Recent WHO publications

Recent WHO publications/Publications recentes OMS Readers living in developing countries receive a 30% reduction on the prices indicated in Swiss francs. Les lecteurs r6sidantdans les pays en developpementb6n6ficientd'un rabais de 30% surles tarifs indiques en francs suisses. Cancer International classification of diseases for oncology (ICD-O) Second edition C. Percy, V. Van Holten, & C. Muir, ed. Geneva, 1990, xlv+144 pages ISBN 92 4 154414 7 Price: Sw.fr. 30.-/US$ 24.- The second edition of this standard international coding tool for cancer registration represents an extension of Chapter II (Neoplasms) of the Tenth Revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10). The new edition was developed in collaboration with the US National Cancer Institute (NCI) and the WHO International Agency for Research on Cancer (IARC). The classification, which has been finalized following extensive field testing throughout the world, permits the coding of all neoplasms as malignant, benign, in situ, of uncertain behaviour, or metastatic. As in the previous edition, a separate code for histologic grading and differentiation has been included. The following features are new: -adoption of the ICD-10 classification for tumour topography with its alphanumeric coding system; -inclusion of several new histologic types in the morphology section; -complete remodelling of the section on non- Hodgkin's lymphoma; and -expansion of the sixth-digit code for histologic grading and differentiation in order to identify T- and B-cell involvement for lymphomas and leukaemias. ICD-O, which comes into force before ICD- 10, can be used for both topographic sites and histologic types of neoplasms by those who wish to code greater detail about a neoplasm than is provided for in the neoplasms chapter of ICD-10. Since the great majority of users are from tumour registries, this edition features specific instructions for tumour reg- istrars as well as for pathologists. Chemical toxicology, carcinogenicity Pesticide application equipment for vector control Twelfth report of the WHO Expert Committee on Vector Biology and Control Geneva, 1990, 58 pages (WHO Technical Report Series, No. 791). ISBN 92 4 120791 4 Price: Sw.fr. 8.-/US$ 6.40 Addressed to manufacturers of pesticide application equipment used in vector control operations as well as to specialists in vector control, this book concen- trates on recent trends that are redefining the ap- proach to effective vector control. These include intense concern about the environmental impact of chemicals, growing appreciation for the necessity of an integrated approach to control, and a correspond- ing move towards such non-chemical measures as environmental management and the use of biological agents. Noting the continuing need for pesticides, particularly in the emergency response to epidemics, the book places particular emphasis on the demand for equipment that is both suitable for use by com- munities and capable of delivering accurate and judi- cious quantities of pesticides. The book also addresses safety issues and dis- cusses the crucial roles of information dissemination, training, and research. In a series of annexes are given a table showing modes for transporting the main species of larvivorous fish, suggested curricula for training operators, supervisors, and managers, and a detailed list of amendments to WHO specifications for pesticide application equipment. Bulletin of the World Health Organization, 68 (6): 807-813 (1990) 807 Recent WHO publications Formaldehydea Geneva, 1989, 219 pages (Environmental Health Criteria, No. 89). ISBN 92 4 154289 6 Price: Sw.fr. 22.-/US$ 17.60 Formaldehyde, a flammable, colourless and readily polymerized gas present in the environment from both natural and man-made sources, is produced indus- trially in large quantities for a wide range of ap- plications. These include the production of glue or coatings for particle boards and plywood, the manu- facturing of sterilizing and disinfecting agents, medi- cines, cosmetics, and a number of consumer goods. Other major man-made sources are automobile and aircraft exhaust emissions, tobacco smoke, natural gas, fossil fuels, waste incineration, and oil refineries. The book makes a clear distinction between outdoor and occupational exposures, and exposures arising from the emission of formaldehyde into