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Weekly Bulletin on Outbreaks and other Emergencies: Week 16: 15-21 April 2017

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WEEKLY BULLETIN ON OUTBREAKS AND OTHER EMERGENCIES Week 16: 15 – 21 April 2017 Data as reported by 17:00 21 April 2017 REGIONAL OFFICE FOR

Africa

WHO Health Emergencies Programme

2 New Events

Ongoing events

40

34 Outbreaks

Humanitarian crises

8

1367 15 283 56 98 0 118 3 Cabo Verde Senegal Burkina Faso Guinea 5,262 19 Sierra Leone Mali 72 17 515 4 Chad 47 0 26,966 731 Central African 25 9 Republic 2 0 Cameroon 32 5 Democratic Republic of Congo South Sudan 1100 6,220 172

1,767 115 Niger Nigeria

Benin 2743 21 Togo 8057 745 12 4 2 1

Ethiopia Kenya 167 0

1 0 Legend Food insecurity Meningitis Rift Valley Fever

90

6 376 26

Sao Tome & Principe 48 17 129 13

Uganda

235 4

Humanitarian crisis Necrotising Fasciitis Measles Typhoid fever post El-Nino drought Crimean-Congo Haemorrhagic Fever Anthrax Influenza like illness (H1N1) Lassa Fever Non WHO African Region WHO Member States with no ongoing events Not applicable

38,511 1419 1556 0

Burundi Tanzania 25,132 390 1 0 2,600,409 1,170

Leishmaniasis Monkeypox Zika Floods/Cyclone Cholera Dengue Fever Cases Deaths Hepatitis E Malaria

Angola

Malawi 18 0 Mozambique 1400 3

336 15

Namibia 4 1

Zimbabwe

Madagascar

N W 2572 10

E S

Grade 3 events

3

Grade 2 events

6

Grade 1 events

2

Ungraded events

31

Health Emergency Information and Risk Assessment

Overview Contents 1 Overview 2 - 3 New events 4 - 8 Ongoing events 9 Summary of major challenges and proposed actions This weekly bulletin focuses on selected public health emergencies occurring in the WHO African region. WHO AFRO is currently monitoring 42 events: three Grade 3, six Grade 2, two Grade 1, and 31 ungraded events. This week, two new events have been reported: monkeypox outbreaks in Sierra Leone and Central African Republic. In addition, two events have been graded: the acute watery diarrhoea/cholera outbreak and the humanitarian crisis in Ethiopia have been elevated to grade 3 emergency while the meningitis outbreak in Nigeria has been graded as level 2 emergency. The bulletin also focuses on key ongoing events in the region, including the grade 3 humanitarian crisis in South Sudan, the grade 2 cholera outbreak in Democratic Republic of Congo and the meningitis outbreak in Niger. For each of these events, a brief description followed by public health measures implemented and an interpretation of the situation is provided. A table is provided at the end of the report with information on all public health events currently being monitored in the region. Major challenges to be addressed include: • Timely laboratory confirmation of disease outbreaks in order to implement appropriate control measures. • The prompt availability of sufficient doses of vaccines in order to implement effective reactive vaccination campaigns.

10-11 All events currently being monitored

Health Emergency Information and Risk Assessment

1

New events Monkeypox Event description

Sierra Leone

1 Cases

0 Deaths

0% CFR

A single case of monkeypox has been confirmed in Pujehun district in the southern region of Sierra Leone. The putative index case, a 35-year old peasant farmer from Kpaku village, Galliness Perri chiefdom, Pujehun district, developed ill-health on 14 March 2017. He presented to a local health facility on 16 March 2017 with fever, body pains, malaise, dysphagia, and enlarged cervical lymph nodes; and was presumptively treated for malaria and sore throat as an out-patient. On 17 March 2017, he developed generalized vesicular skin eruptions in addition to the initial constitutional clinical features. The case-patient was admitted to Pujehun district hospital on 25 March 2017. Biological samples including blood and vesicular swabs were collected on 28 March 2017 and shipped to the National Reference Laboratory in Freetown. The samples were then transported to the Institut National de Recherche Biomedicale (INRB) in Kinshasha, the Democratic Republic of Congo. Laboratory results from INRB relayed on 17 April 2017 to Sierra Leone indicated that the vesicular swab tested positive for Orthopox virus by polymerase chain reaction (PCR) assay and monkeypox virus by GeneXpert technique. Based on these results, the Sierra Leone Ministry of Health notified WHO on 17 April 2017 of the outbreak of monkeypox. Part of the samples have been shipped to the Centres for Diseases Control and Prevention (CDC) in Atlanta, United States for further analysis. Thirteen close contacts to the index case were listed and are being followed up. None of them have developed any febrile illness and/or skin lesions in the first 21 days since the last exposure. The contacts are still being monitored for additional 21 days (twice the maximum incubation period of monkeypox). No other significant exposure risks have been identified except for the fact that the index case, being an occasional hunter, caught a squirrel (a known vector of the monkeypox virus) in the preceding days of his illness for domestic consumption.

