Judgment of the General Court (Seventh Chamber, Extended Composition) of 4 October 2023.#Ascenza Agro, SA and Industrias Afrasa, SA v European Commission.#Plant protection products – Regulation (EC) No 1107/2009 – Implementing Regulation (EU) 2020/17 – Non-renewal of approval of the active substance chlorpyrifos-methyl – Action for annulment – Standing to bring proceedings – Admissibility – Obligation to examine all the conditions and criteria set out in Regulation No 1107/2009 – Absence of an EFSA conclusion – Transparency obligation – Right to be heard – Obligation to state reasons – Divergent risk assessments by the rapporteur Member State and EFSA – Obligation to take into account all the relevant factors of the case – Interim report on an ongoing study – Precautionary principle – Burden of proof and matter to be proved – Manifest error of assessment – Applicability of the read-across approach and of the weight-of-evidence approach – Possibility of relying on the ECHA and EFSA guidelines.#Case T-77/20.