Plan of action and budget for 1987

Onchocerciasis Control Programme in West Africa Programrne de Lutte contre l'Onchocercose en Afrique de I'Ottest' JOINT PROGRAMME COMMTN'EE Office of the Chairman JOINT PROGRAMME COMMITTEE Seventh session Accra 9-12 December 1986 Provisional agenda item 10 JPC .CCP ONCHOCERCIASIS CONTROL PROGRAMME IN WEST AFRICA PI-AN OF ACTION AND BUDGET FOR 1987 COMITE CONJOINT DU PROGRAI}IME Bureau du Pr6sident JPCT .4(ocP/86.1) October 1986 ONCHOCERCIAS]S CONTROL PROGRAMME IN WEST AFRICA ocP/86.1 1 2 3 4 TABLE OF CONTENTS OVERVIEW OF THE PLAN OF ACTION GENERAI CONSIDERATIONS ON THE PROPOSED BUDGET FOR 1987 ESTIMATES BY PROGRA},IME ACTIVITY 4.L Office of the Director . 4.2 Vector control 4.3 Epidenlological evaluation 4.4 Socloeconoulc develoPlnent ... . 4.5 Applled research and environmental nonltoring ""' 4.6 Onchocerciasls ChemotheraPy Project 4.7 Administratlon and SupPort Services Page 3 3 5 10 10 1:l 18 21 23 27 31 344.8 Meetings . ANNE)GS 1. AVERAGE COSTS USED FOR BUDGETARY CALCULATIONS 2. VCU ENTOMOLOGICAL EVALUATION NETWORK 3. NATIONAT STAIF REQUTRED FOR EVALUATION ACCoRDING TO PHASE AND CoUNTRY 4, PERCEMAGE OF OCP STAFF BY COUNTRY OF ORIGIN .... 5. OCP VEHICLES AS OF 31 JULY 1986 ..... 6. VEIIICLE REQUIREMENTS 1987 7. OPERATIONAL AREAS AND EVALUATION ZONES 8. OPERATIONAL PHASES OF VCU 9. PROGRAMI,IE STRUCTURE (AS 0F 1 JULY 1986) 35 36 37 38 39 40 41 42 4J ocP/86. I PaEe 2 TABLE 1. TABLE 2. TABLE 3. TABLE 4. TABLE 5. LIST OF TASLES BUDGET BY PROGRAMME ACTIVITY BTJDGET BY CATEGORY OF EXPENDITURE ...... PROGRAMME BUDGET FOR 1987 - SUMMARY BY ACTIVITY AND CATEGORY OF EXPENDITURE ' OFFICE OF THE DIRECTOR .. oFFIcEoFTHEDIRECToR-SUMMARYBYCATEGoRYoFEXPENDITUREANDBYSECTIoN: Page 6 7 8 11 L987 t2 16 L7 20 22 26 TABLE TABLE TABLE TABLE TABLE TABLE TABLE 12. TABLE 13. TABLE 14. TABLE 15. 6. 7. 8. 9. 10. 11. VECTOR COMROL VECTOR CONTROL - SUMI-IARY BY CATEGORY OF EXPENDITURE AND BY SECTION: 1987 .. ' EPIDEMIOLOGICAL EVALUATION SOC IOECONOMIC DEVELOPMENT APPLIED RESEARCH AND ENVIRONMBNTAL MONITORING APPLIED RESEARCII A}TD ENVIRONMENTAL MONITORING - SIJMMARY BY CATEGORY OF EXPENDITT'RE AND BY SECTION: 1987 . ONCHOCERCIASIS CHEMOTHERAPY PROJECT ONCHOCERCIASIS CHEMOTIIERAPY PROJECT: RESEARC}I CONTRACTS ADMINISTRATION AND SUPPORT SERVICES ADMINISTRATION AND SUPPORT SERVICES - SU}IMARY BY CATEGORY OF EXPENDITURE AND BY SECTION: 1987 27 29 30 32 33 34 TABLE 16. MEETINGS ocP/86.1 page 3 1. INTRODUCTION The second ftnanctal phase ended in 1985 aE a cost of us$ 106'9 m111ion' This included development of a long-Eerm strategy to gulde the Progranne towards atE'ainment of its objectlve, naoely, "Io ellninate onchocErciasis as a disease of publlc health and socloecononic lmportance throughout the Programme area and to ensure that there is no recrudescence of the disease thereaftei". itso Uy the end of 1985 a Plan of gperations with ;;;iii;;-"i us$ 133 rnillion had been approved for the third financlal phase, 1986-1991' 1986 was the flrst year of the new financial pha se and witnessed lntensive preParations being nade ln the Western Extenslon area to enable larvicidlng operatlons to begln there (Phas e VI) as well as in the Southern Extension area (Phase V) in 1987. Trials were undertaken to evaluate the effect on reinvaslon of the treatment of these extenslon rl'vers on reinvasion; the results hrere positive. However, the year also saw a spread of resistance to Eemephos of savanna specles of the S. damnosum ccmplex' This required a drastlc modiflcation In larviciding strategY towards the rotational use of the five products avallab1e as a result of the long- terrn screening of the range of candidate coupounds provided by the chemical lndustrY. Teue phos, chlorphoxlm, the new HPD formulatlon of Bacl1lus thurl sis H-14, permethrln and carbosulfan were all used in accordance wlth t recommenda tlons of the Ecological GrouP and the Expert Advlsory Co 'nittee. This, of course, had budgetarY lmpllcations as had the fluctuation ln the United S taEes dollar. 