Geographical distribution of monkeypox case in Sierra Leone, 14 March - 17 April 2017.

Public health actions • • •

The case-patients received supportive treatment at Pujehun district hospital under barrier nursing and infection prevention and control measures. Psychosocial support was also provided to the case-patient, care givers and close contacts. Active surveillance including case search has been instituted in the affected community. No new case has been identified to date. Social mobilization has been intensified in the affected community to raise awareness on the disease and promote early health care seeking behaviour.

Situation interpretation

An isolated case of monkeypox has been confirmed in Pujehun district, Sierra Leone. This is the second sporadic occurrence of monkeypox in the country, with the first one reported in March 2014 in Bo district located in the southern region of the country. Monkeypox is a rare disease that occurs primarily in remote parts of Central and West Africa, near tropical rainforests. The disease is transmitted to people from various wild animals, including squirrels, Gambian rats, striped mice, dormice, and primates. The natural history of monkeypox virus, the exact reservoir and how it is maintained in nature call for further studies. Secondary spread of the virus through human-to-human transmission is usually limited. This outbreak of monkeypox in Sierra Leone has again highlighted the need for continued strengthening of laboratory diagnostic capacity, particularly for priority infectious pathogens in the region. Similarly, systems for transporting laboratory specimens, both locally and internationally, needs to be strengthened. This is especially critical to reduce the lead time in confirming suspected outbreaks to trigger implementation of effective response measures. The manner in which the country responded to this isolated case of monkeypox demonstrated the gains from the post-Ebola health system recovery being implemented. Although the potential for human-to-human transmission of the virus is deemed low, enhanced surveillance and vigilance should be maintained at health facility and community levels.

2

Health Emergency Information and Risk Assessment

Monkeypox Event description

Central African Republic

2 Cases

0 Deaths

0% CFR

On 15 April 2017, the Ministry of Health of the Central African Republic (CAR) notified WHO of a new outbreak of monkeypox in M’baïki prefecture (district) located at the border with Congo. The initial case in this outbreak is a 15-year old boy from Café-Machado village who developed febrile illness on 12 April 2017. The case-patient presented to and was admitted in M’baïki district hospital on 14 April 2017 with fever, generalized pustular skin eruptions (initially in the palms and feet), and cervical and axillary lymphadenopathies. Biological samples including blood and pus swabs from the skin lesions were collected and transported to Pasteur Institute of Bangui. Laboratory results released on 15 April 2017 indicated that the samples were positive for monkeypox virus using gene amplification PCR technique. Detailed outbreak investigation established that the index case in this outbreak is the elder brother of the initial case-patient who had developed similar illness in the preceding days but recovered without seeking medical care. More information on the activities of the index case is being obtained. Eight close contacts to the cases in Café-Machado village have been identified and are being followed up. Since 15 April 2017, no new cases with similar illness have been identified from among the contacts or in the village.

Geographical distribution of monkeypox cases in Central African Republic, 12 - 15 April 2017.

Public health actions •

• •

A multi-disciplinary team from the Ministry of Health, Pasteur Institute of Bangui, M’baïki health district, and WHO conducted outbreak investigation from 14 April 2017. The team collected the biological samples that led to the confirmation of the outbreak. The monkeypox outbreak response plan has been updated taking into account the emergence of the disease in a new district. Active surveillance has been strengthened in the region including continued support for epidemiological investigation in the health districts.

Situation interpretation

The Central African Republic has confirmed a new outbreak of monkeypox in M’baïki district at the borders with Likouala province in Congo. This is the second outbreak of monkeypox in the country since the beginning of 2017. Between January and March 2017, an outbreak monkeypox was confirmed in Ouango district, Central African Republic, during which 47 suspected and 5 confirmed cases were reported. Ouango district borders the Democratic Republic of Congo and far away from M’baïki. The monkeypox outbreak in Ouango was controlled by end of March 2017. The current outbreak of monkeypox in M’baïki district is thought to have links with the ongoing outbreak in Likouala province in Congo, though the actual evidence has not been adduced. The communities on either sides of the borders in the two countries are homogeneous and have common social cultural activities that bring them together. It is also known that many people from the Central African Republic (including those from Cafe-Machado village) move to Congo for causal works in indigenous farms. Further investigation should be undertaken to establish any potential epidemiological linkage between the two outbreaks. The continuing outbreak of monkeypox in Congo calls for strengthening cross-border surveillance and coordination between Central African Republic and Congo. The health workers and community structures especially along the borders require training in surveillance. Community sensitization about prevention and control of monkeypox should be enhanced.

