א / EB128/4
א
/
:
.(
)
/
:
EB128/4
ANNEX
/
:
( .(
)
. ( ) ) .
:
( (
(
)
)
/
: . ( ) ( ) )
:
(
)
.
.
.
. ( )
/
. : () . /
.
3
EB128/4
Annex
/
( ) : .
.(
) ( )
. . . . : ) . ( ( ) . (H1N1)
()
( )
.
.
H5N1
.
( ) ( )
/ . /
/
4
EB128/4
APPENDIX 1
/
" /
/ : "
.
5
EB128/4
Appendix 1
/
................................................................................ .............................................................................. ................................................................................ .......................................................... ...................................... ........................................................ H5N1
................................................................. ...................................................... ........................................................... ..................................................... ................................................................. ................................................ ................................................................. ............................... ....................................................................... ..................................... .............................. . " " " " "
"
/ "
"
"
."
6
EB128/4
Appendix 1
/
.............................. ......................................................... ......................... ............. ........... ........................................ .................................................. ................................................................ ................................................
............................................................. ............................................................ ] ...................................................................... [ ................................................................
......................................................... ............................................... . [ ................................................................... H5N1
]
7
EB128/4
Appendix 1
/
[
]
. .
]
. [. : : ( (
(
)
:
) )
( H5N1
) ( )
(
) ( ) ( ( H5N1 H5
) )
(
)
8
EB128/4
Appendix 1
/
( ( H5N1
) )
(
( ( (
)
) ) )
(
) ( H5N1
)
(
) ( )
( [ ( ) * [ ] ( ](
) ) )] *]
[
[ [. [ ]/[ ](
] )]
[. http://www.who.int/csr/ihr/ar/.
]
9
EB128/4
Appendix 1
/
[ ." " . (
] )
( H5N1
) " ( )
( (
) ) ( ( ) )
(
) ( )
(
) ( )
( ( ) (
) )
WHO/CDS/EPR/GIP/2006.1; http://www.who.int/csr/resources/publications/influenza/CDS_EPR_GIP_2006_1.pdf.
10
EB128/4
Appendix 1
/
:[ H5N1
] ( )
.
[
]
( )
H5N1
(
).
(
).
11
EB128/4
Appendix 1
/
"
"
H5N1"
) (."
(
).
) /
"
( / H5N1 ] [ /
"
( H5N1
). ["
"
] " "
.
(
). "
"
( " /
).
.
" H5N1
(
). "
"
.
12
EB128/4
Appendix 1
/
.
(
) " H5N1
( "
)
( ( / / . ) ] [[ [ "
). " ] " ] "
[
]/
(
). " "
.
). " "
( ( ). / " "
(
(
).
)
" [ ] .
"
(
).
13
EB128/4
Appendix 1
/
" /
"
(
).
H5N1
"
" ] " "
( .
).
[
( / [
). ] " "
( [ .
). "
]
" . H5
(
) "
"H5 H5
(
). [" "] .
).
[ H5
]
(
.
(
"
).
"
14
EB128/4
Appendix 1
/
(
). ( ). ( [ ] ] ] [ "
" H5N1
" " "
" " .
).
" "
.[ " ]"
] /[
" " "
( [
).
(
). " H5N1
[
] "
( ( "
). ).
" [ ] H5N1
" ]"
( (
). ).
"
"
15
EB128/4
Appendix 1
/
H5N1
(
H5N1
) :[
]
(
) H5
( ) H5
( )]
:[ [.
]
( )] : ] [ ] [ / / H5
() ( ) ( )
[.
( )
16
EB128/4
Appendix 1
/
.
H5
( ) . ( ) ( ) ( ) ( )
.
( ) ]
[
H5
] /[ .[ ( )
]
H5N1
( ( ( ). )
) :H5 ( ) ( )
H5N1
/
(
).
H5
H5N1
(
) .[
]
17
EB128/4
Appendix 1
/
(
) ( ):
H5N1
(
).
[
]
(
).
H5
(
).
( [
) .[ ]
]
.
.
.
(
).
"
"
."
/
"
18
EB128/4
Appendix 1
/
[ ] [ [
]
[
/ [
] ] .[
[
[
]
] ] ] .[ ]
[[
] [[ H5
] [[. [
]
]
]
] [[.