1986 also saw the selection of a new aerial spraylng contractor as a result of lnternatlonat competltlve biddlng and the constructlon of an aerlal base at odienne ln C6te drlvolre from where he will operate, to replace that at Bobo-Dioulasso 1n Burklna Faso' The reposltloning of the main aerlal base wl11 facllitate the servlclng of the new llestern Extension areas uore effi.clently. The 1987 plan of Actlon and Budget has been drawn up with a view to loalntalnlng scheduled progress towards achievlng the objectlve of the Programne wlthln the speclfled time. To thls ena ite budget 1eve1 has been lncreased to us$ 29 934 000' The provislonat projecrlons for 1988 and 1989 are US$ 29 500 000 and US$ 22 0OO 000 respectively' 2, OVERVIEW OF THE PLAN OF ACTION In 19g7 the general policy of the Programme as presented in the Long-Tern SErategy and in the plan of operattons for the third financial phase wt1l be followed wlth enphasis on the extension of the control operatlons to the west and south. The spread of resistance has added a new burden on t.he Programme which, although not unforeseen, wl1l requlre larger quantltles of alternative products to be applled and hence an increased number of flight hours. However, thls should be counterbalanced by the resultant curEallment of reinvasion, but the operatlonal savings which should result therefron w111 not be realized frou a budget polnt of vlew until 1988. The spread of the resistance phenomenon has slgnalled agalnst a too rapid decrease ln the entoroologlcal evaluatlon network tn the orlglnal areas. AccordlnglY, the pace of thls reduction is betng rationalized ln line with iniormation required from present resistance foci and posslble rlsk areas. 1n line wtth the policy to malntaln and, where possible, improve the cost-effectiveness of the Programme and its oPeratLons, coordinatlon of the aerlal oPerations w111 be transferred under the direct supervision of the Dlrector. A1so, wit.hln the aerla1 spraying contract, a light, llalson aircraft will be available to facilltace communlcations throughout the Prograrr. .t"" and rePlace the use of vehicles, thereby luprovlng efflctency' The proven efficacy of the Argos systeo using satellites for transmitting river discharge data which can be used to determine dosage levels at tlne of treatment has deterrnlned that the net\rork should be extended signiflcantly. Concomitant with the extension operatlons will be the consolldation of the success already achieved Ln 9QZ of the origlnal Programme area and PreParations to devolve responsibillty for maintenance actlvlEies in selected areas where onchocercLasis wl1} cease to Lu a probleo to the Partlclpating Governments concerned. In thls latter respect a start is anticipated in 1987 to the implementation of plans for dev<.rlutlon of relevant OCP activltiei to the authorlties in Burklna Faso, Mall and Nlger. ocP/86.1 Page 4 In the VJestern Extenslon areas, use will be made of national personnel pald by their Governments as proposed tn the plan of operatlons and these will be actively lnvolved in the operaEions ln 1987. Trainlng w111 be lntenslfied considerably to help the PartlciPatlng Governments provide the staff of dlfferent disclplines necessary to carry out the malntenance oPeratlons "rrU""qrr.rrt to OCP. Natlonal staff for Phases VII and VIII will also be trained. Co nunlty trlals wtll be undertaken in the OCP area wlth the new, long-actlng rolcrofllaricide, ivermectln, prlor to its anticipated introductlon for general clinlcal-use some time after its reglstratlon tn mid-1987. ExEensive pre-cllnlcal trials of a candldate macrofilariclde are aLso planned. Both these drugs result fron the Onchocerciasi-s Chemotherapy proJect which w111 be subJected to an lndependent reviel in 1987 to determine lts future role and fundlng requlrements. Epideolological and socioeconomlc deveJ-opment data w111 contlnue to be collecEed ln the Western Extenslon area as a basis for comparlson ln later years and the statlstical analysis of all entomologlcal and epidenlologtcal data pursued. The computerlzlng of VCU aerlal operatlonal data w111 be lntenslfled. The followlng summary of proposed actlvlties s111 provlde the framework for the Plan