Health Emergency Information and Risk Assessment

3

Ongoing events Meningitis Nigeria 8,057 745 Cases Deaths 9.3% CFR

The meningitis outbreak situation in Nigeria has quickly evolved in the last weeks with the number of new cases and deaths increasing exponentially. In response to this deteriorating situation, WHO raised the meningitis outbreak to grade 2, based on its Emergency Response Framework grading system. In the last 10 days (from 7 – 17 April 2017), the number of suspected meningitis cases increased by 170%, from 2,997 cases reported in week 14 (week ending 7 April 2017) to 8,057 cases by 17 April 2017. During the same period, mortality increased by 120%, from 338 to 745 deaths. The case fatality rate stands at 9.3%. Majority of the reported cases, 51%, were between the ages of 5 and 14 years. A total of 450 cerebro-spinal fluid samples were obtained from the suspected cases and analysed at the National Reference Laboratory. Bacterial pathogens were identified as the causative agents in 51% (230/450) of the samples. Neisseria meningitidis serotype C was predominantly isolated, accounting for 68% (157/230) of the bacterial pathogens. During the last four weeks, a total of 23 local government areas (LGAs – equivalent to district) have surpassed meningitis epidemic threshold of 10 cases per 100,000 populations. Meanwhile 15 LGAs have attained the alert threshold of 3 cases per 100,000 populations. Six out of 36 states in Nigeria, namely Zamfara, Sokoto, Katsina, Kebbi, Niger, and Yobe, are currently the most affected.

Event description

Geographical distribution of meningitis cases in Nigeria, 1 January - 17 April 2017.

Public health actions • • • • • • • • • •

WHO held a 3-level (WHO Nigeria, AFRO and Headquarters) risk assessment and grading conference call on 20 April 2017. Based on the new grading, a leadership and management model has been established and is being reinforced to ensure effective coordination and response to the outbreak. Active surveillance is being strengthened including conducting daily analysis of surveillance data to identify states and LGAs in alert and epidemic phases. A schedule for distribution of additional medicine and other commodities including Ceftriaxone, rapid diagnostic test kits (Pastorex) and trans-isolate media is being finalized. A laboratory team from Medical Research Council (MRC) Gambia is being deployed over the weekend to strengthen the diagnostic capacity. Human resources needs and personnel deployment plans to the most affected areas have been developed. Immediate deployment to Zamfara, Sokoto and Katsina states have been effected. Reactive mass meningitis vaccination campaigns in Zamfara and Katsina states have been completed while reactive vaccination in Sokoto is scheduled for 24 – 28 April 2017. A national advocacy and communication meeting with various faith-based organizations (FBO) was conducted in Abuja to solicit local support. The Sultan of Sokoto in Kaduna state convened a meeting of the Northern Traditional Leaders Committee on Primary Health Care (NTLC-PHC) on the meningitis outbreak. Production and dissemination of Information, education and communication (IEC) materials has continued and radio jingles are continuously being aired on local radios.

Situation interpretation

The meningitis outbreak in Nigeria has rapidly deteriorated in the last few weeks in spite of the country’s past experiences in managing meningitis outbreaks. The current outbreak has overstretched the government’s capacity to respond effectively, especially at the state and lower levels. The factors postulated for the rapid spread of the outbreak include high numbers of vulnerable population (unprotected) to the bacteria Neisseria meningitidis C, delay in conducting reactive vaccination and inadequate supply of medicines and laboratory commodities. The quantity of vaccines so far received in the country from the International Coordinating Group (ICG) is insufficient to control this outbreak while the approved vaccines and supplies take a while to arrive in the country. In addition, there is insufficient health care workforce to manage the outbreak, especially in the worst affected states. The other critical challenges being experienced in the response include the low rate of sample collection and the limited laboratory confirmation required to satisfy the criteria for vaccines approval, weak coordination of response activities at state level and limited funding to support activities of the National Emergency Operations Centre. Improving response to the outbreak requires strengthening coordination at the state and LGA levels, mobilizing additional resources (financial, technical and logistics), reinforcing active surveillance including case search in the communities and health facilities especially in the silent LGAs, improving reporting and data management to guide the response, building laboratory capacity to confirm cases at state and national levels, and above all, strengthening multi-sectoral collaboration.

