icchnlcrl rqulDnnt Sub-totrl hlldings Progrum ructor0t 52{,000 000 000 9t' 000 25, 000 l2t ,000 000 000I 1,000 I I I35,000 123,ofl I Ycctor Contm 000 000 000 122 n2 I00 20c ,000 6 ,500,000 -t-l-l- t0,000 2{,000 ct2, 000 ,000 000,000 ,000t,250 t00,000 00050 22, tC5, ooo {6?,000 000 000 -l-t-l-l-l- ,000Irc tpidulo- log I crl [vrlurt. 592 ,000 t ,103,000 2tt,000 t0,000 t2,000 30,000 5,000 000 ,000 3I 230,000 1t0,000 t00,000 000 000 000 000 000l5 t50,000 2 22 5 I 2t,000 -l-l- I,ill,000 9t,000 urt -l-t-t-l-t-t-l-l l-l I Chuo- tharrpy ProJrct I I Itdrintr Itrutiott I I I ttttltl8tostttir-l i Itics t Inflhvolutionl I Slstors i ittl 000 5l,000 t9c I I I I I I t5g,00o i I I It6,000 i t I t5,000 | I I t0,000 l2,t0c I I I I I I I,000 i I I I I I I I I I I il?,000 i I I I I I I I I I I I I I 000 000 000 000 20 32 350 05 000 3t0,000 -t -t -l , lg!,00090000gc{ I I i2 I I I ie I ,000 ,000 000 55, 000 II 20 000 000 t9 ,e0l -t-t-l- 00 I I l2 I I I e6{,000 12,t96,000 I Strtuto ry ll9sI$t t05 ,000 305,000 0 305,000 Iotrl r992 10,939,0oo il tt l, tcl,000 -t l-t I r-l 000ll ,000t2 0005{6 000 l-t oe ,000 500,000 {,2i0,000 5{5,000 2, c, 2, 000 000 000 000 3fl 065 3r0 305 ttI I i3 25,000 59? ,000 t 91,000 0,000il tt tol ,000 -l l-l 12,$t,000 I ,000 ,000 3t2,000 | ,000 I, -t 0cP/9r . r Page 19 5. ESTIHATED COST BY PROGRTfl{E ACTIVITY(Note: see paragraph 4.1. above) 5.1. Vector Control Unit (VCU) ts $22,365,000 Introduction 5.1.1. Fol'lowing the discussions which took place durlng the eleventh session of the Expert Advisory Cormittee (EAC) held in Ouagadougou in June 1990 and the decisions taken by the Joint Programe Cormittee at its eleventh session (Conakry, December 1990), the plan of action of the OCP Vector Control Unit takes into account the lnitlal Progranme area, the southern extension and the southern part of the restern extension (Guinea and Slerra Leone). Zones to be treated(See map in Annex VII) Eastern zone includlng the south€rn extenslon 5.1.2. In the initial Programre areawhere larviciding operations have been going on for some fifteen years now, only the zones having been subiected to reinvaslon before the start of the extensions will be malntalned under larviciding. This mainly concerns: the Black Volta and its tributaries downstream from the confluence with the Kulda; the Keran and its tributaries upstream from the confluence wlth the Koumongou; the Kara and its tributaries upstream from the confluence with the Niankpe; the Mo and aIl its tributaries; the upstream section of the tributaries of River Nlger in Benin; finally, the Kulpawn-sissili basin in Ghana and the l{hite Volta downstream from the confluence vith the Nasia. In the southern part of C0te d'Ivoire, whlch has been under treatment for only some ten years now, larvlcide spraylngs vlll be made on: the lower Bandama downstream of Lake Kossou; the N'zi downstream frm the confluence with the Sepie (north of Fetekro); the Comoe downstream from the confluence with the Kinkine up to the Abengourou bridge and if necessary up to Betie (ln case of presence of savanna species). a 0cP/9r . r Page 20 In the southern extension area (Ghana, Togo, Benin) west of the Volta Lake, only River Pru will be treated. To the east of the Volta Lake, all the rivers har6ouring breeding sites of the S. damnosum conplex will be treated wlth the exception of the smal'l montane rivers at the border between Ghana and Togo colon.lzed mainly by S. squamosum and S. vahense, vectors of non-blinding onchocerciasis. However, seasonal treatment could also be made if savanna species are ident'ified in this zone. l{estern zone including the extension 5. 1.3. In the initial area, larv'iciding wi I I be suspended on the }Jhite Bandama upstream from Niaka and the Ban'ifing IV. After two years of post- control in 1990 and 1991, treatment will also be suspended definitively on the Dogon plateau and on the Koni. The l,larahoue, the Sassandra, the Bagoe, the Baoule, the Niger at Bamako and the Fie yill be treated regularly. Just as for the eastern zone, they are watercourses forming part of the southern extension in COte d'Ivolre(Iarviciding took off in 1979-1980) or watercourses reinvaded before the start of the western extension. In Guinea, larviciding wiII be continued in the zones where the savanna species and S. soubrense l'lenankaya form develop and transmit the dlsease evenif onty seasonally. Zones excluslvely containing S. squamosum and S. vahense will not be treated; this mainly concerns the Baoule, tributary of the l,lilo, the Niger upstream from Laya-Doula and the Makona ln the border region of Gueckedou. As regards Sierra Leone, it is planned to carry out larviciding in the whole country. However, the uncertainties concernlng the gravlty of the dlsease ln the northern and north-western parts of the country remain. The attempt to temporarily eradicate S. soubrense B which could not take place in 1991 has been postponed to 1992. The additional requirements corresponding to this operation have been taken into account. Larvicldes S.i.4. B.t. H-14 will be used mainly at discharges less than t5 m3,/sec. phoxlm. ovraclofos and Abate (temephos) will be used principally between 15 anO ZO h!lse"., phoxim and pyraclofos preferably as the water levels rise and Abate during the flood-subsidence perlod. permethrin and to a lesser degree carbosulfan (considering its price) vill be employed in practically all the baslns at hlgh vater ln rotation with lU"t", piraclofos or phoxim in order to respect the number of maxlmum cycles Oeieririhld by the Ecological Group (a maxlmum of six consecutlve cycles for permethrln and ten for carbosulfan). The requirements for 1992 are as follows: I itres I ltres I itres I itres I itres I itres Abate B.t. H-14 Carbosulfan Permethrin Phoxim Pyraclofos 72,800 253,800 21,000 21,000 48,000 2 1 ,000 a 0cP/9I . I Page 2l Entilploqical evaluation netrork A general picture of the entomological evaluation network is given ln Annex VIII. 5.1.5. l{ith regard to the western extension, several changes are to be noted. Fot'lowing a reassessment of the needs on the basis of the evolutlon of the activities, two operational bases have been closed in Guinea (Labe, Gaoual). fotlowing the decision not to carry out larvic'iding ln the northern part of the western extension, an operational base has been closed ln Senegal(Kedougou) and four in l,lali (Bamafele, Faraba, Kayes, Toukoto). In addltion, in Mati, four bases have stopped their entomological evaluation actlvities and have been converted into passive ivermectin distribution centres (Bamako, Bafoulabe, Kenieba, Kita). 5.1.6. Changes have also taken place, or are planned, in the lnitial Progranme area. In t{ali, the closure of a subsector (Sikasso) is planned for the end of 1991. In Niger, the Nlamey subsector will also be closed at the end of 1991. Its activities will be taken over by the government of Ntger as part of devolution. In Burkina Faso, the Bobo-Dioulasso sector, wlth sme 30 workers, has been turned into a subsector because of the reduced actlvltles in the initial area. It now has 17 workers. Finally, the Ouadougou subsector now has only one catching team. These subsector closures and the reduced personnel (4 professlonals and 28 general service staff members less ln 1992) show that the budgetary rlgour remains an absolute rule. For the other offices, lt ts not posslble at the moment to undertake new personnel reductlons without jeopardlzlng the quallty of the rork done. It should be stressed that entomological evaluation results are an indispensable tool for the taking of operational declslonsparticularly as regards the resumption or temporary suspension of larviciding. Furthermore, while it has been possible to reduce the reinvaslon monitoring network significantly because of the excellent results obtained in 1989 and 1990, it has, on the other hand, been necessary to lncrease post- control or post-'larviciding studies which have proved to be indtspensable for a period of two years after the definitive cessation of larviciding. These studies are aimed at checklng whether the blackflies which recolonize the onchocerciasis-freed zones are really free fron any lnfestatlon or that at Ieast their rate of lnfestation is negligible and does not allow recrudescence of the disease. Aerial ooeratlons 5.1.7. The year 1992 will be the third and last yearof the current aerial contract. The results have been satisfactory particularly because of the new helicopter spraying systems. Besides, on both the helicopters and fixed-wing alrcraft, a system for automatic recording of sprayings made (number of points, time, quantity of insecticide used) allows a better monitoring of the work of the pilots. The Progranme will, on average, use elght hellcopters whose number will vary according to the seasons, whlle the tvo Turbo Thrushes wil'l be used only in the rainy season. The number of flight hours has been estimated al 2,750 for the eastern zone and 4,950 for the western zone; 300flight hours should be added forthe liaison aircraft. This glves atotal of 8,000 hours. 