indoor air environ- ments. Particular attention is given to hospitals and scientific facilities, where formaldehyde is used as a sterilizing and preserving agent, and living spaces, such as schools, kindergartens, and mobile homes or apart- ments, where uncontrolled emissions of formaldehyde from tobacco smoking, building materials, and furni- ture may pose a particular health hazard. Concern about the toxicological effects of formal- dehyde is addressed in a review of data from experi- mental animals and in vitro test systems. The section on health effects in man draws upon clinical and epidemiological studies to evaluate sensory, toxic, respiratory, dermal, genotoxic effects and effects on reproduction. The evaluation cites evidence of a possible cancer risk for humans from exposure to formaldehyde, but concludes that the carcinogenic potential is not high, that only nasal or nasopharyn- geal tumours are likely to be causally related to formaldehyde exposure, and that formaldehyde is not teratogenic. Permethrin5 Geneva, 1990, 125 pages (Environmental Health Criteria, No. 94). ISBN 9241542942 Price: Sw.fr. 15.-/US$ 12.- This book evaluates the design and findings of over 250 studies concerned with the effects on human health a Published by WHO under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and WHO (International Programme on Chemical Safety-IPCS). and the environment posed by permethrin, a photo- stable synthetic pyrethroid insecticide marketed since 1977. Because of its strong repellent properties and effectiveness as a stomach and contact insecticide, permethrin is widely used in the protection of several agricultural crops, in the control of insects in house- holds and on cattle, in aerial application for forest pest control, as a fog in mushroom houses, and as a wood preservative. Public health applications include the disinsection of aircraft, treatment of mosquito nets, and human lice control. One section describes the large number of studies investigating residues in fruits, vegetables, dairy milk, and grains. Other sections review findings on the environmental behaviour of permethrin, its metabolic pathway,s in mammals, and its effects on non-target organisms. The most extensive section presents the findings of experimental studies conducted to assess toxicity, primary irritation, sensitization, long-term toxicity, carcinogenicity, mutagenicity, teratogenicity, neurotoxicity, and behavioural effects. On the basis of this review, the book concludes that most toxic effects are transitory, that the likelihood of carcino- genic effects in humans is extremely low or non- existent, and that permethrin, when used as recom- mended, is not likely to present a hazard to the general public, exposed workers, or the environment.b Fenvaleratea Geneva, 1990, 121 pages (Environmental Health Criteria, No. 95). ISBN 92 4 154295 0 Price: Sw.fr. 15.-/US$ 12.- A synthetic pyrethroid insecticide widely used for crop protection since 1976, fenvalerate is also used in homes and gardens and for the control of insect infestation in cattle. The opening section of the book describes the properties of fenvalerate and identifies appropriate methods for environmental sampling and the analysis of residues. A brief discussion of sources of human exposure, concentrating on studies of dietary residues, concludes that residues in crops grown by good agricultural practice are generally low. Other sections outline metabolic pathways and summarize studies of effects on aquatic and terrestrial organisms, including investigations of uptake, loss, and bioaccumulation. The remaining chapters evaluate the effects on health, based on the results of animal experimentation, in vitro tests, case studies of accidental exposure, and bA summary, evaluation, conclusions, and recommendations in French are included in the book. 808 WHO Bulletin OMS Vol. 68. 1990. Recent WHO publications clinical investigations. The book concludes that expo- sure of the general population is very low, that the effects of occupational exposure are transitory, and that risks to the environment and human health are unlikely when fenvalerate is applied as recommended.b d-Phenothrina Geneva, 1990, 64 pages (Environmental Health Criteria, No. 96). ISBN 9241542969 Price: Sw.fr. 10.-/US$ 8.