4

Health Emergency Information and Risk Assessment

Meningitis

Niger

1767 Cases

115 Deaths

6.5% CFR

This is an update on the meningitis outbreak in Niger that was reported in our bulletin of week 14 (dated 7 April 2017). Since our last report, 1 new district (Dioundiou) that was in alert phase crossed the epidemic threshold by the end of week 14 (week ending 9 April 2017). This increases the number of districts in epidemic phase from 2 to 3. During the same period, 5 new districts [Niamey 1, Niamey 3, Niamey 5, Dogon Doutchi, Birni Koni] crossed the alert threshold, increasing the number of districts in alert phase from 4 to 8. The other districts that remained in alert phase are Gaya, Kollo and Niamey 4. In week 14 (week ending 9 April 2017), a total of 401 suspected meningitis cases including 26 deaths (case fatality rate of 6.5%) were reported across the country. Between 01 January and 9 April 2017, a total of 1,767 suspected meningitis cases including 115 deaths (case fatality rate of 6.5 %) have been reported from 47 districts in 6 regions [Difa, Maradi, Niamey, Tahoua, Tillabéry, and Zinder]. The meningitis outbreak has been confirmed at the Centre de Recherche Médicale et Sanitaire (CERMES) laboratory in Niamey. Of the 1,331 cerebrospinal fluid samples collected, 570 tested positive for bacterial pathogens by PCR. Of the positive samples, Neisseria meningitidis C was the main serotype isolated accounting for 67% of the positive samples. The other pathogens were Streptococcus pneumoniae at 17%, Neisseria meningitidis X at 9% and Heamophillus influenzae at 4%.

Event description

Geographical distribution of meningitis cases in Niger, 1 January - 9 April 2017

Public health actions • • • • •

Outbreak control interventions previously reported including case management, active surveillance and community engagement are still ongoing. On 9 April 2017, the International Coordinating Group (ICG) approved 341,638 doses of bivalent AC meningitis vaccines for the country. Reactive mass vaccination campaigns using the AC meningitis vaccines started on 12 April 2017 in Alléla area in Konni district. The campaign was officially launched on 13 April in Niamey. Training of health workers in Dosso and Maradi regions on active surveillance was conducted based on the Integrated Disease Surveillance and Response (IDSR) strategy. 3-level weekly teleconferences are being held to provide guidance to the country as well as bi-weekly meeting of the national outbreak management committee.

Situation interpretation

The trend of the meningitis outbreak in Niger continues to increase with new districts reporting cases. Three districts have surpassed epidemic threshold while 9 others are in alert phase. In addition, 35 districts have reported meningitis cases below the alert threshold. The continued geographical expansion of the districts reporting meningitis remains a concern. This may be an indication of high susceptibility of the population to the disease. The ongoing vaccination campaign is critical to stop the spread of the outbreak. Unfortunately, the available vaccines at national level is not enough to cover all the high risk districts. The response team need to strengthen early detection of suspected cases, collection of quality sample and laboratory confirmation. This will enhance meeting the requirement to secure vaccines from the International Coordinating Group (ICG). Meanwhile community mobilization need to be reinforced to promote early health care seeking to reduce the case fatality rate. Resources mobilization and partnership are also critical. The main challenges being faced in response to this outbreak include the increasing demand for vaccines and operational funds for reactive vaccination campaigns in the epidemic areas as well as the need for rapid diagnostic test kits (Pastorex) for laboratory confirmation. In the long term, mass preventive vaccination against the emerging pathogens such as Neisseria meningitidis C and other new serotypes needs to be explored.

Health Emergency Information and Risk Assessment

5

Cholera Event description

Democratic Republic of Congo

38,511 1,419 Cases Deaths

3.7% CFR

The protracted outbreak of cholera in the Democratic Republic of Congo (DRC) is still going on unabated. The current epidemic in the country started in August 2015. The situation has continued to worsen with numerous pockets of outbreaks occurring along the Congo River. During week 14 (week ending 9 April 2017), 321 new cases including 10 deaths (case fatality rate of 3.1%) were reported across the country. This shows a minimum reduction compared to 469 cases and 18 deaths (case fatality rate of 4.05%) reported in week 13 (week ending 2 April 2017). Since the beginning of the year up to 15 April 2017, a total of 9,160 cases including 315 deaths (case fatality rate of 3.4%) have been reported. Meanwhile in 2016, a total of 29,352 cases, including 817 deaths (case fatality rate of 2.8%) were notified nationwide. With these, the cumulative number of cases and deaths reported since onset of the outbreak is 38,511 cases including 1,419 deaths (case fatality rate of 3.68%). In 2017, the provinces of Tanganyika, South Kivu, Ecuador, Maindombe, Central Kongo, and Tshopo have been the most affected.

Geographical distribution of cholera cases in Democratic Republic of Congo, August 2015 - 9 April 2017 Week 1 - 14 Week 12 - 14

A total of 1,261 stool samples were analysed at the Institut National de Recherche Biomedicale (INRB) in Kinshasha, 253 of those were positive for vibrio cholerae O1.