of Actlon presented here: - the lmplenentatlon of conErol oPeratlons ln Phases v and VI; - the PreParatlon for Phases VII and VIII; - the elfuninatton of relnvaslon ln the orlginal Programme area; - controlllng and preventing the spread of reslstance through the rotatlonal use of the flve larvicides avalIable; - consolldatlon of activttles ln origLnal Programme area; - nalntalnlng research on new larvicldes, the blology of the vector and parasite and an lmunodlagnostlc test; - coordinatlng field trlals with lvernectln; - pursulng vigorously the search for a oacrofllarlcide and carrylng out clinlcal trlals wtth candldate conPound; - undertaklng a revlew of the Onchocerclasls Chenotherapy Project; - deterulnatlon of the epldenlologlcal sltuatlon in Gulnea, Slerra Leone and Gutnea-Blssau and also ln rrestern Mall and eastern senegal; - continued evaluatlon of the decline ln endemiclty ln the original Programrne area; - collectlon of baslc socioecononlc data in Western Extension area; - pursuance of plans for devolution with the Partlclpatlng Governments; - traintng of natlonal staff froo Phases VII and VIII for the oPeratlons; - Erainlng of natlonal staff frou orlginal Programme area to assume relevant maintenance actlvlEles when these are devolved ln accordance lrith the plans prepared by the ParticlPating Governments . ocP/86. r Page 5 3.GENERA],CONSIDERATIONSONTHEPROPOSEDBUDGETFORl9ST The preparation of an oCp plan of Action and BudgeE must take into account the biology, dlstribution and behaviour of the vector as lnfluenced by the vagarig: of climate and environment from year to year. However, as on previous tccasions, this Plan of Actlon and Budget has been drafted on the experlence garlgg not- only from the beginning of the Programme but also, and in particular, from events ii fgAO. The operafions are mov1ng in 1987 into new Eerritory where, desplte reslstance' continued operational success must and will be assured' It has been consla"i"a pertinent, therefore' not to talce unnecessary rlsks by reduclng activities elsewhere too soon. The budget for 1987 has followed the procedure of zero-based budgeting. It reflects the operations, needs expressed ln the-plan of action of the <llfferent technical units as well as the estlmated expendit,rru of the office of the Direetor, the Adninistration and Support Servlces and statutorY meetings' The tables have been prepared on the basis of carefully calculated cost estimates which take lnto account the tremendous changes which have characterized the world econornic situatlon in recent years. The instaf,ility of the United states dollar has resulted ln many fluctuations in the rates of exchange of the main currencles used in the Programme' This situation has had an unfavourable iipact on the implementation of activitles generally' The estimates have been developed nalnly on the budgeting procedures adopted by the I{orld Health organization. Established average costs are shown in Annex 1' with regard to the personnel of the General Services category, a thorough review was made of Ehe actual "*p"rriltrres incurred at Ehe time of preParation of the budget. rt was thus possible to reduce sllghtly the base average cost for 1987 as compared with the averaSe used for 1986 by taking Lnto account the vacancy rate ln this category of staff' However, t.he average arrived at had to be adjusEed uPwards to take account of the fluctuatlon in the rates of exchange whlch in the case of the crA required an increase of no less than 302' The national personnel to be used ln the Western Extenslon area will be given an incentive payEent not e*.uedlrlg 252 of the net sa1-ary paid by their countrles' As regards the other estlnated costs, they are based on the prlces prevailing 1n June 1986. The budger proposed for 1987 torals us$ 29 934 0oo. Although the original proJection for 1gg7 ar the ttnl ot prepararion of rhe 1986 budget amounted to us$ 25 9O3 000, by the tlne of the meeting of JPC in December 1985 the Plan of operations for the third financial period recognlzed ihe need for the budget leve1 f.or 1987 to be US$ 27 415 000' Developnents