- This book evaluates the risks to human health and the environment posed by d-phenothrin, a synthetic pyrethroid insecticide used primarily for the house- hold control of noxious insects, including head lice, and the post-harvest treatment of stored grain. Fol- lowing information on the properties and methods of sampling and analysis, the available data on world- wide industrial production and use are reviewed. One section on investigations of photodegradation and transport concludes that photodegradation under outdoor conditions is rapid, but that d-phenothrin remains virtually intact for up to 12 months on grains stored in the dark. The most extensive chapter evalu- ates toxicological data from studies in experimental animals and in in vitro test systems, concentrating on investigations performed to assess embryotoxicity, teratogenicity, and neurotoxicity. On the basis of these evaluations, the book concludes that d-phenothrin, when used as recommended, is not likely to pose a hazard to either human health or the environment.b Methylmercurya Geneva, 1990, 144 pages (Environmental Health Criteria, No. 101). ISBN 92 4 157101 2 Price: Sw.fr. 16.-/US$ 12.80 This book evaluates the risks to adult and fetal health posed by exposure to compounds of monomethylmer- cury and makes a special effort to clarify the ways in which this highly mobile metal enters the food chain and to define the levels that constitute a risk to human health. Close to 400 recent investigations, including numerous clinical studies following outbreaks of poi- soning, are critically assessed. The conclusions con- cerning levels of exposure and the associated risks to health are as follows: the general public is determined to be at low risk of methylmercury poisoning, but populations consuming high quantities of fish may attain a blood methylmercury level associated with a low risk of neurological damage to adults. In view of the particular sensitivity of the fetus to methylmercury, exposure during pregnancy is judged to carry a high risk of neurological disorder in the offspring. Principles for the toxicological assessment of pesticide residues in fooda Geneva, 1990, 117 pages (Environmental Health Criteria, No. 104). ISBN 9241571047 Price: Sw.fr. 15.-/US$ 12.- This book, which was prepared by a 30-member task group in collaboration with a large number of experts, responds to requests for an explanation of the prin- ciples, and their scientific basis, developed over the years by the Joint FAO/WHO Meeting on Pesticide Residues (JMPR). By documenting a progression of refinements in methodology and data requirements, it also provides a view of both the strict criteria used in JMPR assessments and the responsiveness of these criteria to advances in scientific knowledge. The most extensive chapter provides a step-by-step guide through the battery of test methodologies currently used in the safety assessment of pesticide residues. Both classical experiments and very new tests in the fields of immunotoxicity and behavioural toxicity are critically reviewed in terms of their capacity to con- tribute to the safety assessment. Other chapters ex- plain principles governing the extrapolation of animal data to humans, the allocation of an acceptable daily intake, the evaluation of mixtures, and the re-evalu- ation of pesticides. The book concludes with a dis- cussion of principles for dealing with microbial pest- control agents and bioengineered organisms, followed by advice on the special methodological problems posed by the organophosphates, bipyridilium com- pounds, and goitrogenic carcinogens. Some flame retardants and textile chemicals, and exposures in the textile manufacturing industry Lyon, International Agency for Research on Cancer, 1990, 345 pages (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 48). ISBN 92 832 1248 7 Price: Sw.fr. 65.-/US$ 52.- Separate monographs are presented in this book for six flame retardants and other textile chemicals, such as nitrilotriacetic acid and its salts. Although nitrilo- triacetic acid and its salts are most widely used as the basis for laundry detergents, evaluations of these WHO Bulletin OMS. Vol. 68. 1990. 