Public health actions • • • • •

There is continued efforts to strengthen the multi-sectoral approach to the response to the cholera outbreak. Regular subcommittee coordination meetings are going on at different levels. Active surveillance is ongoing including investigation of cases and active case search in the affected communities. Several partners including ADRA, CARITAS, ALIMA, AGAPE ACTION, and MSF are in the affected provinces supporting case management and infection prevention and control measures. Implementation of water, sanitation and hygiene (WASH) interventions are going on including chlorination at water points, disinfection of water storage vessels, household disinfection, installing handwashing facilities, etc. Continued provision of communication materials, press releases and articles in local newspapers.

Situation interpretation

The outbreak of cholera in DRC that started in August 2015 is not yet showing any sign of relenting despite the enormous response efforts. While being cognizant of the innumerable underlying factors, this may be an indication that the basic critical issues have not yet been addressed. There is need to revamp the entire strategies and interventions to this outbreak. This should come after an in-depth evaluation of the current outbreak response, followed by a new roadmap to contain the outbreak. Notwithstanding, the major challenges being reported currently include inadequacy of funding for operational activities and limited material and logistical resources to continue with control actions at the community level.

6

Health Emergency Information and Risk Assessment

Acute watery diarrhoea/ cholera Event description

Ethiopia

26,966 Cases

731 Deaths

2.7% CFR

The outbreak of acute watery diarrhoea (AWD)/cholera in Ethiopia, compounded by the humanitarian crisis consequent to the El Nino phenomena, remains serious. In week 15 (week ending 16 April 2017), a total of 2,388 suspected cases of AWD/cholera were reported in Afar, Amhara and Somali regions of the country. While some decline has been observed in the trend in the last weeks [4,200 cases in week 14; 4,104 cases in week 13; 4,358 cases in week 12], it is still premature to deduce overall improvement in the situation on the ground, especially with the weak surveillance system. Somali region remains the most affected, accounting for 99% of the new cases reported in the reporting week. Since the beginning of the year up to 16 April 2017, a total of 26,966 cases including 731 deaths (case fatality rate of 2.71%) have been reported from six regions of the country, namely Amhara, Afar, Oromia, SNNP, Somali, and Tigray. Ninety eight percent of all the reported cases and 97% of all the deaths occurred in Somali region alone. On 20 April 2017, WHO elevated the outbreak of AWD/cholera and the humanitarian crisis in Ethiopia to grade 3 emergency. This new grading enables the organization to leverage its global capacity and scale up the response to the outbreak and the humanitarian crisis.

Geographical distribution of Acute watery diarrhoea/cholera cases in Ethiopia, 1 January - 16 April 2017.

Public health actions •

• • • •

On 20 April 2017, WHO held a 3-level (WHO Ethiopia, AFRO and Headquarters) risk assessment and grading conference call and raised the AWD/cholera outbreak and the humanitarian crisis in Ethiopia to a grade 3 emergency. Based on the new grading, WHO Ethiopia has started repurposing the country office staff while surge capacities from the other levels of the organization are being mobilized. The WHO AFRO Regional Office has established the incident management structure for the new grade 3 emergency in Ethiopia. The government is working with partner to develop a 90-day plan of action for the event, taking into account prevention of further spread to non-affected areas. Various outbreak response interventions already initiated on the ground are ongoing.

Situation interpretation

The rapid spread of AWD/ cholera in Ethiopia remains a major concern. This outbreak is occurring in the context of a major humanitarian crisis caused by the El-Nino phenomena. These underlying factors, in addition to the other political, security and economic dynamics, reflect the complexity of the current emergency in Ethiopia. The capacity of the health care system has been overstretched, impacting on the effectiveness of the ongoing response actions. The majority of the treatment centres do not meet the minimum standards and only 50% have access to water supply, thus health personnel and care givers are at risk of contracting the disease and spreading it further. Shortages of medical supplies including intravenous fluids have been reported thus leading to unexpected high case fatality in some woredas (district). Late arrival at treatment centres due to hard-to-reach nature of the predominantly pastoralist communities further increases the likelihood of community deaths. The overall risk of the situation is considered to be very high at local, national and international levels. The health consequences of the AWD/ cholera outbreak in terms of mortality and morbidity on the population has been enormous. Based on these circumstances, WHO upgraded the AWD/cholera and the humanitarian crisis in Ethiopia to grade 3 emergency. This grading will allow the organization to reinforce the incident management systems at both the national and regional levels. The necessary experts are being identified in line with the human resources plan and immediately deployed. Meanwhile the needed funding will be made available for operational interventions. WHO calls upon all stakeholders including the Government, local and international Aid Partners and the Donor communities to join hands and work together to reverse this deteriorating situation.