0cP/9I . r Page 22 Aoplied research S.1.8. As already mentioned in 1991, the necossary researches ln the extension zones have now been completed. New lnvestigatlons on the cytotaxonomy of the vectors, the identification of adult blackflies or Onchocerca strains and the optimization of aerial larviclding are now carried out UV VCU staff who have received adequate training in these differentfields to which should be added their experience and field knowledge. Consequently, research contracts have been reduced to a strlct mlnimum and are aimed mainly at helping VCU staff ln fields where the workload makes them necessary (insecticide research, dissections or sorting of hydrobiologlcal samples at certain times of the year). The budget proposed for research contracts for 1992 amounts to US $35'000. l{onltorinq of the aquatic envirorment 5.1.9. The monitoring of the aquatic environment vill contlnue to be carried out according to the reconrnendations of the Ecological Group vhose twelfth session yas held at the end of February 1991 at Bouake (C0te d'Ivoire). During that sesslon, it was confirmed that pyraclofos and phoxim would henceforth form part of the operatlonal lnsecticides. In the initia'l area and in the southern extension zone, the monitorlng of the fish fauna is undertaken by the national teams whlle that of the entmofaunais carried out by the VCU teams. In 1992, the latter wlll particlpate alsoin the screening of neu products or new insecticide formulations. The monitoring wiII be focussed mainly on the baslns treated vlth "hard" insecticides (permethrin, carbosulfan). In the extension zones, service contracts have been s'igned with the national teams and the study stations selected in Guinea and Sierra Leone are under monitorlng. Service contracts 5.1.10. Service contracts are mainly signed with organizations working in the field of hydrology (teletransmisslon, maintenance of the hydrologlcal network) or hydrobiology (data analysis, help to national teams)' The folloving service contracts are proposed for 1992: - Hydrobiological studies on new larvlcides - Aquatic monitoring by the national teams - Ha'intenance of the hydrological stations - Contract for utllization of Argos Satellite System - Verification and flnalization of hydrological forecastlng models 10,000 90, ooo 8,000 43,000 20,000 TOTAL 171,000 Personnel S.1.11. The personnel requirements for VCU, including the staff of applied research and of the environmental monltoring groups, will be as follows(comparison rlth 1991 indicated): 1991 1992 - Professional staff members 22 18 - General service staff msmbers 390 361 TOTAL 412 379 0cP/9I . I Page 23 The decrease is due to the closure of four entomologlcal evaluation subsectors, the reduction of a sector to subsector level, and the transfer of one professional post to the Progranme actlvlty of "Devolutlon and Trainlng". Consultancv services 5.1.12. Consu'ltancy services are related to research activities in the fol'lowing f ields: Number of months - Insectlcides - Hydrobiology - Entomology - Aerial operations - Cytotaxonomy TOTAL 15 professionals appear ln the budget underIn additlon, 4 short-term "ConsuItants". Natlonal oersonnel 5.1.13. The natlonal personnel requirements for 1992 vill b€ as follows: 1 5 2 5 2 Post National Coord Dep. National Coord Entomologist/l,led. Off . Ento. tech. /Nurse Hydrologist Asst. hydrologist Adm. asst. Secretary Radio operator l,techanlc/Asst. mechanic Driver Storekeeper,/Asst. Storekeeper Vector collector Boatman/ass. mechanlc Hatclman TOTAL Gulnea 1 I 4 26 2 4 3 2 10 5 33 3 48 1 12 Total 2 2 6 42 4 8 5 3 13 7 50 4 72 3 19 Slerra Leone I 1 2 16 2 4 2 1 3 2 17 I 24 2 __:_ 85155 240 Budset 5.1.14. Th€ budget requirements for 1992 amount to US $22,365,000 which represents a decrease of US $2,604,000 conpared to 1991. This is explained mainly by a decrease of the costs of larvicides (US $1,870,000) made possible by adeguate stock replenistments effected under the 1991 budget, aerial operations (US $3OO,OOO), personnel (US $291,000) and other categories(us t143,000). 0cP/91 . I Page 24 IABLE { YECIOR COIITROL I,IIII (us t) Catcgory of crpcnditurc RECURRE}IT COSTS PERSOIITIEL SERVICES Chief YcU (l) Scientists ( I ) Iechnicel 0fficcrs Adrinistrrti vc Assistants clcrks, Etlnogrlphtrs rnd othlr Gtnlrtl Scrvicc prrsonncl Terporrry strff Sub-totrl rdc0r r 990 5 9.5 e.s -t- I P{lr I I Pti SRP P5/ P3l 390 t- { 2 POSIES - - -l r 991 il l0 390 2{ 9 I 3Cr 379 37 9 Exprndi turt 1992 i r98C/r989 I -t- -l- {I 9r99 52r386 2 , 55t, 228 9,712,{25 2,t52tgl2 I,5ll,08t c,705,1 78 2 , {08 ,103 I ,291 ,702 57,30{, {1 0 -t-t-l-l-l- 70 653121 (t) Chicf VCU rnd onr Scicntiot undcr contrrct rith'lnstitut frrngris dc Rcchcrchc sciontifiqur pour lc D6vcloppcmnt cn CooD6rrtion' (ORSIOI) (2) Sierra Lconc (llaintcnlncc of hydrologicrl nrtrork) P It A S E III Expc nd i turc c,759,{ll 362 ,053 529,3t3 c,33{,999 203,239 I98,3t3 I,9lC,t7l l, 355 , 310 2tc ,590 -l- I I ll I 35796{ 2 ftz555 Approvod I 99r -l- I 28 ,000 I,170,000 775,000 5 ,2C5 ,000 1 55 ,000 7 , {93 ,000 {05,000 30 ,000 850 ,000 6 ,800 ,000 23t,000 790 ,000 2 ,000 ,000 c,120,000 250 ,000 -l 0007CII 2t,9C9 ,000 Proposed I 992 00099I 1 10 ,000 cc8 ,000 5,115,000 1 00,000 l- 7 ,322 ,000 {72 ,000 700 ,000 c , 500 ,000 206 ,000 !15,000 2 ,000 ,000 1,250 ,000 300 ,000 5 ,0t3 ,000 -l -l 00036522, tt t- tltli teeo itl tlttilzi1r2i tt -t-l tllltl tllllltltttt tltltttllttllltt tllltltltltl tllltltltltltltltltltltl tlll -t-l- lltl -l-l-l tltlI Consultrnts itltli Unitrd llrtions Yoluntecr (2) itltl| 0pcntionrl trrvel Itllli Acrirl opcntionr itltlI Contrrcts(rrsclrch t othtrs) itltlI tlrtionrl tous itltl| 0pcnting costs itltlI Insecticides itltlI Suppl ics I tltltltli Sub-total Itl1lll tlI ToTAL Itl 0cP/91 . r Page 25 5.2. Eoideniologlcal Evaluation Unit (EPI) ts $1,803,000 Overvier 5.2.1. The activities of the EPI unlt for 1992 will be based primarily on the continuation of the intenslve distrlbution of lvermectln in high-risk areas of onchocercal blindness, the evaluation of areas where interruption of larviciding is planned, the selection of villages for surveillance of recrudescence, and the pursuance of the study to assess the importance of migration in the onchocerciasis-freed areas. There vill also be an extension of the areas covered by ivermectin treatment, as well as ophthalmological evaluation of ocular disease ln comnunities wlth low intensities of infection. Evaluation of the impact of ivermectin treatment as well as vector control wlll also be carried out. Distribution of lvermectin 5.2.2. The mapping of the southern extension area havlng been completed, the entire OCP area has now been epidemiologically mapped to facllltate the selection of the higtrrisk areas for large-scale ivermectln treatment. Large-scale ivermectin distribution wlll continue ln the previously mapped areas as well as in the identified villages of newly-mapped areas. It is envisaged that over 400,000 people will be covered through actlve treatmentyith ivermectin. Several NGOs will take part in the treatment, and they will carry out their activities ln speciflc areas within the OCP area. In all the other river basins the treatment wilt be carried out by natlonal teams with the required support and supervlsion fron OCP personnel as before. Adverse reactions to ivermectin have been very minlmal. However, monitorlng and documentation of severe adverse reactions to ivermectln treatment wlll be continued. The careful documentation of the effect of lvermectin treatment on the eye and the skinload of microfllaria ylll be contlnued, to underline the beneficial effect of the drug after repeated treatment. 