]]
] ( ) [.
[
]]
"
"
"
"
.
19
EB128/4
Appendix 1
/
. :
(
)
( .
)
( ) ( )
( ) H5N1
(
)
. ( )
( .
). ( )
[
]
(
).
20
EB128/4
Appendix 1
/
(
). ( ).
H5
(
).
/ H5
( ( ) ( )
): ( )
) ( )
( ) ( )
(
).
(
H5
( /
). [ ]
21
EB128/4
Appendix 1
/
(
).
).
H5N1
(
(
).
H5N1
( ( ( ( .
): ) ) ) ( ) ( ) ( ) ( ) H5
(
)
(
).
22
EB128/4
Appendix 1
/
H5N1
( ( /
).
)
).
H5N1
(
H5N1
(
).
.
(
)
H5N1
(
).
( )
):
H5N1
.
( )
(
23
EB128/4
Appendix 1
/
( )
(
).
H5N1
(
) .(
)
H5N1
(
). ( )
H5N1
(
).
(
).
(
).
:
(
)
H5N1
/
H5N1
)
(
) .(
24
EB128/4
Appendix 1
/
(
)
.
(
)
H5N1
. .
(
).
/
(
).
(
).
(
).
25
EB128/4
Appendix 1
/
(
).
.
(
).
(
)
(
)
(
): ( ( ( ) ). ( ) ( ) /
)
( ) ( ) ( )
26
EB128/4
Appendix 1
/
( "
). / " () ( )
( ( ).
):
. () " "
(
). ( )
.
(
).
(
).
[
]
(
).
( ( ).
).
27
EB128/4
Appendix 1
/
. [ [ ( H5N1
: ] ] [ ) ] ( ) ( ) ( ) ( )
(
).
( )
(
).
[
]
.
H5
]
H5
( [[ . [ H5
). [
[ ] ]
] ]
(
.
).
28
EB128/4
Appendix 1
/
.
(
).
29
EB128/4
Appendix 1
/
. . . (" ")
("
"
)
." . . . . " "
"
. .
/ /
30
EB128/4
Appendix 1
/
.
.
.("
") .
. . . .
.
31
EB128/4
Appendix 1
/
("
"
)
H5N1
)
((
)
H5N1
((
)
)
]
: H5N1
[ ( )] ( )
H5N1
) [.
(
]
[ 32
EB128/4
Appendix 1
/
[ .("
")
("
")
]
:
( ( :
) (" ) .( "
" "
)( )(
): ):
]
[.
[
]
[.[
]
]
(
).
[.
]
.(
)[
]
. .
33
EB128/4
Appendix 1
/
[ : .
]
.
(
).
[.
]
[ : . ] [. [ ] [
]
][
]
] /[
(
). [ . ]
. ). ." " /
(
34
EB128/4
Appendix 1
/
: ( [...
[ ] ). ]
[ ]/ : [ ] . [. ] . ]
. [
.
[.
]
. :
35
EB128/4
Appendix 1
/
: : : . [ . ] . . .
() ( ) ( )
[
]
. .( . . [ ] )
/ . "
/[ ] " " "
36
EB128/4
Appendix 1
/
(
).
[.
]. ....................................
(
)
.................................... ................................
[.
]. ....................................
(
)
.................................... ...............................
. ....................................
( .................................... ................................
)
. ....................................
( .................................... ...............................
)
37
EB128/4
Appendix 1
/
( . [ [ )] [ . ][ [( ] ] ]
)
( . ( " " [ [. .
) . ) ]. ]
( .
)
. . "
"
" / " .
38
EB128/4
Appendix 1
/
[
:
]
.
/
39
EB128/4
Appendix 1
/
(
/
)
. . .(" " H5N1
.
/
)
"
. H5
.
.
[ ]
. : ] H5N1
. () [ ( )
40
EB128/4
Appendix 1
/
( ) . . . . . ()
.
. . .
. .
.
.
.
. .
41
EB128/4
Appendix 1
/
.
.
42
EB128/4
Appendix 1
/
: H5
. .
[ [ .[ . ]
]
] .
.
. . . .