Health Emergency Information and Risk Assessment

7

Humanitarian crisis Event description

South Sudan

The security situation in South Sudan has remained fragile with ongoing armed clashes in many areas including Wau, former Upper Nile, parts of former Jonglei and parts of Unity state. This has led to increasing population displacements with 1.9 million people estimated to be internally displaced countrywide and nearly 50% of health facilities non-functional. The Integrated Food Security Phase Classification (IPC) technical working group estimated that, by January 2017, 3.8 million people were in Crisis (IPC Phase 3), Emergency (IPC Phase 4) and Catastrophe (IPC Phase 5). Between February and April 2017, the number of people in need of humanitarian assistance (IPC phase 3 and above) increased to almost 5 million, out of which 100,000 were in famine conditions. The highest proportions of populations in Crisis, Emergency and Catastrophe are in Northern Bahr el Ghazal and Unity States. The people facing famine or at risk of famine are mainly located in Leer, Mayendit, Koch and Panyijar counties of Unity State. The internally displaced persons (IDPs) living in informal settlements and their host communities are the most affected by the ongoing conflict.

Classification of food insecurity in South Sudan, 21 Febuary 2017

In week 15 (week ending 16 April 2017), completeness of weekly reporting for routine surveillance and internally displaced persons (IDP) sites were 56% and 79% respectively. During the reporting week, malaria accounted for 26% of all consultations in the routine surveillance sites and 10% in the IDP sites. Malaria transmission remains within expected levels countrywide. Cholera transmission has continued through the dry season. During week 15 (week ending 16 April 2017), 49 new cases and zero death were reported from 3 counties, namely Awerial and Yirol East in Eastern Lakes state and Fangak in Fangak state. As of 16 April 2017, a total of 6,265 cholera cases including 178 deaths (case fatality rate of 2.76%) have been reported across the country. A total of 15 counties from 9 states in the country have been affected since June 2016. In week 15 (week ending 16 April 2017), 35 suspect measles cases were reported from 5 counties. Since January 2017, a total of 560 suspect measles cases including 4 deaths (case fatality rate of 0.71%) have been reported from 18 counties. Five counties confirmed measles outbreaks since the beginning of 2017.

Public health actions • • • •

WHO worked with Partners to provide essential medicines and medical supplies to Jiech, Gorwai, Awerial, and Yirol East. WHO supported deployment of rapid response mobile team to Minkgkaman IDP site in Awerial county, which has no implementing partner on the ground. A total of 1,028,963 children under fifteen years have been vaccinated with polio vaccines in the ongoing polio campaign. In Mayendit town, the rapid response team vaccinated 783 children with measles vaccines, 737 with polio vaccines, 581 pregnant women with tetatus anti-toxoid, and 158 general consultation.

Situation interpretation

The food insecurity situation in South Sudan has been precipitated by protracted armed conflict, the worsening economic situation, and poor yields due to lower than expected rains. Acute malnutrition is a major public health emergency in the country. Evidence shows that, in the southern part of Unity State, one in three children is acutely malnourished. This represents an unprecedented situation requiring immediate actions, especially in Leer, Mayendit, Koch and Panyijar counties. Urgent action is also required for the other severely food insecure areas of the country to protect livelihoods, reduce food consumption gaps and reduce acute malnutrition. Response to the ongoing outbreaks of communicable diseases, especially cholera and measles need to be enforced in spite of the security challenges.

8

Health Emergency Information and Risk Assessment

Summary of major challenges and proposed actions Challenges • Timely laboratory confirmation of suspected infectious public health events is key to initiation of appropriate response measures. The low sample collection rates reported in the meningitis outbreaks in Nigeria and the problem of sample transportation, both locally and internationally, seen in the monkeypox outbreak in Sierra Leone are some of the examples. These key factors lead to delays in confirmation of suspected outbreaks and hence delay in triggering effective response measures. The importance of reactive mass vaccination campaigns as a key control tool is noted this week in the meningitis outbreaks in Nigeria and Niger. Vaccination campaigns are critical to stop the spread of vaccine preventable diseases, however, availability of vaccines in a timely manner has remained a challenge.

Proposed actions • • The Ministries of Health, with support from WHO and other Partners should invest in building laboratory diagnostic capacity for priority infectious pathogens in the African Region including functional sample transportation systems. WHO and the Partners through the International Coordinating Group (ICG) on Vaccine Provision for Epidemic Meningitis Control should continue to advocate for increased stockpiles of meningitis vaccines to halt ongoing outbreaks in a timely manner.