809 Recent WHO publications chemicals were included in view of their use in the textile industry to remove interfering metal ions from textile processing solutions. The most extensive mono- graph evaluates the carcinogenic potential of occupa- tional exposures in the textile manufacturing industry. A brief history and description of the industry is followed by a review of data on occupational expo- sures to organic dusts, dyes and their components, finishing agents and their components, and other agents, including bacteria, endotoxins and various solvents. Evaluations of carcinogenic risk concentrate on epidemiological evidence of carcinogenicity at the oral and pharyngeal, oesophagus and stomach, nasal cavity, larynx, lung and bladder sites. In view of the strength of the findings of bladder cancer among dyers and among weavers and of cancer of the nasal cavity among weavers and other textile workers, the mono- graph concludes that working in the textile manufac- turing industry entails exposures that are possibly carcinogenic to humans. Cross Index of synonyms and trade names In volumes 1 to 46 In collaboration with the International Programme on Chemical Safety (WHO-ILO-UNEP) Lyon, International Agency for Research on Cancer, 1989, v+346 pages (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Supplement 8). ISBN 92 832 1417 X Price: Sw.fr. 60.-/US$ 48.- In the first 46 volumes of the IARC Monographs, 660 individual chemicals, groups of chemicals or complex mixtures have been evaluated. In the first section of each Monograph a number of synonyms and trade names have been included for each chemical or complex mixture and thus, progressively it has become more and more difficult for the reader to determine whether a chemical or a complex mixture has been evaluated by an IARC working group. Collaboration was sought with the WHO-ILO-UNEP International Programme on Chemical Safety (IPCS) to create a cross index ofsynonyms and trade names which would provide an easy reference source for the chemicals considered in the first 36 volumes of the Monographs. The resulting cross indexes were published as Supple- ment 5. The present cross index has been updated to cover volumes 1 to 46 of the Monographs. Continued updating of this data base is envisaged and periodic supplements are planned. Health of the elderly Health, lifestyles and services for the elderly edited by W.E. Waters, E. Heikkinen, & A.S. Dontas Copenhagen, WHO Regional Office for Europe, 1989, xx+222 pages (Public Health in Europe, No. 29). ISBN 92 890 1165 3 Price: Sw.fr. 20.-/US$ 16.- In recognition of the increased aging of European populations and the need for comparative baseline data to help in future health planning, WHO com- mitted resources in 1979 to an international study carried out by 15 centres in 11 countries. The first report on that studyC provided findings on a sample of respondents aged 60-90 years and covered their health and functional ability, living conditions, way of life and use of services. These findings were pre- liminary and purely descriptive, and much more information was generated by the study than could have been included in the first report. The present analysis permits a deeper insight into health and functioning in old age, into the living conditions of the elderly, and into the use of services by different groups. The data presented should con- tribute to a better understanding of the health and social problems of elderly people and their needs in the last decade of this century. Pharmaceuticals, biologicals International reporting of adverse drug reactions Final report of CIOMS Working Group Geneva, CIOMS, 1990, 66 pages ISBN 92 9036 042 9 Price: Sw.fr. 10.-/US$ 8.- This book sets out a carefully developed and tested procedure for the standardized reporting, by manu- facturers to regulators, ofpost-marketing adverse drug reactions occurring in foreign markets. The procedure, which is now published in its final form, is the culmination of a three-year project initiated by the Council for International Organizations of Medical c Helkkinen, E. et al. The elderly in eleven countries. A socio- medical survey. Copenhagen, WHO Regional Office for Europe, 1983 (Public Health in Europe, No. 21), xx+231 pages, ISBN 92 890 1157 2. 810 WHO Bulletin OMS. Vol. 68. 