5.2.3. In the northern part of the western extenslon area, where no Iarviciding is being carried out, there will be a continuation of the extension of the coverage of lvermectln treatment uslng a wlder criteria for the selection of vlllages. The aim is to place over 65,000 people under ivermectln treatment during the year. The river baslns north of the Tlnkisso river will constltute the zones to be involved. The teams to perform the distrlbution will be made wholly of nationals from the vartous countrles, in collaboration with OCP EPI personnel who will play a mlnlmum supervisory role. It is anticlpated that more N@s will become lnvolved in lvermectin distributlon in the year. The possibillty of other ways of ivermectln distrlbution, for example tagged onto other national health dellvery systems wiII be addressed. The study on the effect of biannual ivermectin treatment on transmission will continue in the Hako Area. In the Rio Corubal basln in Guinea Bissau ivermectin treatment will be given three tlmes ln the year. 5.2.4. rlith increasing use of lvermectin through passive dlstributlon, proper documentation and control will need to be instituted. Selected staff at the health centres and other health institutions responslble for passlve distributlon yill be given a short training aimed at improvlng or equipping them wlth skills for proper documentation and record keeplng of the treatment. Efforts wlll be made to lncrease the use of ivermectin through passive dlstribution. Staff at the fixed health lnstitutlons wlll be encouraged to provide health education on the need for annual and long-term treatment wlth ivermectin. 0cP/9r . I Page 26 Interruotion of larvicidinq 5.2.5. Epidemio1ogical information will be collected from the river basins in the original OCP where it is planned to interrupt larviciding. Like in the past, data will not only be collected from the follow-up villages, but also from new first-line vi'l'lages selected in conJunction with the Vector Control Unit (VCU) and the Biostatistics and Information Systems Untt (BIS). The results from these se'lected areas will be discussed with VCU before a final decision as regards stopping of larvidicing is taken. The staff to undertake this epidemiological evaluation wlll be natlonals, under OCP supervision. The collection of migration history from those examined will continue, in view of the possible role of migrants in the reintroductlon of infection'into the onchocerciasis-freed zones. Epidemiolosical Survei I Iance 5.2.6. With more and more areas being removed from larviciding, net{ v'illages need to be se'lected for post-control survelllance. The selection of these villages wil'l follow basically what was planned for the previous year. At least three first-llne vlllages from each focus wlll be selected, each village belng examined once every three years and at least a village in the focus being examined each year. lligration Studies 5.2.7, There wi'll be a continuation of the migration studies to further clarify the lmportance of migrants ln the reintroductlon of infectlon lnto the onchocerciasis-freed areas. Further migratlon studies will be undertaken focussed on netr settlements and nomadic populations, for example, fishermen at high-risk locations. Eoidemiolosical Evaluatton 5.2.9. The traditional evaluation of vector control activities in areas under larviciding will continue. These areas will be certaln portlons of the southern parts of the original OCP area, the reinvaded areas, the problem spots and the extension areas. In an attempt to evaluate the effectiveness of vector control in interrupting transmisslon in the extension areas- where both larvtciding and lvermectin treatment are going on - it ls planned that evaluatlon based on the assessment of incldence of infectlon as revealed by skin snlps wlll be undertaken. OohthalrrcloEl cal eval uatlon S.Z.g. The ophthalmologica'l activlties will involve the evaluation of the effect of large-scale lvermectln treatment in the population. Follow-up villages ln Ghina, Guinea and tlali yill be examined to monitor the effect of ivermectin in controlling eye disease and preventing blindness. The assessment of the public health importance of ocular disease in comnunities with low intensity of lnfection wlII continue, extendlng to the evaluation of villages in genin and Togo. This is to help in determlning the threshold of endemicity level at which large-scale ivermectin wtll be instltuted. Conmunities in recently identified foci of the vector S. souamosum will be examined ophthalmologically to assess the publlc health importance of the prevalence of ocular onchocerciasis. 0cP/91 . r Page 27 DilA orobe 5.2.10 The testing of the DNA probe has demonstrated that savanna strains of the organism can be d'ifferentiated frm the forest strain. Further studies will however be needed to concentrate on the Sierra Leone strains usingmaterla'l already available, as well as fresh specimens to be collected from the area. Personnel 5.2.11. To carry out the activities outlined, the personnel requirements for the EPI unit will be as follows (comparison made wlth 1991): - Professionals - General service 1991 19924223 23 This shows a decrease of tuo professional posts. One post has been transfered to the new Devolution Unlt. The second follows an internal reappraisal and rearrangement of functlons geared torards lncreased use of natlonal personnel. 5.2.12 tn llne yith the task force requlrements for the management and coordination of lvermectin distributlon, an epidemiologist rlll be needed as short-term professional to coordinate the work, visit the potential fixed centres earmarked for passlve ivennectln dlstrlbution, and advlse on the best possible means of distribution as well as proper documentatlon of the use of ivermectln. Furthermore, he wlll evaluate alternative means of distrlbuting ivermectin and improving coverage. He will also advise on the incidence studies to be instltuted to evaluate vector control actlvities ln the areas where both ivermectin dlstribution and vector control are being carried out. Consultancv servlces 5.2.13. The following consultancy services are proposed: - |,ledical epidemlologlsts(including the short-term professional ) - Ophthalmologist Number of months 42 llational teams 5.2.14. National personnel is made avallable part-time by the western extension governnents for ivermectln distribution and epidemiological evaluation. The national teams also comprise full-time managerial and supporting staff: National Coordlnator, Deputy National Coordlnator, radio operator and others as the need may be. In previous budgets, full-tlme personnel had been included under the Vector Control Unit. As from 1992' ln tho three countries not under larvicidlng (Guinea Bissau, l,lali, Senegal), thls personnel will app€ar under the Epldemlological Evaluatlon Unlt. The situation will therefore be as follows in 1992: 5 J 0cP/91 . I Page 28 Part-tinp personnel l,ledical Officers Techn i ci ans/nurses Dri vers TOTAL Full-time personnel National Coordinator Dep. Nationa'l Coordinator Adm. Assistant Radio Operator Others (drivers, guards) Guinea l,lal i Bi ssau Senegal Sierra Tota'l Leone Guinea 3 14 8 25 1 7 3 2 6 6 1 6 3 3 12 6 10 45 26 10 21 14 Gui nea Blssau 81 l,lal i Senegal Total 11 1 1 1 I 3 I I 1 I 1 4 I7 3 3 3 3 1 1 1 1 1 4 TOTAL 23 In addition, the governments of six countries in the inttial area (Benin, Burkina Faso, COte d'Ivoire, Ghana, Nlger, Togo), will make avallable to the Programme one medical officer and 7 technicians/nurses for epidemiological activities. OCP vll'l pay them travel allowances. National medical oersonnel and health centres 5.2.15 For the intensification of ivermectln distrlbutlon, local doctors and nurses will be called upon to help in both actlve and passive treatment. Some fixed centres that will be mainly involved in passive distrlbution may be required to extend their services through moblle outreaches to the population at Iarge in the areas concerned. Travel and subsistence allowances and other logistics for this personnel may have to be covered by OCP. Budset 5.2.16. The budget requirements for 1992 amount to US $1,803,000, which represents an increase of US $48,500 compared to 1991. Savings on personnel are offset by increase on consu'ltants and National teams following intensification of ivermectin distribution. I 1 IIABLE 5 EPIOEllIOLOGICAL EVALUATIOTI (us tl 0cP/91 . r Page 29 Gategory of expenditure RECURRE}IT COSTS PERSOIIIIEL SERVICES Chicf EPI llcdi crl 0f f i ccr-0phthal rologi st Iedicrl 0ffimr Laborrtory,tcchnicel rsristrnte llurses ldri nistrrtive rssistrnt Clcrk stenogrrpher Clrrk rnd typist Iripor!ry stlff Sub-tot!l Consul trnts Unitcd tlrtionr voluntccr (t) 0pcrrtionrl trrvcl Acrirl oprrrtionr 0penting costr SuDpl ics Contncts (othrn) llrtionrl tcars Sub-totrl TOTIL Gr t- rdc P.5 P.5 P5/PI G.S G.S G.S G.S G.S r 990 r3 3 c 3 28 -t- -t- POSTES r99t 2 r3 6 3 2l 2l (l) 0uincr-Bissru (apidcriology) 28 -t-t- I,{59,558 I , 15{,500 I ,803 , 000 9 92 r3 6 3 25 25 Erpcndi ture