Health Emergency Information and Risk Assessment

9

All events currently being monitored by WHO AFRO Event OUTBREAK Cholera Cholera DRC Tanzania 2 2 1 Jan 2015 04 April 2015 38,511 25,132 1419 390 3.7 1.6 Detailed update given above 9 new cases reported in epi week 15. Temeke municipal council in Dar es Salaam region is the only district still reporting suspected cholera cases for the past two consecutive weeks. 21 new cases reported in week 15. The outbreak has still not been officially declared by the MOH. Data collection for the case-control study to determine potential risk factors has finished. WHO grading assessment undertaken this week, assigned grading level 2. Detailed update given above. Resumption of chlorination activities with the financial support of WHO. A WASH expert has been deployed to support activities. The overall trend shows a slow decrease at country level, however since Epi Week 13 (ending April 2) a sharp increase has been seen in Soyo Patients (mainly refugees) in Diffa presenting with conjunctival jaundice were confirmed Hepatitis E positive. Diffa borders with Tchad where there is an ongoing Hepatitis E outbreak. On 19 April the MOH declared an outbreak. 8 new cases reported during week 11 (week ending 16 March 2017). Domestic spraying at 37 secondary and tertiary institutions is being undertaken in 60 health and social promotion centers in the city of Ouagadougou. Strengthening of surveillance has led to an improvement in detection of cases The situation is abated by the recurrent floods. Outbreak in 13 states Investigations by the deployed entomologist and virologist from IPD determined the recent circulation of the virus and the presence of Aedes aegypti as the vector. 11 new suspected cases between 13/03/2017 – 19/03/2017 from Malanville commune. A total of 40 specimens have been tested between 13 March and 12 April. 12 are positive for Neisseria meningitides C and 1 for Streptococcus pneumoniae. Overall downtrend continues. 20 new suspected cases reported from Wau, Yambio, Tonj North, Jur River, Nzara and Gogrial West. Laboratory results include 46 measles IgM and 36 rubella IgM confirmations. A measles vaccination campaign is scheduled for 17 – 28 April 2017. Measles campaign targeting around 22.5 million children been conducted from February to current Surveillance in affected areas is weak. Training for healthcare workers undertaken, however involvement of communities in reporting cases is needed. 11 new suspected cases between 13/03/2017 – 19/03/2017 from Malanville commune. A total of 40 specimens have been tested between 13 March and 12 April. 12 are positive for Neisseria meningitides C and 1 for Streptococcus pneumoniae. The situation is under control and is being closely monitored. Vaccination campaign in Conakry ended on 17 April 2017. Preparation for a vaccination campaign in the remaining 21 health districts is ongoing. The risk of cross-border transmission remains. A steady increase in cases has been seen since epi week 7. A vaccination campaign was launched by the MOH on 13 April 2017. Deployment of an expert to train people in managing cases and perform active screening in process No update available The Benin Minister of Health declared the end of Lassa fever outbreak in the country on 14 April 2017 in a joint press release with WHO Benin. Enhanced surveillance and community vigilance is being maintained. This event will be closed accordingly. No new cases this week Late referral of cases from communities to health facilities resulting in high case fatality rate. Community sensitization ongoing. Health workers were sensitized on observing infection prevention and control while managing cases. Investigation undertaken by district team. Laboratory confirmation awaited. 36 contacts developed symptoms Outbreak declared by MOH 1 case reported in the last week, CTC set up to manage cases. Presence of the H1N1 influenza virus has been confirmed in 23/29 samples tested at IPD, Dakar. Surveillance is being strengthened 15/04/2017 18/04/2017

Country

Grade

Date of notification to WHO

No. of cases / suspected (confirmed)

No. of deaths

CFR (suspected) / %

Comments

Date of last sitrep

Necrotising cellulitis/ fasciitis Meningitis AWD/Cholera Hepatitis E Cholera

Sao Tome & Principe Nigeria Ethiopia Chad Angola

2 2 3 1 1

10 Jan 2017 20 Feb 2017 Beginning 2017 1 Sept 2016 4 Jan 2017

1556 8057 26,966 1367 (98) 336

0 745 731 15 15

0 9.3 2.7 1.1 4.1

16/04/2017 17/04/2017 20/04/2017 16/04/2017 9/04/2017

Hepatitis E

Niger

-

72

17

24

14/04/2017

Cholera

Kenya

-

10 Oct 2016

235 (36)

4

1.7

16/03/2017

Dengue fever

Burkina Faso

-

29 Oct 2016

2743

21

0.8

12/04/2017

Typhoid fever Lassa fever Dengue fever

Zimbabwe Nigeria Cabo Verde

-

21 Nov 2016 Dec 2016 4 Jan 2017

2572 (95) 283 (99) 98 (19)

10 56 0

0.4 19.8 0

20/03/2017 17/04/2017 09/03/2017

Cholera

South Sudan

-

Beginning 2017

6,220


13

10

14/04/2017

Measles

South Sudan

-

Beginning 2017

515

4

0.78

2/04/2017

Measles Monkeypox Meningitis

Ethiopia Congo Togo

-

Beginning 2017 1 Feb 2017 03 Feb 2017

1100 (496) 32 (4) 376 (28) 5 26 15.6 6.9

02/04/2017

04/04/2017

Meningitis

Benin Central African Republic Guinea Mozambique Niger Cameroon Togo

-

129 (13)

