Polio Bulletin Week 52, 2011 (as of 30 Oct 2012) Table 1. Classification of AFP cases with onset in 2011 and key surveillance indicators 2010 Classification Reported number of cases Expected number of cases Reported number of cases Confirmed Polio Poliocompatible Non-polio (Discarded) Pending
2011 Indicators % Non-polio % cases with % reported % with follow inadequate AFP rate per 2 specimens within 14 stools with up 100,000 < 15 within 14 days of onset follow-up days of onset yrs Pending classification > 90 days after onset
Latest report date 12-Jun-12 05-Jul-12 03-Apr-12 12-Apr-12 29-Feb-12 07-Jun-12 16-Jan-12 23-Mar-12 02-Mar-12 02-Mar-12 27-Oct-12 27-Jan-12 27-Jul-12 13-Mar-12 10-Jan-12 10-Mar-12
Australia Brunei Darussalam Cambodia China Hong Kong (China) Japan Lao PDR Macao (China) Malaysia Mongolia New Zealand Pacific island countries Papua New Guinea Philippines Republic of Korea Singapore Viet Nam Western Pacific Region
43 2 44 5,285 14 0 41 1 124 19 7 13 17 413 70 4 304 6,401
42 1 55 2,225 8 167 24 1 77 8 9 9 28 364 78 6 226 3,328
61 3 75 6,182 15 0 43 1 129 11 3 9 10 335 32 4 390 7,303
0 0 0 21 0 0 0 0 0 0 0 0 0 0 0 0 21
1 0 0 15 0 0 0 0 0 0 2 0 1 0 0 0 19
60 3 75 6,146 15 43 1 129 11 3 7 10 334 32 4 390 7,263
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1.45 3.00 1.36 2.78 1.88 1.79 1.00 1.68 1.38 0.33 1.00 0.36 0.92 0.41 0.67 1.73 2.19
34% 100% 89% 92% 93% 72% 0% 78% 100% 33% 22% 50% 67% 69% 100% 97% 90%
69% 100% 96% 95% 87% 81% 100% 92% 91% 67% 33% 70% 88% 44% 75% 90% 93%
0% 100% 100% 99% 100% 100% 100% 100% 100% 100% 89% 100% 23% 100% 100% 97% 95%
0% 100% 96% 100% 100% 100% 100% 100% 86% 100% 19% 100% 100% 79%
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
* Follow-up is not required by the Polio Expert Committee if a case can be classified as non-polio AFP on the information available ** Polio due to importation; includes eleven cases > 15 years old. Further details may be read on the following webpage: http://www.wpro.who.int/entity/immunization/news/wild_poliovirus_China/en/index.html
Chart 1. Non-polio AFP rate per country, 2009-2011 3.0 2.5 Non-polio AFP rate 2.0 1.5 1.0 0.5 0.0 CAM CHN LAO MAA MOG PNG PHL VTN 2009 2010 2011
Chart 2. Percent cases with adequate specimens, 2009-2011 100% % cases with adequate specimens 80% 60% 40% 20% 0% CAM CHN LAO MAA MOG PNG PHL VTN
2009
2010
2011
Polio Bulletin Week 52, 2011 (as of 30 Oct 2012) Table 2. Laboratory investigation of AFP cases with onset in 2011 National reference lab Total no. of AFP cases with specimens Processed by old algorithm AFP cases with specimens Lab results P1 P2 P3 Polio Mix Polio/NPEV NPEV only Negative Pending results ≤ 28 days > 28 days % results reported within 28 days AFP cases with specimens Processed by new algorithm Lab results L20B+ L20B+ +NPEV NPEV only Negative Pending results ≤ 14 days > 14 days % results reported within 14 days % positive for NPEV Latest report date Country