1990. Recent WHO publications/Publicatlons r6centes OMS Sciences (CIOMS) in collaboration with WHO.d The book opens with a discussion of factors that have created an urgent need to coordinate and stand- ardize the procedures by which drug manufacturers communicate adverse drug reactions, occurring out- side the domestic market, to regulatory bodies. The main part of the book presents and explains the CIOMS procedure for the international reporting of adverse drug reactions. The procedure, which was worked out and agreed upon by representatives of six regulatory authorities and seven manufacturers em- ploys a uniform set of definitions and procedures, a fixed time-frame for submission of the report, and a reporting form with standardized elements and for- mat. The second half of the book presents evaluations of the scheme prepared by each of the participating regulatory authorities and manufacturers. At present, the CIOMS scheme has been adopted for use in the United Kingdom, the USA, the Federal Republic of Germany, and Italy. The French regulatory author- ities are moving towards the adoption of a similar approach. d The reports of the previous working group meetings were reviewed in the Bulletin of the World Health Organization, 65 (4): 567 (1987) and 66 (3): 417-418 (1988). CIOMS publications may be obtained directly from CIOMS, c/o World Health Organization, 1211 Geneva 27, Switzerland. They are also distributed by WHO's Distribution and Sales service, at the above address, or by the WHO sales agents. A list of these agents may be obtained by writing to the above address. Substance abuse Drug abusers in prisons: managing their health problems Report on a WHO Meeting Copenhagen, WHO Regional Office for Europe, 1990, vi+52 pages (WHO Regional Publications, European Series, No. 27). ISBN 9289011181 Price: Sw.fr. 10.-/US$ 8.- The proportion of drug abusers in prisons has grown enormously in recent decades, putting a great strain on the health services available to prisoners. This publication looks at the methods used to identify drug abusers on admission to prison and the health care measures taken to treat drug dependence. It looks closely at the special nature of drug treatment in prison: both the ethics of treating people who are incarcerated against their will and the likely effect of their lack of motivation on the outcome. It also looks at health problems related to drug abuse, such as AIDS and suicide. This in-depth review of the special problems of drug abusers in prisons should be read by those in the public health and criminal justice sectors who are responsible for the health and welfare of the prison population, as well as by researchers concerned with methods of treating drug dependence. Maladies transmissibles Guide pour la planification des activites de promotion de la sante pour la lutte contre le SIDA Geneve, 1990, iv+79 pages (Serie OMS SIDA 5). ISBN 92 4 221005 6 Prix: Fr.s. 14.- Cet ouvrage est un guide detaille sur la maniere d'utiliser efficacement l'information et l'education pour convaincre le public de modifier ses comporte- ments afin d'endiguer la propagation du SIDA. Des- tine aux responsables de la planification et de la gestion d'une campagne de promotion de la sante pour la lutte contre le SIDA, des lignes directrices y sont donnees concernant l'utilisation de certaines methodes et techniques d'education dont l'efficacite a et aver6e dans d'autres grandes campagnes de promotion de la sante qui avaient pour but de modifier le comporte- ment des individus et des groupes. Les lecons et les exemples tires des diverses campagnes de lutte contre le SIDA, qui sont livres tout au long de cet ouvrage doivent aider les planificateurs 'a prevoir les problemes, a reconnaItre les mesures qui ont le plus de chances d'aboutir et a' se premunir contre les ecueils courants. Le livre s'acheve sur des conseils sur la facon d'effectuer le test prealable d'un message propose pour determiner si le public vise le comprendra, l'appreciera et le trouvera convaincant. Guide concernant le SIDA et les premiers secours sur le lieu de travail Publie en collaboration avec le Bureau international du Travail et la Ligue des Societes de la Croix-Rouge et du Croissant-Rouge WHO Bulletin OMS. Vol. 68. 1990. 811 Publications r6centes OMS Geneve, iii + 12 pages (Serie OMS SIDA 7). ISBN 92 4 221007 2 Prix: Fr.s. 4.