in the world economic situation have hld Eo be taken into account ln order to ensure delivery of the progralpme as envlsaged ln the Plan of Operatlons, and to thls effect the proposed level tir lgil had ro be lncreased to us$ 29 934 000' It wlll be noted frorn Table 1 that notwithstandlng the substanttal increase for 1987 the percentage dlstribution by Prograrome activity for the biennlum 1986-1987 is much the same as was foreseen ln the 1986 proposed Plan of Action and Budget. An explanatlon of the increases required in 1987 as compared to the approved budget for 1986 is 81ven under each of the Programme activities throughout the document' ocP/86.1 Page 6 TABLE 1. BUDGET BY PROGRAMI'{E ACTIVITY Percentage of total 1986-1987 Total for r_986-1987 Approved 1986 Proposed L987 Progranme activitY 7. 4.6 6L.7 2.9 1.0 7.0 8.9 L.2 us$ 2 457 000 32 776 000 1 564 000 s15 300 3 711 400 4 740 800 630 000 US$ 992 000 13 705 000 730 000 240 000 1 810 000 2 160 000 310 000 us$ 1 465 oOOl 19 071 oOO2 834 000 275 300 I 901 400 2 580 8003 320 000 87.346 394 50026 447 sOOL9 947 000 L2.76 751 5003 486 5003 265 000 Offlce of the Dlrector Vector conErol Epidemlologlcal evaluat lon Socioeconomlc eval-uatlon Applled research and environmental nonl torlng AdninlstratLon and Support Services Meetings ChemotherapY Project Sub-tota1 100.053 146 00029 934 00023 2L2 000TOTAL Detalls of increase given on page 10. 2 D"a.il. of increase given on page 15. 3 D.a.il" of increase given on page 31. ocP/86 .1 page 7 I TABLE 2. BUDGET BY CATEGORY OF EXPENDITURE RECURRENT COSTS Personnel services Consultants Operational travel Aerlal oPerations Research contracts Contracts (other) Operating costs Insecticldes Supplles Fellowshlps and tralning Local cost,s subsidies Meetlngs Sub-tota1 CAPITA]. COSTS Buildings Furniture Vehicles Equipment Sub-total TOTAL 1 lrr"r"."" due to US dollar fluctuation, statutory wage lncreases' staff for extenslon oPeratlons r etc. 2 lrr"."."" due to lmplementatlon of extenslon operations and addltlonal fllght hours for applicatLon of B.t. H-14. 3 Ir,"a".". due to necessary purchase of larvicldes additional to teoephos on account of reslstance. 4 rr,"t"."" necessary to meet the denand for tralning froro Partlcipatlng Governments' Category of exPenditure Approved 1986 Proposed ]-987 Total for 1986-1987 Percentage of total 1986-1 987 US$ 6 330 000 760 000 922 000 4 360 000 3 600 000 75 000 2 t_50 000 2 400 000 540 000 105 000 435 000 US$ 8 431 5001 762 500 938 000 5 715 o0o2 3 880 000 1 580 000 5 446 0003 635 000 300 0oo4 350 000 390 000 US$ 14 761 500 \ 522 500 1 860 000 10 075 000 7 480 000 75 000 3 730 000 7 846 000 1 175 000 405 000 350 000 825 000 /" 27 .6 2.9 3.5 19 .0 14. 1 0.1 7.O 14.8 1'.) 0.8 0.7 1.6 2t 677 000 28 428 000 50 105 000 94.3 235 000 137 000 618 000 545 000 155 000 113 000 470 000 768 000 390 000 250 000 1 088 000 1 313 000 0 0 2 2 7 5 0 5 1 535 000 1 506 000 3 041 000 5.7 23 2L2 000 29 934 000 53 146 000 100.0 ar{(! 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(Y) co !F{oo r)tr OIJ0rtr>o o IIooooooooooooooooooooooooooo @e.lounoo\oooCO-lO'-{toO.fr^O6 N \O r\ N.f, (O.S (O tn F{ !n 4 a :) ooo F{\o o\ N F.l oooooooooooo ooooO\OO!nFl .+ rn ooo o F.{ F{ F.{ ooo F.lt\o Oril q) El]EO(!u l]o @0JOlrl.t 'r{ora ooo roo I r oo Iooo oo oo\"\OO OO OO cid)rn 06 oo co\or.- (.)(n cio@ (rl a (,n ooo F\ F.l .$ FI oooooooooooo rod)oo F-.{ (f) ooo co .i. ooo !n\o\, F{ o,tl a r, ..{ € c oa x o o >'! o @ 0)U(!(J hu .H ..i u o EI HoH ri(! IJ ou I4 a(t) ri o EA Ft u o (,)o F{ @fr u, dtrroo .r{ r, F{ .Fl noFt o tr F-.r 6 .r{ .C ..{ L{ -C q) ,roc,lalq>H tn H U)oq) FI HH o{ () F{(! +J U Ip V) @ ;OQO"{ .f{ (!(nFlltro oo '.{ uo >1, @ .Fi r00 o I ! > rr.r{ rJ a dtr UrJ tD O do (! 0u)O O.i lr O O) O q +rdo'E,.Jo. -r C d O. o O0.-l o F{o6ooutroo(a.dotr +J.H O.r{r{ o o (,) o0tr-rrJFl tirJ! +{}dO, cU tU l. G UF{FI O'.{O O tr.H U ! O $ OF{ utr tr 0, rr tr o o o O.Fl 0)o o o.o o o.tr o 5 0) (uAi(JO<()OHFI(/)T!E aH at) o(J Hz frfd& o trl& ocP/86. I Page 8 EI&DFHAz Idp{ X rIl tro &o() frlH (J Az ts E{H r{H C) ts ro & a U) I FT @ o\ ,{ &oh tsfrl(J o ca frt e 4&(J o& o{ C7) ld FI FA H ltltlll I I ocP 186.L Page 9 F\ c, s9 ER z6 oror so 9oroFo >e , F tro [! = CE(9 oG o- co T\ @I CE o LL [!trlF oz ul o-x UJ o[!F =trU'tlI uo! \q"\ 3'"J^fi'S3'(11 6%) t"$3'* $ co\\ co bci.sx-o .._- v ;-o' .9 I o.d6a.,g .