. [ . . [ ]
] .[
:
]
[
]
43
EB128/4
Appendix 1
/
[
] H5N1
[ .
.
]
[ [ [
] ] ]
. . . [ [ [ . . [ [ . [ [[ ] [ ] ] ]] [. [ ] ] ] ] ] ] ]
[.
44
EB128/4
Appendix 1
/
:
: ( / ( ( ) ( . [ ) ] )
)
( /
) ( )
(
)
http://www.who.int/csr/disease/influenza/centres/en/index.html.
45
EB128/4
Appendix 1
/
).
/ (
.
(
)
(
) ( )
(
) ( [ .(
) ] )
: A(H5)
)
(
(
)
H5 A(H5)
(
)
46
EB128/4
Appendix 1
/
( )
)
/
(
H5N1
( ( ) H5N1
) )
( H5N1
( H5N1
)
(
) [
] :
( ) ) A
)
( ) ( ) ( ( )
47
EB128/4
Appendix 1
/
( . . )
)
(
( A(H5N1)
. ) / ( / ] [.
: / ( ) /
)
/ .(
.
(
)
.http://www.icmje.org/
48
EB128/4
Appendix 1
/
: H5
. .
[ [ .[ ]
]
] .
. .
H5N1 H5N1
.
.
H5
. [ ] .[
[
]
: [
] ] H5N1
[
]
[
.
]
[
]
49
EB128/4
Appendix 1
/
.
[ [ . . [ [ [ . . [ [ . [ [[
] ]
] ] ]
.
] ]
] ]] [. ] [
]
]
[
]
[.
. .
.
50
EB128/4
Appendix 1
/
: ( ( ( )[ / ( .( ) [ ] ) ) ] )
: )
(
H5N1
[ [ / ] ] / H5
] [ )
( ( (
) ( ) )
51
EB128/4
Appendix 1
/
)
.(
: [ ]
.
H5N1
52
EB128/4
Appendix 1
/
H5
: H5
. . .
[ [ .[ ]
]
]
.
. .H5 H5
[
]
.H5N1 A(H5)
]
.
[
.
[
] .[
: [
] ] H5N1
[
]
[ .
.
]
[ [
] ]
53
EB128/4
Appendix 1
/
[ . . . [ [ [ . . [ [ . [ [[ ] [ ]
]
] ] ]
] ]
] ]] [. [
]
]
[.
.
H5
: ( )
54
EB128/4
Appendix 1
/
H5
( ( ) / )[
) ]
A(H5)
(
( )
)
.(
: ( )
)
A(H5)
( A(H5)
(
) /
(
)[
]
A(H5)
(
)
H5 A(H5)
http://www.who.int/csr/disease/avian_influenza/H5AcceptanceCriteria_16Oct07.pdf
55
EB128/4
Appendix 1
/
A(H5)
( / .(
) )
/
: / ( ) /
)
/ .(
.http://www.icmje.org/
56
EB128/4
Appendix 1
/
: H5
.
[ [ .
] ]
. .
.[
]
.
. .
:
. .
.
. [ ] .[
.
:
]
[
]
57
EB128/4
Appendix 1
/
[
] H5N1
[ .
.
]
[ [ [
] ] ]
. . . [ [ [ . . [ [ . [ [[ ] [ ] ] ]] [. [ ] ] ] ] ] ] ]
[.
:
58
EB128/4
Appendix 1
/
: ( H5N1
) ( )
H5N1
(
)
(
H5N1
) ( ) ]
.(
)[
: [ H5N1
(
]
)
H5N1
( [ H5N1
) ]
(
).
(
)
H5N1
H5N1
59
EB128/4
Appendix 1
/
[
]
(
)
[
H5N1
(
]
)
H5N1
.(
)
: / ( ) /
)
/ .(
.http://www.icmje.org/
60
EB128/4
Appendix 1
/
H5N1 [ ] . : [ . ] [ [ [ ] [ . [ [ . [ . . [ [ ] ] ] . ] ] ] ] ] H5N1 H5
[
]
.
61
EB128/4
Appendix 1
/
. [ [[ [ [. ]] [ . [ ] ] ] ] ]
62
EB128/4
APPENDIX 2
/
/ " . /
:
"
63
EB128/4
Appendix 2
/
White Paper 1
(
) .("
")
("
")
:
.