- Ce guide contient des informations generales sur la transmission du virus de l'immunodeficience humaine (VIH) et des indications specifiques sur les risques associes a l'administration des premiers secours a un travailleur blesse. Il traite successivement de la re- animation par le bouche-a-bouche, des mesures 'a prendre en cas de saignements, du nettoyage des souillures de sang, et des prescriptions a appliquer immediatement quand un secouriste a ete en contact avec du sang. Le guide rassure aussi les secouristes en leur rappelant que le risque de contracter une infection a VIH lors du bouche-a-bouche ou du traitement d'une hemorragie est tres faible et ne doit pas servir de pretexte pour ne pas donner des soins qui peuvent etre vitaux. Le guide se termine par une declaration de consensus sur le SIDA et le lieu de travail, avec des conseils sur l'elaboration des politiques de l'emploi. Preparations pharmaceutiques, produits biologiques Comite OMS d'Experts des Specifications relatives aux Preparations pharmaceutiques Trente et unieme rapport Geneve, 1990, 85 pages (OMS, Serie de Rapports techniques, No 790). ISBN 92 4 220790 X Prix: Fr.s. 9.- Ce rapport publie les recommandations et conclusions d'un comite d'experts dont les travaux repondaient a la necessite d'aider les laboratoires de contr6le des medicaments et les organismes de reglementation pharmaceutique a proceder au controle de la qualite des preparations pharmaceutiques. Il se compose de deux grandes parties. Dans la premiere, le comite appelle brievement l'attention sur plusieurs evalua- tions techniques et problemes pratiques qui interessent le fonctionnement des laboratoires de contr6le de la qualite. Parmi les questions examinees figurent l'assurance de la qualite des produits obtenus par genie genetique, l'incapacite, a partir des donnees de stabilite rassemblees en climat tempere, de prevoir la duree de conservation en climat tropical, et enfin les problemes sp6ciaux que posent les preparations pharmaceutiques faussement etiquetees, falsifiees, contrefaites ou ne repondant pas aux normes. La deuxieme partie se compose de six annexes consacrees 'a la stabilite des medicaments, aux methodes d'echantillonnage pour les produits pharmaceutiques fabriques industrielle- ment, aux directives pour la preparation et l'examen des monographies destinees 'a figurer dans la Pharma- copee internationale, 'a la liste des substances chimiques internationales de reference (1988), et au Systeme OMS de Certification de la qualite des produits pharmaceutiques entrant dans le commerce interna- tional. La derniere annexe contient des principes directeurs 'a l'intention des petits organismes natio- naux de reglementation pharmaceutique qui devraient les aider 'a mettre en place un systeme technique et administratif fiable pour l'homologation des produits pharmaceutiques. Sante maternelle et infantile, sante des adolescents Participation communautaire aux programmes de sante maternelle et Infantile/planification familiale Analyse sur la base d'etudes de cas S.B. Rifkin Geneve, 1990, x+44 pages ISBN 92 4 256135 5 Prix: Fr.s. 9.50 Destine aux planificateurs de la sante, cet ouvrage traite de problemes de gestion et de facteurs comporte- mentaux dont il faut tenir compte pour planifier les programmes de sante fondes sur la notion ou les methodes de participation communautaire. Tout au long du livre, l'auteur se refere a de nombreuses etudes de cas pour mettre au point un cadre analytique qui permette de comprendre pourquoi ces programmes ont si souvent des difficultes 'a atteindre leurs objectifs. Le cadre analytique de l'etude est egalement expose, qui decrit des programmes en fonction de leurs objectifs et des methodes appliquees pour les atteindre. On peut distinguer cinq niveaux de participation differents. L'auteur propose deux series de facteurs pour faire le point de l'etat d'avancement d'un pro- gramme et verifier si ses objectifs ont ete atteints: les facteurs descriptifs qui concernent principalement le cadre general, et les facteurs d'action qui concernent l'organisation, la gestion et la mobilisation des res- sources. Considerant que les facteurs descriptifs sont particulierement difficiles 'a modifier, l'auteur s'in- teresse 'a six facteurs d'action pour montrer comment ils peuvent favoriser ou entraver une participation communautaire efficace. WHO Bulletin OMS. Vol. 68 1990.812 Publications r6centes OMS Toxicologie des substances chimiques, carcinogenicite Evaluation de certains additifs alimentaires et contaminants Trente-cinquieme rapport du Comite mixte FAO/OMS d'Experts des Additifs alimentaires Geneve, 1990, 51 pages (OMS, Serie de Rapports techniques, No 789). ISBN 92 4 220789 6 Prix: Fr.s. 6.