I 986/ I 989 2,il3,052 386 ,550 {25,125 12,609 t 5{,708 e59, C22 35,000 llt,952 I,118,620 -t-l- 3,83t,C78 P lt A S E III E xpcnd i turc r 990 713, t 28 230,8I0 90,52{ t6l ,973 130,321 132,73{ I {30r0 Approvcd r 991 1 03 ,000 t03,000 206,000 I 75 ,500 8 l ,000 I 3 ,500 t0 ,500 5,()oo 727,500 287,000 30 ,000 220 ,000 1 5 ,000 t{0,000 t00,000 25,0oo 210,000 1 ,027 ,000 Proposrd 19 92 il 1,000 I I I ,000 I 95,000 90 ,000 t 5 ,000 t5 ,000 25 ,000 592 ,000 376 ,000 30 ,000 200 ,000 ll0,000 t00,000 t 5 ,000 350 ,000 1,2,l1,000 t- t- -t-l t- -l -t l-l t-l -l 0cP/9r . r Page 30 5.3. Biostatistics and Information Svstots Unit (BIS) ts s288,000 Data orocessing 5.3..;. The entry of entomological and epidemlologlcal evaluation data will be cont'lnued in the unit. Since important surveillance actlvities will be carried out in 1992 the volume of co'llected datawill still be high and the effort to process them wil'l be maintalned. Temporary staff will therefore have to be recruited to support the unit during the peak periods. The programmes developed in 1985 have become less effective. Emphasis v'l'll be 'laid on the updating of these prograrmes, especially as regards the processing of the entomological evaluation data. The system developed for the consultation of the surmary epidemiological data wlll be improved. Analvsis of evaluatlon data 5.3.2. The analysis of the data collected after the cessation of larviciding in the central OCP area will be contlnued. Thls analysls vill, 'in particular, cover the entomological evaluation data for which declsion making nomograms have been developed. Two years after the cessation of larv'iciding, the analysis of the epidemiological evaluation data combined with those of the entomological evaluatlon wiII serve as a basis for refining the nomograms. Another important activlty wiII be the analysis of the results obtained in the western extension where larvlcidlng and ivermectin distribution are being carried out together. The unit will continue to help the other technical units with certaln analyses as and when necessary. The preparation of reports and the presentation of the results to the OCP statutory bodies and the scientific cormunlty vill contlnue to b€ an important activity. Epidmiolosical model I lnq S.3.3. Epidemiological model I ing wi 1l play an lmportant role in the interpretation of results obtained from the surveillance of the initial Programre area after larvicidlng cessation. The study of the risk of reciudescence of onchocerciasls transmisslon wlll be lmproved by taklng into account the results obtalned during comnunity ivermectin trlals. The introduction lnto the model of parameters concernlng the new lrmunodlagnostic tools for early detection of infection and, in the case of recrudescence control, a susceptibillty analysls based on the study of appropriate surveillance strategles, wtll remain a prlority. The different trends revealed by the epidemlologlcal modelltng wtll therefore serve as references in the preparation for devolution. Finally, ln order to better quantify the impact of ivermectin on morbidity, the ocular submodel, the developnent of which has reached its full momentum, will be completed through intensive tests. Aoolled research 5.9.4. The unit will lend its support for all the stages of analysis as regards applied research. Emphasis will be laid on the lntroduction of DNA proUes for differentiating the serious form of onchocerciasls from the mild one, and on the monitoring of new lmunodlagnostlc tests. To improve ivermectln distribution, there will be a special rssearch on the crlteria for selecting vi'llages wh'ich are based on quick diagnostlc techniques. Thus, the unit wili undertake a detailed analysis of the exlsting data to identify an adequate epidemio'logical method. t l. 0cP/9r . I Page 3l OCP ccmputer netvork 5.3.5. BIS will continue to supervise, develop and maintain the OCP computer facilities. Assistance to users as well as staff trainlng will b€ pursued. The role of permanent secretarlat of the computer coordlnation group instituted in OCP will enable the unit study and put in place a medium term computer plan. Equlqnent and softvares 5.3.6. The putting in place of some equipment is necessary for the improvement of the use of data processlng in the different locatlons. Thus, 5 PS/2 computers will be bought for the Epidemiological evaluatlon unit, the coordination of entomological evaluation, the aquatic monltoring team, the Supply services, and the liaison office in Geneva. As part of the take-off of an intercountry exchange system as regards recrudsscence monitoring and control, thus contributing to the success of devolutlon, BIS has to acquire a portable PS/Z computer, model 70. These computers will be fitted with two laser prlnters, to lmprove thequality of the documents, and slmple matrix prlnters. It is planned also to provide the two operational bases of Kara and Odienne with two quick printers to accelerate the prlnting of results for the pllots. The removable storage subsystems which make lt posslble to exchange great volumes of data between the bases and the headquarters ulll be replaced and standardized because of their obsolescence. This appplles also to the flrst OCP microcomputers acquired in 1983 and the stabillzers whlch, after many repairs, are no longer functional. To meet the needs, several copies of some softwares currently being used in the OCP headquarters will be bought for the five dlfferent bases. External assistance in programning is necessary for the deve'loprnent of certain software packages. Personnel 5.3.7. A special effort has been made by the Unit to strengthen the five operational centres of the OCP ccrnputer network, by installing equipment and softwares and training an increaslng number of staff members in thelr use. The personnel requirements for 1992 are as follows: - Professional - General service - Short-term professlonal(progranmer-anaI yst) The short-term professional appears in the budget under "Consultants". In addition, the servlces of a consultant wl'll be requlreo for three months to help wlth data analysis. 5.3.8. The budget proposed for the Biostatistlcs and Informatlon Systems Unit amounts to US $288,000, i.e., a decrease of US $39,500 as compared to 1 991 I 2 1 0cP/91 . I Page 32 TABLE O EIOSIATISTICS ATO IIIFOR||ATIOII SYSIEI|S (l,s t) ,t Crtegory of erpendituru RECURREIII COSTS PEf,SOIIIIEL SERYICES Strtistician (Chicf) Strtisticirn rnrlyst Progrrmer rnrlyst Anrlyst rssistrnt ldainistrrtivo msistrnt Trrporrry rssirtrnce Sub-totrl Consu I tants Oprrrtionrl trrvel Gontncts (othrrs) 0prrrtionrl corts Sugpl ics Sub-totrl TOIAL adc0 P.5 P,I P.3 c.s G.S t-l-t-t-l-r- POSIES - - -t r 990 r 991 r 992 -l- t { 3 -t- I 3t Expcndi ture r 98C/ r 989 P H A S E III Expend i turc I 990 Approvcd I99r I 03 ,000 77,500 t3,500 13,500 -t- 200 ,877 207,500 7 {0 ,000 25C 5 2t1 r93 t5 ,000 25 ,0oo 30 ,000 5 ,000 1 5 ,000 52,993 t 20 ,000 -t- I I 253,870 | 327,500 I -l- 3C2,9?5 5 ,002 t8 ,8{8 50,969 3,732 28 , oto -t-t- t3c,6il -l-t- t99,586 Proposed r 992 t 5 ,000 llt,000 l {c ,000 000 000 5 5 80 ,000 t 2 ,000 30 ,000 5 ,000 t 5 ,000 t {2 ,000 288 ,000 -l -t- -t I -t- t- -l -t 0cP/91 . I Page 33 ts $964,0005.4. tbvolution Unit Creation of the Unit 5.4.1. The Externa'l Review of the Onchocerciasls Control Programne recomnended that a Devolution Unlt be created ln OCPr. This recomnendatlon was endorsed by the Joint Programne Conmittee. This unit, to which is attached socioeconomic development, has now been created. The role of the un'it i s: to train the nationals at all leveIs (central, intermediate, peripheral) to take over devolution activities; to promote effective participation of the national teams in theplanning, execution, supervision and evaluation of the acti vi ties; to sensitize the governments to the lmportance of taking the necessary steps for the reintegration or integration into the nationa'l structures of their nationals previously worklng in OCP; to promote information, public mobi I i zation activities; alrareness and cormunity to provide technical asslstance to the Participating Countries for the organization, strengthenlng and management of departments for the control of the major endemic diseases. 5.4.2. This nev unit will not bring aboutthe creation of addltional posts.It will be set !p through the redeployment of existing posts: twoprofessional postsl and one general service post from the Office of the Director, one professional post from the Vector Control Unlt (VCU), one professlonal post from the Epidemiological Evaluation Unit (EPI), and the professional post from Socioeconomic development. llevolution 5.4.3. It is known that the long-term success of OCP is llnked to the success of the devolution process, l.