Australia Brunei Darussalam Cambodia China China, Anhui China, Beijing China, Chongqing China, Fujian China, Gansu China, Guangdong China, Guangxi China, Guizhou China, Hainan China, Hebei China, Heilongjiang China, Henan China, Hubei China, Hunan China, Jiangsu China, Jiangxi China, Jilin China, Liaoning China, Neimongol China, Ningxia China, Qinghai China, Shaanxi China, Shandong China, Shanghai China, Shanxi China, Sichuan China, Tianjin China, Tibet China, Xinjiang China, Yunnan China, Zhejiang Hong Kong (China) Lao PDR Macao (China) Malaysia Mongolia New Zealand Pacific island countries Papua New Guinea Philippines Republic of Korea Singapore Viet Nam, North Viet Nam, South Total
VIDRL VIDRL NIID Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab Prov. Lab PHLC NIID PHLC IMR, KL PHI IESR VIDRL VIDRL RITM NIH SGH NIHE PI
37 3 76 6145 334 30 66 176 109 424 266 198 49 453 121 698 269 343 304 186 70 129 74 34 25 133 395 31 197 381 23 11 166 259 191 15 43 0 144 12 3 10 9 380 32 4 194 189 7,296
6145 334 30 66 176 109 424 266 198 49 453 121 698 269 343 304 186 70 129 74 34 25 133 395 31 197 381 23 11 166 259 191 6,145
62 2 0 0 2 0 5 2 1 0 0 0 1 5 1 11 0 0 2 0 1 0 1 2 1 1 1 0 0 20 3 0 62
50 1 0 0 3 3 3 1 4 1 2 0 4 0 3 4 2 0 1 0 0 0 0 4 0 1 6 0 0 2 2 3 50
53 4 0 1 1 3 11 1 2 0 5 0 2 0 0 0 1 0 1 1 1 0 2 6 0 0 1 0 0 4 3 3 53
28 2 0 2 0 0 7 4 2 1 1 0 2 0 1 0 0 0 0 0 0 0 1 1 0 0 1 0 0 1 1 1 28
12 1 0 0 1 0 1 0 0 0 0 0 1 0 0 0 1 0 1 0 0 0 0 1 0 0 0 0 0 5 0 0 12
779 51 4 8 13 13 69 28 23 18 71 12 140 33 41 10 27 11 12 3 3 3 19 38 0 22 47 4 0 6 31 19 779
5124 273 26 52 156 89 326 230 164 29 373 106 545 229 295 279 153 59 111 68 29 22 109 341 30 173 325 18 9 122 218 165 5,124
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
97% 99% 100% 100% 99% 99% 99% 99% 100% 92% 98% 100% 97% 97% 99% 96% 100% 100% 99% 96% 90% 100% 100% 94% 100% 94% 94% 100% 60% 83% 100% 98% 97%
37 3 76 15 43 144 12 3 10 9 380 32 4 194 189 1,151
0 1 1 0 4 0 0 0 0 1 0 0 0 1 2 10
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 0 18 0 10 5 3 0 1 3 36 0 0 12 19 108
36 2 57 15 29 139 9 3 9 5 344 32 4 181 168 1,033
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
100% 100% 95% 90% 91% 90% 100% 100% 100% 100% 96% 100% 100% 98% 100% 96%
3% 0% 20% 11% 12% 12% 9% 7% 9% 13% 9% 11% 33% 13% 7% 17% 12% 11% 3% 12% 16% 8% 3% 9% 10% 9% 8% 0% 9% 12% 11% 0% 7% 9% 9% 0% 19% 3% 25% 0% 6% 28% 7% 0% 0% 5% 10% 10%
05-Oct-12 30-Jan-12 30-Jan-12 12-Apr-12
17-Jan-12 24-Jan-12 17-Jan-12 09-Feb-12 08-Feb-12 12-Jan-12 01-Feb-12 30-Jan-12 19-Jun-12 20-Feb-12 20-Jan-12 11-Apr-12 18-Jan-12
Acronyms: IESR - Institute of Environmental Science and Research, New Zealand IMR, KL - Institute of Medical Research, Kuala Lumpur, Malaysia NIH - National Institute of Health, Seoul, Republic of Korea
NIHE - National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam NIID - National Institute of Infectious Diseases, Japan PHI - Public Health Institute, Mongolia