-o\5 o-EE'Q-\-.s-F $$ ."S' co E o. -9o €s :otrO^git olJ)O 1.. '6N3* o\ 44 ocP 186.L Page 10 ESTIMATES BY PROGRAM}IE ACTIVITY 1 Offlce of the DlrecE.or As in 1986, the office of the Director will be responsible for: general pollcy and manageoent of the Programme; I-iaison wlth statutory bodies' governments and the sclentific "o*I"fty; analysisr-coordination and evaluation of actlvities; information; and coordination of r.""i'."t. In 1987, responsibility for the overall supervision of the aerial operatlons will be transferred fron the Vector Control- Unit to the Office of the DirecEor, wlth one professlonal in charge, in order to more closely coordinate these oPerations ln- the extended prograume area, east-a.td *e"t, and to ensure the fleet of aircraft is used ln the most cost-effectlve manner. The office of rhe Dlrector wlll also, wlth the WHO Regional Offtce for Afrlca, assist Burkina Faso, Mali and Niger in the PreParatlon of their plans of operation for devolutlon. The statistics section will be strengthened ln order to carry out more activities than ln the past, with an integrated analysis of the epidemiological, entonological and socioeconogic data, and the continuaEion of support for research on epidemloruetric nodels. The Informatlon Service will contlnue its campaign of pronotlng the Progranme alned princlpally at the general public, on the one hand and the donors on the other through all availalle neans (press, f1los, exhibltions)' In line with the greater response from Ehe Participating Governments to the tralnlng of national staff not only for the oPeratlons but also for assuming responslbillty for maintenance actlviti""r. substanilal increase in the funds avallable for fellowships and tralnlng w111 be requlred. For the executlon of all these tasks, the Office of the Director comPrlses; - 11 Professlonals and 15 General Service staff' Provlsion has been made for 12 man-oonths of consultants. The increase of US$ 472 800 is requlred to cover a post of sclentist for coordinating aerial operations (US$ 80 000) transferred from.VCU, statuEory increases and adJustment for the rate of exchani" iUS$ 153 200), additlonal operational travel to cover a wlder seoeraphical area ior'"orptising ii countries (US$ 15 000), additlonal fellowship and ;;;i;;;-iuig-igl 000) and orher requirements in respect of consultants' contracts, supplies' operati;g and capital costs (US$ 44 600), partly offset by a reductlon for meetings(us$ ls ooo). 0cP/86.1 page 11 TABLE 4. OFFICE OF THE DIRECTOR Proposed 1987 Approved 1986Grade Posts 1985 1987 Category of exPendlture 80 000 80 000 80 000 B0 000 80 000 80 000 60 000 60 000 60 000 us$ 60 60 28 4 9 24 4 31 000 000 800 800 600 000 800 400 US$ D.2 P.5 P.5 P.5 P.4 P,4 P.3 P.3 P.3 P.3 P.2 G.S G.S G.S lr.D G.S 1 1 1 1 1 1 1 I 1 1 1 5 1 ? 5 1 883 400650 00025 26 63 75 30 35 30 300 600 000 000 000 000 000 60 000 60 000 25 000 30 000 000 000 000 25 105 15 533 600320 000 5 000 3 000 10 000 30 000 2 000 20 000 48 00022 000 1 465 000992 00025 26 Programme Director Coordinator Medical officer Sclentlst Statistician Sclentlst, aeronautic liaison Statistlclan Admlnlstratlve offlce Technical offlcer Information officer Adnlnistratlve of f lcer Adnlnlstrat lve assistant Secretary Cartographers Clerks, stenographers and typists Drlvers Temporary staff Consultants Operatlonal travel Contracts (other) Operating costs Supplies Fellowships and tralning Meetlngs Sub-tota1 Sub-tota1 Sub-tota1 TOTAL CAPITAI COSTS RECURRENT COSTS Personnel services Buildings Furnlture Vehicles Equlpment F{6 IJ o ts oooooooooooooo .r}\OOOOOO (7)(nl^0L^oo cO\OF-(n(V)f)O co (n 4 U) ooo r\ FI\' F{ oooooooooooo rnd)oo Fi (o ooo @\? ooo tn\o .J' -{ (utr >oooC+{o6()r{ FI o I o ooo o oo@ o oo t.r\ rn tn rn r\ Fl FI 4 .J) oo @ ooFI rtlt oo @ ooN oaoodtrEt{oE trI c-ro(!(0 F{ tl F{ +J o) t& ooo oo(Y') .C) a ;f ooo oo(f) ltlt ooo oo(n o o .|., o !