€., safeguardlng the achievement and seeing to it that recrudescence is detected in time, through a longltudinal approach to the epidemiological survelllance, and fought agalnst through ivermectln treatment. The seven Partlclpating Countries in the initial Prograrme area (Benin, Burkina Faso, C0te d'Ivoire, Ghana, l.{ali, Niger and Togo) have presented their devolution plans rhich have been adopted by the Joint Prograrme Comnittee (JPC). l{lthout ralting for flnanclng, some of these countries have already started epidemiological evaluatlon, ivermectin distribution and trainlng activitles. The year 1992 wlll b6 crucial becauseit will see the laying of landmarks with a view to the implementatlon of all the devolution plans. { Do.rr"nt JPCll.9, paragraph 48, November 1990 5 Including one short-term professional lnformation officer 0cP/91.1 Page 34 5.4.4. The Reglonal Office of the t{orld Health Organizatlon for Africa (WHO/AFRO) has created an institutional framework for devolution: appointment of a Devolution Coord'lnator based in Ouagadougou, and establishment of a Devolution Task Force composed of the I{HO/AFRO Regional Advisor on Parasitlc Diseases, the Devolution Coord'inator, a representative of OCCGE, and OCP. Furthermore, national disease prevention and control teams are belng set up. Consultat'ive meetings wi'll be held regularly between the Partlcipating Countlies, gCP and AFRO to solve devolutlon-related problems in concrete terms. Socioecononlc develoqnont S.4.5. Socioeconomic development activities ln the onchocerclasls-freed zones have been entrusted to the Oevolution unlt. The Prograrme wlll continue to play its role of liaison wlth the Partlcipating Countries and the Cormittee of Sponsoring Agencies. In addition, OCP will pursue lts actlvlties centred on the analysis of studies carried out at regional or country levelin the prograrme aiea. These studles are aimed malnly at tdentifying the sites in the onchocerciasis-freed zones most suitable for agro-pastoral production and at revieying the problems related to their development. Trainlnq S.4.6. To better establishdevolution, OCPwilI pursue ltstralnlng policy, favouring the following discipllnes: epldemiology, health services management, statistics and data processlng, health educatlon. Tralning in aIl these discipllnes will be recelved ln unlversltles and lnstltutlons ln Afrlca. Furthermore, speclal emphasls will be laid on in-service and fteld training (for example, refresher courses, semlnars, workshops). An amount of US $g1z;OOO will be requlred to contlnue to flnance fellowships already awarded whose beneficiaries are still contlnulng with their studles and to finance new fellowships and in-service training. Informatlon S.4.7 The Information Service nill continue with and strengthen its actlvitles, Iaying particular emphasls on devolution. I{ithln thls focus, informatlon campaigns will be carried out through alI available means (print media, radlo, fllms, exhibttions and lectures), almed at the general public' the Particlpatlng Countries and the donors. In collaboratlon wlth the Health Educatlon departments of the Particlpating Countries, a speclal effort will be made towards sensitization of the target populations to the devolution process ln general, and lvermectln treatment 1n partlcular. Personnel S.4.8. For the coordinatlon and executlon of the tasks of devolutlon, the Un.lt wl l l need f ive professlonals (Chief of Unlt, Entcrnologist' Epidemiologlst, Socio-economlc Development Speclalist, Information Officer) and one generat service staff member. The cost will be US $459,000' takenfully trom tfre budgets of the unlts whose personnel wlll be redeployed (as explitned 1n paragiaph 5.4.2.). An amount of US $35,000 has been added for operational travel by the personnel. 0cP/91 . r Page 35 Consultants 5.4.9. The short-term professlonal Information Officer is included th'is item. In addition, consuJtants w'll1 be used for 'l'lmlted periods when necessary. Provision is made for six man/months to this effect. under as and Budset 5.4.10. Considering the above, the budgetary requirements will amount to us $964,000. IAELE 7 OEVOLUTIOII (us t) Crtcgory of expenditure r 992 RECURREIIT COSIS PERSOIIIIEL SERYICE POSTS Chiof Devolution llcdicrl Officcr Scicntist Agro-6conori st Clerk stenogrrphor Sub totsl Conrultants ( I ) 0perationrl trrvel Operating costs Contracts (others) Fcllorshipr rnd training Sub-totr I IOIAL (ll Including thc rhort-tcru profcssionnrl in chrrgc of Infonrtion, rho rrs prrviously in the Offict of thc 0ircctor. 5 t- D I I I I I I I I Grade I I I I _l I I I I I I I I I I P.5 i P.5 i P.{ i P.{ i 0.s I I -t ttlt tt rtltltI Proposed I ll lli tee2 i lt l-l lt tl lt ttlr tt lt lt tt tt i 1il,000 ii Iil,000 iI il1,000 ii ilr,000 ii t 5,000 i ll t-l tt ttI {59,000 i tt l_-l lt tli r 36,000 iI 35,000 Ii 7,000 ii 10,000 iI 3t7,000 i tt t--l tt tti 505,000 i tt l--l lt tti 96{,000 i lt t_ t_ I I lt I t-- I I I I I I I I I I I I I -l-- I I I I It_t_ 0cP/9r.1 Page 36 5.5. Onchocerciasis ChEnotheraov Project (OCT/llacroftl) tS $2,196,000 S.5.1. The 0nchocerciasis Chemotherapy Project (OCT) will contlnue lts programne of research and development to provide a safe and effective maciofilaricide for onchocerclasis. The OCT drug development programle has now been formal'ly linked to the work of the Special Progranme for Research and Training in Troplcal Diseases (TDR) in development of a macrofllariclde for the 'lymphatic f ilariases, under the title "l,lacrofi'l Chemotherapy Proiect"(Macrofil). The neul macrofilaricidal drug development proJect is iointly financed byOCP and TDR, and wi'll be managed by the present manager of OCT. The budget outlined in table 8 represents only the OCP contributions to the Macrofil Project. The major objectives of l,lacrofil during 1992 will be: (a) To assist Ciba-Geigy ln those cllnical trlals of CGP 6140 required for a registration submission for use of this compound in onchocerclasis. (b) Once Ciba-Geigy has completed the precllnical toxlcological studles of the compound CGI 18041, Phase I clinical trials ln volunteers v'lll beinitiated, to be followed by Phase II cllnical trlals ln infected patients. (c) Compound Ul,lF 078 and its soluble salt Ul,lF 289 show parenteral and oral activities, respective'ly, in the Bruqla/dog model. Formulatlon and irritancy studies, particularly to allow intramuscular lniectlon, have been inltiated to allow the optimal route of admlnlstrat{on to be determined. Mutageniclty and toxlcological studles will proceed to allow clinical trials in man. These actlvitles vlll be carried out in collaboration with the Product Development Unit (PDU) of TDR. (d) Efforts will contlnue to obtain compounds from industry ln specific pharmacological target areas. Additional actlvity by the OCT l,lanager and the Preclinical Drug Development Team (PDDT) ln visltlng lndustrlal companies and procuring legal agreementswill be needed to maintain a flon of novel compounds. The speciflc actlvitles and resources required to carry out this prograrme of work are surmarlzed below. GIlnical trials centres 5.5.2. Year-round support for the Onchocerclasls Chemotherapy Research Centre (OCRC) at Hohoe Hospital, Ghana (Dlrector Dr K. Awadzl) vitl continue to be provlded. This centre has become increasingly lmportant, asyork on in vltro drug testlng agalnst adult 0nchocerca volvulus uorms(professor D. gitttner, Hamburg, Germany) has been transferred there from Llberia. Pharmacokinetic studies on drugs used by OCRC continue to be carrled out by Professor l,l. Orme (Liverpool, UK). If mult'icentre trials are needed for CGP 6140 or CGI 18041, addltional clinical centreswill be utillzed as required. Phase I studies in uninfected volunteers may also need to be carried out at alternatlve centres. US $415,000 has been allocated to clinlcal trials. 0cP/91 . r Page 37 Drug develoqnent rork 5.5.3. Chemical resynthesis, formulation and preclinical toxicological studies for a compound such as UtlF 078, coming from an academlc laboratory, a'll need to be done in contract laboratories to Good Laboratory Practice(GLP) and Good l.