PHLC - Public Health Laboratory Center, Hong Kong (China) PI - Pasteur Institute, Ho Chi Minh, Viet Nam RITM - Research Institute for Tropical Medicine, Philippines
SGH - Singapore General Hospital, Singapore VIDRL - Victorian Infectious Diseases Reference Laboratory, Australia
Polio Bulletin Week 52, 2011 (as of 30 Oct 2012) Table 3. Intratypic differentiation of polio isolates from AFP cases with onset in 2011 Country Intratypic differentiation lab1 AFP cases with polio isolates ITD results2 P1S P1W P2S P2W P3S P3W Pending3 Discordant4 ITD Sequencing results VDPV Not VDPV Pending % ITD results % ITD results % ITD results within 7 days within 45 days within 60 days of receipt of onset of onset
China Hong Kong (China) Macao (China) Malaysia New Zealand Singapore Australia Brunei Darussalam Pacific island countries Papua New Guinea Philippines Japan Cambodia Lao PDR Mongolia Republic of Korea Viet Nam Total
CCDC PHLC PHLC IMR, KL IESR SGH VIDRL VIDRL VIDRL VIDRL VIDRL NIID NIID NIID NIID NIID NIID
227 0 0 0 0 0 0 1 0 0 0 0 1 4 0 0 3 236
71 1 0 2 1 75
21* 0 0 0 0 21
79 1 0 3 1 84
0 0 0 0 0 0
91 1 1 2 1 96
0 0 0 0 0 0
0 0 0 0 0 0
0 0 0 0 0 0
6** 6
0 0
0 0
96% 100% 50% 67% 67% 94%
53% 100% 0% 67% 100% 54%
84% 100% 100% 100% 100% 85%
* Includes eleven cases > 15 years old **One type 1, four type 2 and one type 3 VDPV
Table 4. Laboratory investigation of polio isolates from non-AFP cases in 20115 Country Intratypic differentiation Polio isolates lab ITD results P1S P1W P2S P2W P3S P3W Pending Discordant Sequencing results VDPV Pending
China Hong Kong (China) Macao (China) Malaysia New Zealand Singapore Australia Brunei Darussalam Pacific island countries Papua New Guinea Philippines Japan Cambodia Lao PDR Mongolia Republic of Korea Viet Nam Total 1
CCDC PHLC PHLC IMR, KL IESR SGH VIDRL VIDRL VIDRL VIDRL VIDRL NIID NIID NIID NIID NIID NIID
162 4 0 3 0 0 0 0 0 0 1 0 0 0 1 0 0 171
59 0 2 1 1 63
30 0 0 0 0 30
19 4 0 0 0 23
0 0 0 0 0 0
54 0 1 0 0 55
0 0 0 0 0 0
0 0 0 0 0 0
0 0 0 0 0 0
3*** 3
0
*** All type 2 VDPV Acronyms: CCDC - Chinese Center for Disease Control and Prevention, China IESR - Institute of Environmental Science and Research, New Zealand IMR, KL - Institute of Medical Research, Kuala Lumpur, Malaysia NIID - National Institute of Infectious Diseases, Japan PHLC - Public Health Laboratory Center, Hong Kong (China) SGH - Singapore General Hospital, Singapore VIDRL - Victorian Infectious Diseases Reference Laboratory, Australia 2
ITD Results : S - Sabin; W - Wild 3
4
Antigenic ITD <> molecular ITD for all serotypes. Cases with discordant ITD results may be counted more than once under "ITD results", ie. as "discordant" and "S" or "W" or "VDPV", depending on the results of sequencing. 5
Pending ITD = Pending antigenic ITD and/or pending molecular ITD; Total pending cases = Pending ITD + pending sequencing
Based on year of collection of sample, if available. Otherwise, based on year of receipt at reference laboratory.