(! TJ U) oooooooooooo rnor^o Fl d) F.l F{ ooo -toN 4 u, oo @ .f r\N lolooooo c)o 6t ooo (') al oo co r\ cN troO +.1 r{rJ rJ66!! edtlr(nOOEr.ratroHO t oooooo oo Fl Fl oooooo\OGIO O\F{rl1\O cl a a ooO F.{ F-{ ooo Itt ooo rn oo @ oN F{ orJtrECOEl o .'.1(BEU liOr,@ @-l o(!0t{tr>o{(!0,Et oooooo tt !n ooooooc\r.f o(')No c) .S .+ .$ 4 ap oo\o 6ltn oo\o tjt .d' rn ooo oN oooooo Orn Fl ooo 1r) o,)lr a! 1, o o. X o o >t H o @ o +J6() d o .J (,) oa ,.1 tso ts F{(! ! oU Ip a U' o0, rJo0rr (,, trtrr0ro ..{ uFl E rjFl O O.F{ tr .''l .'{ ..{ l],E ',ro('lQfi>frl ati v)oo .t tsH A (J F{ (U U o ! Ip aa (n -{oo,o>r.{tUo >l{.Jll{uoooo oFl O o .1(!AF{dtrou0 ..1 o (! 0 u c oE ctrF{o+{ootr'-{rrtUrt.d}Ort0l'tdr-{O oo!uHO.FlH tr O tr O AF{o o ao a, c,Or()O()OU)lq aHao c) Hz EIdd o rdd ocP/86. 1 Page 12 r\ @ Or F.{ zoHHq) rd(t, F EA az frldp tsHoz frlAx rtl ho >{doo rIlH o Ilq Fil E IA I &oH C) lrl&HA rJ] H tqo fr]q) H fr{fro lrt f,I .l FA ts ltl 0cP/86.1 Page 13 4.2 Vector control The year 1987 w111 be marked bY: - the implementation of the extensLons to the South - the containlnent of larvicide resistance as far as savanna species; - the 1lke1y terroination of reinvasion of the vector Control operations control activitles will be directed against savanna speclesr lncluding those occurring In the forest 1f they constltute either an epideniologlcal risk or a potentlal source of invasion. larvicldes, B.t. H-14, temephos, chlorphoxlm, Permethrln and carbosulfan, wili (Zone V) and to Ehe West (Zone VI); is possible, esPeclallY anong lnEo the lnitlal Programme area. Ihe flve be used. tr{ith regard to larviclde reslstance, three zones can be dlstlnguished: - Those in whlch resistance to tenephos has not yet been deEonstrated and where the risks of its appearance are, a Priorl, limlted. Here, temephos v'il1 be used in the wet season but will be progre@replaced by q:-t. II-14 durlng th9 dry season' In rhe Wesrem e*ten"1o"-"i."] the altlrn"iiot of tetE-phos and L!- H-14 will be progra med in such a way as to ensure that treatment costs are kept 1ow, whlle at the ".ri tir" dolng everything posslble to llnlt the development of reslstance' - Those where resistance has not been demonstrated but where the risks of lts developing are a priori increased. This is, for example, the case in certaln parts of the eastern operational area and of the Southern Extenslon area' Ilere g+' 11-14 will be exploited to its maximal capacity until rlver discharges reach approxinately 7O n3/s. Above that 1lnit temephos w111 be used' - Those of conflrmed reslstance. Here, B.t. H-14 w111 be used as in the prevlous case. In larger river discharges and ln relailLon to the type of resistance and to lts posslble evolutlon, conblnatlons of chlorphoxlmr Pemethrin and carbosulfan will be utillzed. The tntioductlon of such a combinatlon inplles a strict follow-up of the resLstance, the acqulsitlon of preclse hydrologlcal datar and the taklng into account of all the varied f""to." whlch can infllence ihe development and evolutlon of resistance, ln both sPace and tLae' In the speclal case of the buffer zone between the origlnal Prograome area and the western Extension (zoae vI-1) organophosphate insecticides w111 not be used, ln order Eo linit the rlsks of resistance lncreaslng and spreading towards the west' Operational tactlcs Treatment operations will be nost intensive durlng rhe two seasonal transltlon periods which nark the beginning and endlng of the wet and dry seasons. By ensuring naxlnal coverage durlng these pert6as it should be posslble to interrupt treatments at times of both very 1ow and very high water levels. Hydrographical situatlons which constitute potential sources of invaslon will becone the objects of increased surveillance and of reinforced treatment coverage. The initlal programme area will contlnue to be regularly treated. It w111 not be posslble to commence any further curtaLlment of treatments untll the extensions have been irpt"r..,t.d and shown to be effectivel probably frorn t,he beginning of 1988' The Southern Extension area (Zone V) wt11 be under fu1l control from the beginnlng of L9g7. The