{anufacturing Practice (GMP) standards. Patenting and registration of such a compound w'ill be carried out by l{H0. At the earllest opportunity a partner from the pharmaceutlcal industry wlll be sought for codevelopment. Up to US $400,000 may be needed to develop compounds not having the support of commercial companies. Suoolv of test ccmpounds to screenins centres 5.5.4. Further legal agreements to screen compounds provlded from the pharmaceutica'l industry will be sought. This will require additlonal travel by the Project l,lanager and members of the PDDT. A company to store conpounds on behalf of l{l-10, and ship these to screening Iaboratories, has been indentified. Costs will vary according to numbers of conpounds handled, but will be approximately US $20,000. Drug screening centres 5.5.5. Primary screening ln rodent models will be carried out in two centres (Dr.t. l,lcCall, Georgla, USA and Dr S. Tovnson, St Albans, UK), wlth a third centre (Professor H. Zahner, Giessen, Germany) carrying out confirmatory testing on active compounds. Secondary screenlng of actlve compounds will be done mainly ln dogs (Dr J. McCall, Georgia, USA) and tertiary screening in primates (Dr ..1.1{. l,lark, Kuala Lumpur, },lalaysia, and Professor B. Rukmono,Indonesia), or in cattle (Professor D. Copeman, Townsville, Autralia). Costs of all animal screenlng, particularly ln the UK' have been rising due to the need for improved animal care and inflation of salaries. In vitro screening of adult Onchocerca worms nill continue, using either the human species O. volvulus (Professor D. BUttner, Hamburg, Germany and Dr S. Townson, St Albans, UK) or the cattle species 0. sutturosa (Dr S. Townson). The combined costs of running these screenlng centres supported by OCP will be approxlmate'ly US $705,500, whlle TDR will provide an additlonal US $400,000 for support of TDR screening centres. Research for targot identlftcatlon or trcde-of-actlon studles. etc 5.5.6. The Project will monltor the work going on in the general area of helmlnth chemotherapy, molecular biology and biochemistry, and support any such work of d'irect relevance to antifilarial chemotherapy. t{ork on detectlon of ivermectin resistance in nematodes will be fo]lowed closely, and lts findings app'lied to detection of posslble ivermectln reslstance ln Onchocerca as appropriate. If suitable proposa'ls are recelved, support may be glven to inmunological assays predictive of drugrinduced death of adult worms ln man and experimenta'l anlmals. US $225,000 has been allocated to these actlvltles. 0cP/91 . I Page 38 Personnel 5.5.7. One professional scientist, the Project ),lanager, asslsted by one ful]-time genera'l service secretary, will adm'inister the ilacrofil Proiect. Gonsultancies 5.S.8. The chairman of the PDDT will continue to be paid an annual sum re'lated to actual expenses and time allocated to the Macrofil Proiect (US $16,792). Short-term consultants will be utlllzed by the Proiect to establish and operate a computerized data base for drug handllng and data recording. This may require purchase of an additional computer to allow such work to proceed. Ooerational travel 5.S.9. The ProJect l,lanager will need to trave'l to aII statutory meetlngs of OCP in Quagadougou and e'lsewhere, and as noted above, travel to pharmaceutical companies may be increased ln 1992. l,lembers of the PDDT or Steering Comittee wi I I need to travel to screening centres, contract laboratories and industrial companies to carry out work requlred by l,lacrofil. A sum of US $25,000 has been allocated for this purpose. llacrofil and PDDT meetinss 5.5.10. Two Steering Comnittee meetlngs of Hacrofil will be held in 1992(tota'l of US $60,000), together with one Sclenttflc Group meeting to coordlnate the work of synthetic chemists, drug screeners and pharmacologists (US $50,000). tleetings ofthe PDDT are usually held in conJuctionwlth those of the Steering Conmittee but add'ltional meetings may be needed. The costs of all such meetings are inc'luded ln the overall estlmate of US $110'000, for consultants and temporary advisers. 0cP/91 . I Page 39 TAELE 8 OTC}IOCERCIASIS CHEI|OT}|ERTPY PROJECI (us t) P H A S E III Gradc POSTS Expendi turc r 900/ r 989 Erpcnd i turc I r 990 Approved I99r roposedP Cetrgory of cxpenditure r990ir99r r 992 r 992 -t-t-RECURREIIT COSTS PERSOIIIIEL SERYICE Sci cnti st Sccrctrry P.5 G.S 000 500 1{ 82 I 55,000 88 ,500 8ub-totrl Consul trnts, tupor!rI rdvi sers 0pcrrtionrl trrvcl Rrmrrch (othcm) 0thcr contrrcturl Services 0pcnting costs Supp I i cs llcotings (l ) 2 2 2 552,7C0 t8l,036 226,5oo t- l- 0005 050952 -l 213,500 295, t 96 c5,639 7,C81,527 6,785 I 3,532 2?0,t11 lt3,t75 18,c88 I , 308 ,1{l 7 ,8{3 1 80 ,000 20 ,000 ,2(l(} ,000 1 57 ,000 25 ,000 I , 7t5 ,500 I 0,000 Sub-totrl t02,08 n3858 5,628 1 5 ,000 I ,{53,775 I,{15,000 -t- I,C3{,811 I,C{t,500 t- T()TAL 2 2 8 ,937 ,915 -t-l- 2 2,t96,000 -t- (l) Cortr of mctingr rre included undcr 'Consultrnts, tr$orrry rdvisorr' t- - - -t-t- -t-t- -l t- l- t- 0cP/9r . I Page 40 AI}IIilISTRATIVE @STS Preliminarv note Sections 5.6., 5.7. and 5.8 concern all the costs considered to be administrative costs (see para 4.1). Each section is followed by a table based on the usual model: Tables 11, 12 and 13. The three tables are surmarized in one table, Table 14 ("0verviev of admlnistrative costs"). 5.6. Office of the Dlrector t s $727,000 5.6.1. The Office of the Director wlll be responslble for the following functions in 1992: general policy and Programne management; - liaison wlth the statutory bodles, Donors, Participatlng Countries and the scientiflc cormunity; coordinatlon of al'l Progranme actlvitles, lnc]uding research contracts and socioeconomic proJects; statutory meetlngs. Devolution activlties, which have been grouped under a ney unlt, will' as in the past, be closely l'lnked to the Office of the Director. The Documentatlon CenLre will continue to make documents available to internal and external vlsitors. In lggl , the Centre started compl I ing blbl lographies and computerized data bases. This work will be contlnued ln 1992. All documents prepared by oCP contlnue to be translated by the Office of the Dlrector. Personnel S.6.2. To carry out these duties, the Office of the Dlrector will require: - three professional staff members; one short-term professional (translation) ; slx general service staff members; - a pait-time consultant for the flnallzatlon of documents related to the PIan of operatlons for the Fourth Financial Phase. Budset 5.6.3. The proposed budget for the Offlce of the Director is US $727'000i.e., a decrease of US $S1S,500, compared to 1991, due to the_ transfer of three posts and the trainlng'budget to the Prograrme activity "Devolution". 0cP/9I . I Page 4I IAELE 9 OFFICE OF THE DIRECIOR (us t) Crtegory of expenditurc RECURRElII COSTS PERSO}IIIEL SERVICES Progrrmc Dirrctor Coordi nator Sciantist (0cncvr) Inforrrtion Officcr ( t) Adrinistrrtivc Off iccr ldri nistrrtivc lssistrnts Sccrctrry (0cncvr) Clrrk stcnogrrphrrs 0ri vrr Iraporrry strff (Scncvr) Sub-totrl Gonsu I trnts 0pcrrtionrl trrvrl Contncts (rcrviccs) 0perrting costr Suppl ics Frl lorrhips rnd trrining Sub-totrl POSTES t- - - Grade 99299990 5 I 2 I t, I I 2 .5 .5 I I 3 0.2 P.5 P.5 P.3 P.3 c.s G.S G.S G.S P 1{ A S E III ProposrdprovcdApturendErpeturcxpcndE r 986/ r 989 r99r r 992 52t,000 r 990 t- 000 000 500 000 500 000 000 ,,: tt: 83' 30' 08' 30' ,t: 000 000 000 3 t03 l{1 t 17,500 27,000 82,500 33,750 t3,500 t0,250 l- -t- 60t ,500{989r5957752 000 000 000t: 98 IO t 70,000 1t0,000 I 5 ,000 25 ,000 3t0,000 1 30 ,9{5 93,397 9,581 22 , t98 300, t0I 9r5 3r0 999 126 7{l 933 200 385 c6 r0 52 983 t I 0 ,000 2 9r0.52 I(,ITL c '81 Ic 828c26 000366 00 00 0 0 3 I 20 t2 t- I,151,326 I ,210 , 500 -t-t I I I l l I 2 I 2 I -t- -t-t t2 il0.5i 9l{,592,3r9 lll -t-t-t- -t-l -t-l-t- ttlttlttl tlrlll -t-t-t ttt trl -t-t 0cP/9r . r Page 42 5.7. Adrninistration and Suoport Services Unit ts $2,558,000 5.7.1. One of the main daily and long-term concerns of the Unlt is the need to ma'inta'in and improve cost-effectiveness. While seeing to it not to fallinto a counter-product'ive bureaucracy, controls over expenditures and comm'itments are made rigorously in the whole Programe area. The management of personnel, equipment and vehicles follows.a series of strict rules but does not exclude adaptation to necessities and to the evolutlon of activities. In playing its role, the Administration, which has its own exigencies, does not lose sight of the fact that it is at the service of the technical and operationa'l activities. Basic management principles are 'lncreasingly supporting the activitles of the Administratlon Unlt whlch 1s striving to disseminate them throughout the Progranme area, particularly through the organization of seminars and the preparatlon of a practical handbook. Data processing, which has been in use ln the financial services since 1988, is being app'lied'ln many ways ln the fields of personnel and suppl'ies, and is currently being introduced in the management of vehicle spare parts. Personnel 5.7.2. The staff requirements for the administratlve and managerial dutles are as follows: - Professionals - General service staff 6 85 This represents a decrease of one professional post compared to 1991. Consultants 5.7.3. A short-term professional, based in Ouagadougou, vill continue to provide the necessary support and guidance to the officers responslble for administrative and managerial activities in the western extension so as to hetp them have control over their duties, particularly in the flnancial f teld. Budqet 5.7.4. The proposed budget for 1992 amounts to US 02,558,000, whlch represents a decrease of US $127'500 compared to 1991. 