(
):
• ) H5
)] ( [(" " )
(
(
). )
• )] ( [(" "
H5
)(
(
) ."
"
/
[
][
]]
."
"
64
EB128/4
Appendix 2
/
("
"
)
[ .
] . : " " . . " " [.
:
(
). ( : [ [. " " : "
) .
]/
]
:
."
1) Laboratory biorisk management for laboratories handling pandemic influenza A (H1N1) 2009 virus; 2) Safe transport of pandemic influenza A (H1N1) 2009 virus cultures, isolates and patient specimens as Biological Substance, Category B; 3) Guidance to Influenza Laboratories Diagnosing Swine Influenza A/H1N1 Infections of current concern.
65
EB128/4
Appendix 2
/
[.
]
. [.
]
[
]
( [
). ][ ][. ] ]
" [.
"
(
) :
]
.
[
(
) . .
:
."
" " :
"
1) Laboratory biorisk management for laboratories handling pandemic influenza A (H1N1) 2009 virus; 2) Safe transport of pandemic influenza A (H1N1) 2009 virus cultures, isolates and patient specimens as Biological Substance, Category B; 3) Guidance to Influenza Laboratories Diagnosing Swine Influenza A/H1N1 Infections of current concern.
66
EB128/4
Appendix 2
/
(
)
:
]
[. [ ]/ ]
[.
[.
]
] . [.
[
]
67
EB128/4
Appendix 2
/
[. . .
] ]
[[ .
] /[.
]
. " ][ " ]
[.
( / [.
).
/ ]
]
[.
[ ] . [
]/ ]
.
68
EB128/4
Appendix 2
/
[ .
] . [.
. : : : : () ( ) ( )
]
.
. [.
[ .
. ]
. ] . [
]
.
69
EB128/4
Appendix 2
/
. :
.
" " .
.(
)
.
" [.
"
[
] [. . ]
] /[. "
] "
.
.[
/ . " "
] " "
70
EB128/4
Appendix 2
/
.
[.
/ . " " [. . " "
]
. ....................................
( .................................... ............................... ( ( .................................... ............................... ( ) H5
)
) H5
...................................... )
. ....................................
......................................
71
EB128/4
Appendix 2
/
. ... .
. [.
□
72
EB128/4
Appendix 2
/
White Paper 1
("
")
." . . "
"
" "
"
: . : . . ( )
• • •
. .
• .
73
EB128/4
Appendix 2
/
. . .
• • •
.(
)
.
. . . .
"
"
.
. . . . . . . " "
. .
.
74
EB128/4
Appendix 2
/
White Paper 2
.("
")
("
")
:
:
.
• . ." "
•
/ . (" " )
: .
75
EB128/4
Appendix 2
/
. . ." " .
. .
.
. . . / . / . /
."
" "
"
76
EB128/4
Appendix 2
/
."
"
"
"
. : : : : () ( ) ( )
. . ] . .
[ .
. .( . )
77
EB128/4
Appendix 2
/
.
"
"
/ . " . " . " "
78
EB128/4
Appendix 2
/
White Paper 3
...... .(" ") (" " " ")
:
.
:
• )( ) "
.("
. ." "
•
)(
.("
"
)
79
EB128/4
Appendix 2
/
/ . (" " )
.
:
" " . .
: . . . ." . "
."
" "
"
80
EB128/4
Appendix 2
/
:
.
. [ ]
. / / .
81
EB128/4
Appendix 2
/
/ .
. .
."
"
"
"
.
) . : : : :
(
() ( ) ( )
. . ] .
[ .
82
EB128/4
Appendix 2
/
. .
.
. .( . )
.
"
"
/ . " . " . " "
.
. ....................................
( .................................... ............................... 83
)
EB128/4
Appendix 2
/
. ....................................
( ................................... ...............................
)
. ... .
. .
□
84
EB128/4
Appendix 2
/
White Paper 4
: ( [ : / / [ ] ] )
. : : × ‚× / : () ( )
.
85
EB128/4
Appendix 2
/
/
." ) (
"
GAP
/
=
=
=
) . . .
.
(
86