proposed control strategy for that zone is based on the distribution of species, on thelr mlgratlon capaclties, and on treatoenE difficultles especlally in mountainous regtons. ocP 186.L PaSe 14 In the Western Extension area (Zone VI) has been divided into three sub-units. Zone VI-l has already received atEention. Zone YI-2 (River Senegal basin in Mali) has been extended as far west as Kayes and will be t.reated entirely wLth temephos durlng 1987. In Zone VI-3 the attack phase will be lmplement,ed in two stages over two years. In the absence of a sufficiently extensive hydrological network, treatments during 1987 will be deslgned unlquely to prevent invasion of the rrestern flank of the initial Programme area (treatments trom Uaictr to July, essentially wlth B.t. H-14). Treatments lilil1 be resumed deflnitively and xoore intensively during Ehe dry season of early 1988' Aerial operations It ls proposed to utilize to the maximuu between nine and 11 helicopters and one and two Turbo Ihrushes, dependlng upon the season. The total numbers of flight hours have been estlmated at 10 000 for the fleet of aircraft. To attaln these objectlves within the context of Ehe neld aerlal conEract, the alrcraft w111 have to be used to thelr maximum potential. Treatuent circults will have to be carefully arranged and planned to ensure the best cost/efficlency ratior while also respecting establlshed security criterla. Entonologlcal evaluat lon Survelllance in the lnit.lal Prograrnme area w111 wltness little ehange compared to that of 19g6. Reductions in the evaluatlon network w111 not coEe into effect until perlpheral and invaslon areas have been brought under complete control. Trapplng actlvities will be lntens1f1ed. Manual, ground treatmengs w111 be contlnued (Bandlagara) and will be extended to other localities (Farako and uPPer Black Volta). In the Western Extension zones, evaluation will be the resPonslbllity of national teans; breeding slte checks wtll rely heavily on the use of hellcopters' Entonologlcal daEa w111 be received and explolted at the headquarters of the evaluatlon zonesr as well as at Programme headquarters in Ouagadougou' Hydrology The inplenentatlon of the extensions and tenephos w111 requlre that serlous efforts be networks and for inproving the precLsion wlth avoid dosage errors which could be costly and the utilizatlon of alternatlve larvicldes to made for the refurbishlng of hydroJ-oglcal which discharge rates are neasured, in order dangerous to the environment. to The re-establ-ishmenE of the Guinea netrsork ln Zones vI-3, vlr and VIrI relies especially upon a close collaboration between the national hydrology service and ORSTOM. The situation tn Sierra Leone will be evaluaEed in November 1986' The collection of preclse data will be possible thanks to the utillzation of Argos teletran6misslon beacons; these latter, especlally in Guinea, will resolve the problem of access to the statlons. For the whole or tt," Programme, 40 Argos beacons, of whlch 34 are equlpped with Chloe-Elsyde probes, remain to be ordered for 1987. RequLrements for Zones VII and VIII will be assessed at the end of 1986' Wit.hin the framework of the hydrological network kept under peroanent surveillance ln the progragrme area, lt 1s planned to traln and equlp 10 sub-secEor chlefs who w111 then be able to assume resionsibility for 1ow water level gauging. Two hydrology brigades wlll also be createdr one at Odienne and the other at Kara' The hydrology engineer w111 be responsible for exploitlng hydrologtcal Lnformatlon obtalned fron the teletransmLsslon network and for adaptlng lt to Eeet the requirements of the aerial operations bases. He will also coordinate all hydrological actlvitles, especially with regard t.o natlonal hydrology brigades. 