0cP/91 . I Page 43 TASLE IO AOIII}IISTRATIO}I AilD SUPPORT SERYICES (tJs t) Crtegory of cxpcnditurc RECURREIIT COSIS PERSOIIIIEL SERVICES Chicf Adrinistrrtion I llrnrgrrlnt Adri nistrrtion Off iccr Budget and Finrncc 0fficer Trlnsportrtion I Com. Officcr Supply rnd Scrviccs Officcr Supply rnd Srrviccs Officcr Finrncc Officer Adri ni strrti ve 0f f i ccr/Burko Prrsonncl Officcr Pcrsonnel Officcr Adrinistrrtivc end Tcchnicrl rse i strnts Clcrks/typists t storckccpcrs Drivcrs, mssengr16 rnd ltbourers Tr$orrry stlff Sub-totrl Consu I trnts ODcrrtionrl trrvcl Scrvicc contnct6 0pcrrtionrl costs tuppl irs Sub-totrl adeGr t- 6 5 { I I 3 3 3 3 2 G.S G.S 8.S TOIIL -l-t-t- I ,937 , 0{9 2 ,532 ,698 2 , C85 ,500 POSTS 990 r99r 92I t{ 16 28 It {6 28 90 90 -t-r-t-t-96 96 9 P ll A S E III turcExpend 989986I ureExpendi t r 990 Approved t99r 103,000 t03,000 t03,000 t 03,000 1 03,000 500 500 lt n 77,500 t 89 ,000 62 1 ,000 378 ,000 30 ,000 6 , 323, 329 I ,880,253 , go5,5oo t73,t78 {76,308 {5,197 I,319,00c c00,27t {9,9t3 t07,08{ fi,009 380,8{3 73,596 55 ,000 1 30 ,000 35 , o0o 350 ,000 150,000 320l{c2 il52c 5 00t20 0 -t- dr0p08eP r 992 lll,000 I I I ,000 I I t ,000 2t0,000 675 ,000 390 ,000 1 0 ,000 500 00 83' 83,5 000 000 000 000 000 55 20 32 50 ,000 r05 206 00089 3 -l 2 ,550 ,000 -t -t- -t-t- I I I I I I I I I Iti I Ilititi I Iti I I .lll I I I IIr i{5i 26i I I I I I et I I -l I I I I I I I I I I I t I -l -t- -t-t-t-t -t- -l I I I I I I I I I I ril,000 i t- -t 0cP/91 . r Page 44 5. 8. Administrative support-]rr_lgogyg us $340,000 5.8. l. i{HO Headquarters wt I I continue to provicje administrative support to the Programme in a series of fie'lds which cannot be covered separately in Ouagacjougou: saiaries, ai iowances, pension and insurance, personne) admin'istration, medical services, central procurement of suppl ies and equ r pment. 5.8.2. For these services, i{H0 is authorized to charge OCP 13X budget of the Programme (since it is a programme supported from budgetary sources). This wou ld have meant, for OCP, an of US $4,219,000. However, t{HO Headquarters charges OCP only on recoverable basis, i.e., an amount of approximately US $340,000. IAELE I I ADI{IIIISTRATIVE StJPPORT GEIEYA (US I) r990 r99r r 992 Clerical assistrnce Finance, Personnel Supp I y 290,000 of the ext ra- amount a cost I 9898 0738I 271,617 902 000 ----_- | 0perEtr ng cost Supp I i es 25 57, IO 28 u 0 00 00 35,000 3 0 0 00 5 3r0 000 000 0 TALIO I,021,06? I3 2 003{ 00 ---l I { I r5, 0cP/9r . r Page 45 TABLE 12 AOIIIIIISTRATIYE COSTS . COIISOLIDATEO IABLE (us t) Crtcgory of expcnditure RECURREIII COSTS PERSOIIIIEL SERVICES Progrrme Dircctor Ghicf tdrinistrrtion t lhnlgtmnt Coord i nrtor ldri nistrrtive Off iccr Scientist (Gcnsvr) Budget I Financc Officcr Irrnsportrtion I Com. Officcr Supply rnd Srrviccs Officcr Finucc Officcr tdainistntive Offimr Adri nirtrrti ve Off i ctr/lurko Pcrsonncl Officer Pcroonncl Officcr ldrinistrativc rnd Technicrl res i strnto Sccrctrry (Gcncvr) Glcrk stcnogrrphcrr Gl crkt/typi sts/storckccpers 0rivrrr, $ssrngcrs rnd hbourrrs Ic4orrry rtrff (Gcncvr) Irrporrry strff ldrinirtrrtivc Support costs - 0cncvr Sub-totrl Conrul trnts 0prrrtionrl trrvol Scrvico contrrcts(lprrrtionrl cootr Suppl i cs Frllorrhigr rnd trrining (l) Sub-totrl TOIAT rdc 0.2 P.6 P.5 P.5 P.5 P,t P.{ P.t P.3 P.3 P.3 P.3 P,2 G 6 G G G I90 5 5 r6 I 3 {0 29 -t- -t- r08 08 POSIS 99 ; r0 I 2.5 r0 29 r06.5 0c 5 (l) Crtcgory of crpcnditurc trrnrfcrrcd to Dcvolution unit in tgg2 l{,551,030 3, 625 ,000 r 992 I l r0 I 2 {5 2l 00 -t- -l- r00 -l- Erpendi ture r 900/ r 989 -l- 08020 t!0,393 8Cl,Ct8 il2,190 I ,359 , 7ge 053,0t2 983, 933 I 9r{,130 P }l A S E III Erpend i ture r 990 I ,l{6132 tg0,85g 200, t8 t {t ,009 123,tlt il t,09t 30c , t07 t,009, {t 9 dproYeAp r99r il3,000 1 03 ,000 t03,000 1 03,000 tlt,000 1 03 ,000 t03,000 t03,000 77 ,500 77,500 77 ,500 77,500 2t0,000 82,500 33, I50 621,000 391,500 t0,250 30 , o0o 290 ,000 0000862 -l- 225 ,000 2t0,000 35 ,000 {00 ,000 t 90 ,000 3t6,000 -t- I I t,266,273 | I,t06,000 I -t- t , 2c0 ,000 -l- oposedP r 992 1 55 ,000 il 1 ,000 il t ,000 fi1,000 g3,500 83, 500 I 22 ,000 il1,000 I 0 ,000 290 , oo0 83 500 000 500 000 000 000 2r0 88 30 075 r05 2 0007r -l t 53 ,000 1 90,000 32 , ol)0 395 ,000 ils,000 00059 s E s s s I I I I I 1 t I t t : I -t- -t- -l- I -t- -t- I I lt0,l I -t- t- l-t t-l t-t 0cP/9r . r Page 46 5, 9. Statutorv npetinEs ts f305,000 5.9.1. The meetlngs planned for 1992 are: - the Ecologlcal Group - the Expert Advisory Conrnittee - three sessions of the Conmitte of Sponsoring Agencles - the Joint Programe Cormittee The budgetary provision covers the costs of travel and per dlem, temporary assistance, translatlon of documents, interpretatlon services and various supplies. One full-time administrative offlcer and a secretary working part- time, budgeted for withln the Office of the Director, are employed for the organization of meetlngs. 5.9.2. The National 0nchocerclasis Comnittees hold a technical meeting of nationa'l experts every year under the coordination of the Programne Director. The 1992 meeting will be held in Ouagadougou. Although, technically, this meeting is not a statutory meetlng, lts costs secretarlat and interpretation services - are included in this Progranme activity. 5.9.3. The costs of the participation of non-OCP experts in OCP meetings other than the above (research, ivermectin distribution, hydrology' hydrobiology, etc.) have been included in the "Operatlonal travel" category of the budgets of the host units. 5.9.4. The budget proposed for this Programme actlvity is estlmated at US $305,000, .|.e., the same as that approved for 1991. 0cP/9I . I Page 47 TABLE I3 STAIUTORY I|EETIIICS (lJs t) Exprndi turr Erpcndi turc I 990 Approvcd r99r Proposed Crtcgory of cxpcnditurr 989e8c/ r 992 RECURRE}II COSTS PERSOII}IEL SERYICES Tcrponry rmirtrncc -l- {5 ,000 -t- t5 ,000 {5 ,000 Sub-totrl Consultrnts/Ilrporrry rdviscrs 0prrrtionrl trrvel Oprrrting costs Contrrcts/Irrnsl rti on Supp I i cs Sub-total 5C ,559 -t- I6 t5,000 313,0t8 350,3{3 I 9,105 I 7 ,567 206,8?2 088 3{8 02r 826 It0 105 6 I t 35 ,000 1t0,000 t 0 ,000 5,000 35 000 000 000 000 0 0 5 35907 2 c2g532 2C0 ,000 000 000 260 305TOIAT I ,023,353 -t- 309 ,0{5 305 ,000 -l- t- l-l -t t-l t- t-l -t- t l- 0cP/9r . r Page 48 5.10. Caoltal costs ts $907,000 Office equiment 5.10.1 This mainly concerns replacement furniture. The cost remains the same compared to 1991, 1.e., US $25,000. Data orocessino eouimpnt 5.10.2. Five centres have been provided with data processing equlpment: Ouagadougou, Bamako, Odienne, Bouake, Kara, and portable ccrnputers are also being used. The cumulative lncrease of data from one year to the other, the instal lation of stl l'l more complex and high-performance programes, the 'increased need for exchange of intercountry data between the various OCP centres and the outside world, and finally the obsolescence of part of the equipment acqulred in 1983, have necessitated the purchase of new equlpment. The total amount requlred is US $77,000, .l.e., an lncrease of US $22,500 compared to 1991. Details of the requlrements are to be found under the Programne activity "Blostatlstics and Informatlon Systems Unit". Technical eouiqmnt 5.10.3. This concerns the purchase, installatlon, replacement ormalntenance of various items: hydrology (beacons, water-gauges, batterles, solar panels), electrlc Aenerators, research (mini-gutters, susceptlbility tests), optical equipment. It is planned to spend US $198,000, .|.6., a decrease of US $12,000 compared to 1991. Vehicles 5.10.4. The OCP fleet, distributed in the whole Progranme area, comprises 336 vehicles, i.e., 206 for the tnltial area and southern extension, and 130 for the western extension. Llke every year, vehicle requirements have been reviewed and, for 1992, it will be possible to reduce the total number to 320. For replacement vehicles, totalling 29, an amount of US $ 597,000 vll'l be requlred, i.