13

10

14/04/2017

Monkeypox Measles Cholera Meningitis Leishmaniasis Lassa fever

-

09 Feb 2017 08 Feb 2017 16 Feb 2017 19 Feb 2017 20 Feb 2017 24 Feb 2017

47 (5) 5262 (3906) 1400 1767 (570) 48 12 (7)

0 19 3 115 17 4

0 0.4 0.2 6.5 35.4 57

04/04/2017 19/04/2017 13/03/2017 14/04/2017 30/03/2017 19/03/2017

Lassa fever

Benin

-

21 Feb 2017

1 (1)

1

100

21/04/2017

Meningitis Lassa fever Anthrax Malaria Cholera Influenza like illness (H1N1)

Cameroon Sierra Leone Tanzania Burundi Malawi Senegal -

9 Mar 2017

25 90 (7)

9 6 0 1170 0 3

36 6.7 (86) 0.04 0 2.5

26/03/2017 10/04/2017 05/03/2017 19/03/2017 10/04/2017

11 Mar 2017 13 Mar 2017 15 Mar 2017 28 Mar 2017

1 2,600,409 18 118

10

Health Emergency Information and Risk Assessment

Event Monkeypox Monkeypox EMERGENCIES Humanitarian crisis Humanitarian crisis Humanitarian crisis Humanitarian crisis Humanitarian crisis Food insecurity

Country Sierra Leone Central African Republic

Grade -

Date of notification to WHO 17 April 2017

No. of cases / suspected (confirmed) 1 (1) 1 (1)

No. of deaths 0 0

CFR (suspected) / % 0 0

Comments Detailed update given above New confirmed case reported in Mbaki district bordering Likouala province in Congo where an outbreak is ongoing. Previous 5 confirmed cases in February 2017 in Mbomou province Detailed update given above Detailed update given above Ethiopia’s on-going drought, acute water shortages, population movements(IDPs) and rising malnutrition, increasing the spread of AWD/cholera. The situation has been regraded as an internal WHO level 3 on 20/04/17. The situation is linked to the Lake Chad Basin crisis. The situation remains fragile due to the ongoing insurgency.

Date of last sitrep

19/04/2017

South Sudan Nigeria Ethiopia Cameroon Central African Republic South Sudan, Kenya, Uganda, Ethiopia, NE Nigeria

3 3 3 2 2 23 Feb 2017

09/04/2017 15/04/2017 16/04/2017

OCHA and IGAD estimate up to 22.9 million people are food insecure in the Horn of Africa. The Government of Zimbabwe has declared the flooding situation affecting 36 districts in the country a national disaster, and has appealed for international assistance. They estimate 251 people killed and 128 others injured by various impacts of the floods. An estimated 100,000 people lack access to safe drinking water Flooding is persisting in the district of Maroantsetra. WHO is strengthening district capacity for coordination of interventions and monitoring of epidemic-prone diseases. US $1 million allocated by CERF to partners in the health sector for the response to cyclone Enawo.

Floods

Zimbabwe

-

02 Mar 2017

Cyclone

Madagascar

-

07 Mar 2017

11/04/2017

Data is taken from the most recently available situation reports sent to WHO AFRO. Numbers are subject to change as the situations are dynamic.

Health Emergency Information and Risk Assessment

11

Data sources Data is provided by Member States through WHO Country Offices via regular situation reports, teleconferences and email exchanges. Situations are evolving and dynamic therefore numbers stated are subject to change.

Editor Dr. I. Socé Fall Editorial Board Dr. B. Impouma, Dr. Z. Yoti, Dr. Y. Ali Ahmed, Dr. F. Nguessan, Dr. M. Djingarey

Contributors Dr. E. Hamblion, Dr. C. Okot, Ms. C. Machingaidze, Dr. S. Dlamini, Mr. A. Moussongo, Dr. A. Oke, Dr. B. Bonkoungou, Dr. L. Omar, Dr. E. Musa, Dr. N. Nsenga Dr. S. Rajatonirina, Dr. V. Sodjinou, Dr. A. Talisuna, Mr. E. Minkoulou, Mrs. E. Kalondo, Mr. T. Mlanda, Mr. C. Massidi and Mr. S. Zielinski Please contact Dr. B. Impouma (impoumab@who.int) for any clarifications.

Health Emergency Information and Risk Assessment

2

REGIONAL OFFICE FOR

Africa

Informations clés
Type de document Journal articles
Date d'adoption
Source Organisation mondiale de la santé