- Ce rapport, qui contient les conclusions d'un comite d'experts charge de faire l'evaluation toxicologique systematique de certains additifs alimentaires et con- taminants dans les aliments, presente egalement des normes d'identite et de purete pour certains additifs alimentaires afin de verifier que les produits soumis a des epreuves toxicologiques sont bien definis et cor- respondent aux produits se trouvant dans le com- merce. Sont exposees a l'intention du lecteur, plusieurs considerations generales dont s'est inspire le comite pour reviser les normes concernant certaines prepara- tions enzymatiques, des substances d'origine naturelle et des residus de solvants. Dans la partie principale du rapport sont resumees les evaluations des donnees toxicologiques sur certains emulsifiants, preparations enzymatiques, aromatisants, colorants alimentaires, epaississants, autres additifs et contaminants-la patuline et les polychlorobiphenyles (PCB). Le rapport se termine par un tableau ou' sont resumees les doses journalieres admissibles et enumeres les changements de normes pour les substances examinees par le comite. Une derniere annexe donne la liste des nouvelles etudes toxicologiques souhaitables ou necessaires. Materiel d'application des pesticides pour la lutte antivectorielle Douzieme rapport du Comite OMS d'Experts de la Biologie des Vecteurs et de la Lutte antivectorielle Geneve, 1990, 55 pages (OMS, Serie de Rapports techniques, No 791). ISBN 92 4 220791 8 Prix: Fr.s. 8.- Destine aux fabricants du materiel d'application des pesticides utilises dans les operations de lutte antivec- torielle aussi bien qu'aux spsecialistes de la lutte antivectorielle, cet ouvrage passe en revue des evenements recents qui ont conduit a redefinir l'approche d'une lutte antivectorielle efficace. Parmi eux figurent l'intense preoccupation que suscitent les effets des substances chimiques sur l'environnement, une prise de conscience croissante de la necessite d'une lutte integree et une evolution correspondante vers des mesures non chimiques telles que l'amenagement de 1'environnement et l'utilisation d'agents bio- logiques. Notant que le recours aux pesticides est encore necessaire, notamment dans les situations d'urgence creees par les epidemies, l'ouvrage insiste sur le besoin en materiels pouvant etre utilises par les communautes et capables de pulveriser des quantites de pesticides precises et judicieuses. Le rapport traite egalement des problemes de securite ainsi que de la diffusion de l'information, de la formation et de la recherche dont les roles sont essentiels. Dans une serie d'annexes, on trouve notam- ment les modalites de transport des principales especes de poissons larvivores, des propositions de pro- grammes pour la formation des operateurs, des sur- veillants et des administrateurs de projets, ainsi qu'une liste detaillee d'amendements des normes OMS pour le materiel de lutte contre les vecteurs. Les services de controle de la securite des denrees alimentaires Deuxieme edition Copenhague, Bureau regional de l'Europe, 1989, x+217 pages (La Sante publique en Europe, No. 28). ISBN 92 890 2164 0 Prix: Fr.s. 18.- La presente publication constitue une remise 'a jour d'une etude anterieure sur les services de controle de la securite des denrees alimentaires dans la Region europeenne de l'OMS,' et dont il ressortait que les services nationaux charges de ce contr6le se sont developpes dans des conditions differentes, qu'il s'agisse de la forme de gouvernement, de l'histoire, de la tradition et de la philosophie politique. La seconde enquete montre que les problemes subsistent et cette deuxieme edition adopte la meme presentation que la premiere. Les analyses par pays font suite 'a un panorama d'ensemble. Bien evidemment, selon la quantite de renseignements dont on dispose et la complexite du reseau de controle des denrees alimen- taires, certains pays font l'objet d'une description plus longue que d'autres, encore que de nombreuses la- cunes aient et comblees. Chaque "profil" de pays est divise en deux grandes sections: la legislation alimen- taire et l'administration du controle des denrees alimentaires et se termine par une liste d'adresses pertinentes, notamment celle du point de contact codex. "Services de contr61e de la securite des produits alimentaires. Copenhague, OMS, Bureau regional de l'Europe, 1982 (La Sante publique en Europe, No 14), vii+201 pages, ISBN 92 890 2150 0. WHO Bulletin OMS. Vol. 68. 1990. 813