€., a decrease of US $ 53,000 compared to 1991. The evolution of the number of Prograrme vehicles from 1982 to 1992 ts glven in Annex X. Bul ldlnqs 5.'t0.5. No new buildlng rtll be constructed in 1992. An amount of US $10,000, which {s the same compared to 1991, is requlred for the improvement of the infrastructure. 0cP/9r . r Page 49 TABLE 11 CAPITAL COSIS (us t) Expend i ture r 986/ r 909 5982 l- tureErpcnd Approvcd poscdPro 000 1 990 r99t r 992 Officc furniture (l) Drta proccssing rquiprcnt (l) Uchiclcs Equipmnt Euilding 2 6t,587 25 ,000 2 58,81t I , 719 ,839 I ,955 , gg3 550,717 52,2t5 702 ,855 221 ,58 t t5,589 5{ 650 2r0 l0 500 000 000 000 77 ,000 597 ,000 t 98 ,000 1 0 ,000 TOIAL { , {27 ,988 t ,086 ,857 9{9,500 907 ,000 (l) During 1980 to 1988, the rcquisitions of drtr proccssing rquipacnt rcrc chrrgrd to Office Furniturc IAELE I5 EREATDOTII OF CAPIIAL COSTS TO ICTIVIIIES (us t) Off i cc 0rtr proccss i ng cEuipmnt Ychiclc prrntEqu l 8u d n9 000 TOTAL i turcFurn -t- l- 9{ l- 00090 t-t Icctor Control Epi dcri ol ogi crl Evrl urt i on 0iortrtistim rnd Inforntion systlis Progrrrrc Dircctor Adrinietrrtion rnd support Scrvices 0 000 000 000 000 2t ,000 I 00010 000 000 0 82 ,0006 21 I 5 2 1 000 000 000 000 15 ,000 55 ,000 1 ,000 ,000 ,000 22, 7, 7 ,00 -t- I I 25,ooo I 77,000 I 0 20 ,000 99 ,000 TOIAL 98 0 I597 ,000 000 000 -t- -t- -t- 1 I i)a 2 9F .E oAOz GF J Irlz z ooG trl G zIF GF o = =o 0cP/9r . r Page 50 ANNEX I Fu, uf 5H(J6 o ar UJIz o0 oF u, zol!J 4 a( -uro lr,l =D(, o lrJo9g> JGO. lrlL]A?3 oIu >zlrl <0z 3Eo I t., F s3AErl sa6<lr z z ut .o JOA<zaE9<urF- l( l{ G o lU =E EOr- E=J(JOrFAf- -G1arq \J'\J-OE cfr9= =<Hg u6 o - I oz o (,6z99gs o)JF<z>ul! o oJo .Eo I <,ur<Zo =6cto J 0 Irl tg v, ozo - lrli=2atsuro.o<oo -FJO <ur -, =I F s3ifEod2 lr F U' trl uiFr 3E o :o a( uJ 9 st =965 trg oo +0<z <u, l!Fcx <ur JZ<czu6F lEfoo o lrl4 zG lrJF o ul alrl9 a,t{o Ft oa o' =6 oz z 9F EFI =-o zo F F - u, - ,() oo 60 =IrIt! = z 9FD 0 l{o (( x I oY- =dE9Iloi H,i3 fi I6o 3< ur o=G roo troFo= H86I urY =EES 8o E,A z 9ozl!F x trJ zr lrJFo lr,l] ooEZw<F o?ei o1 -9F- dFF< oZOGae = oY - 6 lrloE<E>og 6!*o- 3J a, c,lrl -F =(,;srsOI.Eoo. o -oz o J Or oootr ds E3Eu lrt 5 o of oo C' f o t! G z a( trJF0 lr,l! UJ(E J I G o J o arFz o(, E oF(, lrl 0cP/9r . r Page 5I ANI{EX I I E -Y=LOgE .EE .EE =troooo <X u) E eEg F.g '-.=(/)f^oaa =ocEEEEuro. r+o o tO o(ooNo@oooo F C) F F oN F o c, F ot l. olo F Lb,E tL Gt,Ae,;-s38 o) @ o) Fr o @o l- No o) F (o @o F rO @ o) F to o) (t, @o F cl @ o) F E JJoo ul.'.qLJG UJE I.-rlFOtrEo5 Us ,=G-<i IG'O= ils lL-o oluF E eler e6ueqcxa Z961 1o e6eluacred 0cP/91.1 Page 52 AI{I{EX III Staff Guaranteed hel lcopter hours Excess helicopter hours Guaranteed fixed-wing aircraft hours Excess fixed-w'lng alrcraft hours Guaranteed Liaison alrcraft hours Excess liaison aircraft hours Insecticides Cost per lltre B.t. lFl4 Temephos 20f EC Permethrln 20r EC Carbosulfan 25I EC Pyraclofos 50I EC Phoxlm Value of US dollar CFA Franc French Franc Svlss Franc Pound Sterllng Deutschmark Canadian Dollar Japanese Yen AVERAGE CTXiTS I'SED FOR BI'DGETARY CALCULATIO'S 1 990 us$ 1$ 99 US 1 992 us$ Professional D2 P6 - P4 Ouagadougou Geneva P3-Pl General Service - others General Service,/OCP Geneva Consu I tant,/month Temporary General Service/month Note: The above estimates lnclude gross salaries, post adjustments, allowances and grants, OCP's share of pension plan (15,8I) and medical insurance (2r51),per diem for consultants, medical evacuatlons, any other emoluments provided for in the staff rules. AerlaI Ooerat'lons Cost per flvinq hour (incl. fuel) 000 000 000 500 000 500 000 900 122 111 155 83 15 88 8 000 000 000 500 500 500 700 900 113 103 144 77 13 82 7 000 000 000 000 500 000 000 800 05 95 28 t0 11 75 7 1 1990 us$ 853 742 869 758 248 124 1991 us$ 853 742 869 758 248 124 I 992 US$ 853 742 869 758 248 124 Cost (CIF) 1 990 us$ 1 992us$ 4,81 11,96 9,05 21,75 27,11 Budoet 90 Budqet 91 Budqet 92 99I US 1 $ 3 2 II 1 1 I '50 '60 ,20 40 0025 4 4 0 I 1 20 26 17 64 13 64 59 45 05 68 47 60 68 18 5 5 1 0 1 1 28338 6. 76 1 .75 0. 638 1 .99 1.20 140 852 68 .47 5 1 0 1 1 149 .60 .68 .18 1 49 I 1 , , t t0cP/9r . r Page 53 ANNEX IV NUMBER AND PERCENTAGE OF OCP STAFF MEMBERS BY SEX AND NATIONALITY As at 3l May l99l NATIONALITY PROFESSIONALS GENERAL SERVICES Male Female Total % Total Male Female Total % Total ALGERIA 0 0 0 0.00 0 I I 0.20 BELGIUM I 0 I 2.78 0 0 0 0.00 BENIN I 0 I 2.78 53 I 54 t0.t4 BURKINA FASO 5 0 5 13.87 135 20 155 30.81 CONGO I 0 I 2.78 0 0 0 0.00 COTE D'IVOIRE 3 0 3 8.33 9l I 92 t8.29 FRANCE 2 0 2 5.56 0 I I 0.20 GAMBIA I 0 I 2.78 0 0 0 0.00 GERMANY I 0 I 2.78 0 0 0 0.00 GHANA 5 0 5 13.89 64 I 65 t2.92 MADAGASCAR 0 I I 2.7E 0 0 0 0.00 MALI 4 0 4 I I ll 67 3 70 13.92 NIGER 0 0 0 0.00 7 0 7 1.39 SENEGAL 2 0 2 5.56 0 0 0 0.00 TOGO 3 0 3 8.33 56 0 56 I l.l3 UNITED KINGDOM 3 0 3 8.33 0 2 2 0.40 USA I I 2 5.56 0 0 0 0.00 VENEZUELA I 0 I 2.78 0 0 0 0.00 TOTAL 34 2 36 r00.00 473 30 503 r00.00 a 0cP/91 . I Page 54 At{t{Ex v $lL Eg L oFtotro)-g Go oo o, F o, @o l. @ @ o) F F @ o, F (o o o) F 1l) @ CD F t @ o, F (D @ o) F ot @o Na cta NIt oFIt N|o n q to |o u, c, u) |o .g ct(o F o lOF lo u) loF r0 o co NID ao to c, .O q ro GD F (l,(o F NNlr o) o! o a o o, o c, fo o(J o3oL o ofo o o. rts o L o .Cl E)z 0t o) o) F oF N @ o) F =oEll @ ulI E ut U' J UJzzoa E, IJJ o- ILo F ctt oo q or 4D o3 bo otreeo=9PEoo o.=o.-9 o EEEEpB -o oJi EEHEEa LLEo6rElt.ooEEg330, =zL mHl oo ot o$o(ooo F rolo o6l F ot F c)(o F o @ F ooN s r o ! ante^ 286 ! lo ooeluaclad 0cP/9r . r Page 55 ANNEX VI G Ut 3EEo -trEOg= l!E E.s E-oP6 IN Hi F L(E z, oooGFc) o o) o) F o) @ o, F @ @ o) F r\ @o F (o @ o) F 1() @ o) F $ @ o) t- (t, @ o) F GI @ o, F g) G) G, f- c, cl,oIDta o)ooF c,oF la ro rO ro NN T\ c,(o rt o, o c,oo o(!, o o,(ooF (otoF oto .!,o lo c? u) u)|o F,(o o(o y o oo ,t2 oLo oL J o I +,s o) =lr $t o)o F oF $t @ o) l- =oE lJ. @zI F- E, IU o-o J E, IJJ t i a q t ooooooooooOO(orfNOO@t$l NFFFFF Q G, , o enle^ 286 ! lo eoeluecJad : 9i l -{ 'G :l 'I U (, z I I J l ) \ ,)(. J o 'o,!.=or0 o-(,!E L,Oo.- ii at (, EE9 Eb sE ;d 6EE; EE oq, tstb; P:O I Ot.:go.E 9.9 -O tu.=F o, -.SEE Eg t3t:t: i 2o z t)o La a aEa tr) o J / 0cP/91 . I Page 56 ,>5\(,Etil. **w N o o (r f, o(L Lu @ oL o(r(L f c) UJo @zIF trtJ lrJH8 9'otrl Z ZJ IAruJ o)zo z oL q zo tr G UJLo Lo z J(L f,o o UJa o 0- o(ts & a't I tr \ 0cP/9I . I Page 57 ANNEX VIII I I a INITIAL AREA Countrv - C6te d'Ivoire Mali VYESTERN EXTENSION Countrv Guinea Mali Sierra I-eone Secteur Kankan Faranah (Supervision, HQ WOA) Makeni Operational base VCU ET{TOMOLOGICAL EVALUATION NETWORK - 1991 Western ooerational area WOA - Bamako. Mali Sector Sub-Sector Bouake (*) Korhogo Odienne Seguela (Supervision, HQ WOA) Bamako 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. Kankan Siguiri Beyla Kerouane Kouroussa Faranah Dabola Kissidougou Mamou Sikasso Makeni Kabala Bo Eastern Operational area EOA Kara. Togo INITIAL AREA + SOUTHERN E)MENSION Country Sector Burkina-Faso (Supervision, HQ Ouaga) Sub-Sector Bobo-Dioulasso Ouagadougou 0cP/91 . I Page 58 ANNEX VIII (cont'd) COte d'Ivoire (Supervision Bouake) Bouake Bondoukou Togo Kara Kara Atakpame B6nin Parakou Parakou Bohicon Kandi Natitingou Ghana Tamale Tamale Kintampo Hohoe Bolgatanga (-) As a result of the new delimitation of area, the sector of Bouake remains in the Western Area but its sub-sectors have been shared between the West and the East. I ,a a I o a J , I : o q t at o t ( lol iar lllr f q, c =(,(l, E o .; c C, E o E oE vt a, -cgO .EIt' g) o9L.U :98 ci eblts 'o;E!-sCo= -o (,i, .tr :.,utz \ 0cP/91 . I Page 59 E AililEX IX i \l sI t\ (o .. 'l I I I I I I I I I N U} c o ll PEE-cxbo OoOE og EEgf .-\F> JO ..! >, €8 cl,'JCOO .oa o-5(); OUJ tili I1 9 € G ! E :l : og z oI I tJTL E 6 \t!! l.J 9) I t t I I i a G Itlr- su9QT trJfIE tL 9 EL .a \ e\\(] ., I aa o I L x a o \ t I t J a B t I t o t, I #-\ I\ I I t t t- -r b ,s l.r ) t !' t I I lna I( I t \J a I \ N trJooaz >E19 F<zw trJ Z =trk8 HE F. UJ z>Ft-QZ lrJ U.t ==(E trJUJF>a E 3F <G(J:)(/)o UJL(9$t(ro)je l!ZO lrJ 93)ll.J -6dNg o- EzoN q I ! tr,JJ trJI(J lrJ a , \ ,I \ l+ \ , I I a :T I , ocP/91.1 Page 6O ANNEf, X L Go L Gt,tr .9 Go N o, o) F o)o F o o) o) F o, @ o, F @o o) F r\ @ o) F @oo F loo o) F $ @ o) F (D @ o, F N @g) F NloN o) r\N N]\N NoN o(\t a) o F c) tN(D (o G' a) ot c) @$o (o lo(D zIl- E, UJGONZEI F utoUJFd$ - - - IFuJ= IL ]Lo E, UJo = =z oooooocrooooooootGTNFC)o)ON(OlOt(')NF FFFF ? t ,. anlB^ 286 t lo e6Btuecrad