0cP/86.1 page 15 Personnel In 1987, Personnel- requirements will be: - Professlonal staff 27 - General Servlces 435 National personnel who wilt work for the Programme and to whom ocP will pay a salary suppleoentandperdlemwtlltotal42Lasfollows(seealsoAnnexS): - scientif lc/nanagerlal - technlclans - drlvers, radio oPeratorsr etc. - vector collectors, labourers, etc. 8 115 727 177 Of the increase of US$ 5 366 000 an amount of UQ$ 838 000 is required for personnel servLces as a result of: - an adjustment to the esti.Dates because of rates of exchange (us$ 487 2O0); - statutory cost lncreases (us$ 107 800); - provlslon for professional posts expected to be ln positlorr by 1987 and for which a delay factor was applled in 1986 (uS$ 300 000); - provislon for temPorary staff (us$ 60 000); - reiluctton in General Services posts and Eransfer of a Professlonal post to the 0ffice of the Programme Dlrector (Us$ 117 000). An lncrease in consultant oonths (US$ 32 000) has been provided to iroplenent the VCU programme. The total number of consultant EonEhs will therefore be 40, to be used in the aerial operations, hydrology and general VCU actlvities' The aerial operations requlre an estimated 9000 hours as agalnsE the provlsion made ln 1986 for 7800 hours. As a result, an lncrease of US$ 1 355 000 has been provlded' uii OO 000 is also lncluded to cover the cost of the llaison aircraft lncluded In the contracg and for whlch provlsion was previously nade under admlnlstration and management' provisLon is made for incentlve payrnents to natlonal staff to be detached to the Programme (US$ 350 000). An increase of US$ 3 046 000 is included ln the 1987 proposed budget for lnsecticides to cater for the needs of the Prograrme taklng lnto account the Southern and Western Extensions' An lncrease of US$ 100 OOO ls provLded for supplies nostly ln order to equlP the new zones of the programme (Kara and Bamako), lncluding rehabilitatlon and extenslon of the radlo ;;;;;rk; ."a us$"rso 000 for equlpnenr for the purchase of replacement sPare Parts for the vehlcle fleet. The above increases totalllng US$ 5 931 0OO are offset by a reductlon of us$ 565 000 in theprovlsionsforoPeratlonalcosts,ueetlngsandbulldlngs. ocP/86. 1 Page 16 TABLE 6. VECTOR CONTROL Category of exPendlture Grade Posts Approved 1986 Proposed t987 1986 L987 PSCURRENT COSTS Personnel servlces Scientlst.s Technlcal officers Adulnlstrative ass lstants Clerks, stenographers and typlsts Technlcal asslstants DrLvers, vecEor collectors & others Temporary staff Sub-tota1 Consultants Operatlonal t.ravel Aerlal operatlons Contracts (others) Local cosEs subsldles Operatlng costs Insecticldes Supplies Meetlngs Sub-tota1 CAPITAI, COSTS Buildlngs Furniture Vehlcles Equlpnent Sub-tota1 TOTAL P6/P4 P3IPL G.S G.S G.S G.S 11 L6 3 16 80 336 US$ us$ 880 000 960 000 14 400 76 800 384 000 1 612 800 60 000 476 462 3 150 000 3 988 000 180 000 600 000 4 300 000 50 000 1 700 000 2 400 000 300 000 15 000 2L2 000 600 000 5 715 000 50 000 350 000 1 200 000 5 446 000 400 000 9 545 000 13 973 000 150 000 60 000 400 000 400 000 100 000 60 000 400 000 550 000 1 010 000 1 110 000 476 462 13 705 000 19 071 000 ocPl86.L page 17 TABLE 7. VECTOR CONTROL - SUMMARY BY CATEGORY OF EXPENDITURE AND BY SECTION: L987 Sec t ion Category o expendlture Management AerialoPerations Entonologlcal evaluatlon Total RECI'RRENT COSTS Personnel servLces Consultants Operatlonal travel Contrac t s Operatlng costs Insectlcides Supplies Natlonal teams Aerial operations Sub-tota1 CAPITAL COSTS Butldings Furnlture Vehlcles Equlpment Sub-tota1 TOTAI us$ 550 000 79 500 77 500 50 000 36 000 40 000 US$ 1 100 000 55 000 144 000 5 446 000 80 000 5 715 000 US$ 2 338 000 132 500 467 500 1 020 000 280 000 350 000 US$ 3 988 000 212 000 500 000 50 000 1 200 000 5 446 000 400 000 350 000 5 715 000 833 000 12 540 000 4 588 000 17 961 000 50 30 000 000 25 000 10 000 70 000 70 000 75 000 50 000 280 000 450 000 100 000 60 000 400 000 550 000 80 000 175 000 855 000 1 110 000 913 000 12 715 000 5 443 000 19 071 000 ocP/86.1 Page 18 4.3 Epi demiological evaluation The following prioriEles are established for 1987: (1) strict collaboratlon between vcu, EPI and ECo in the planning and executl'on of the varlous actlvities and sEudles; (li) cholce of villages for evaluatlon of vector control and specific studies in the Western ExEension; (iii) routine quality control tests; (iv) special studies on: (a)theeffectofinterruptlngvect'orcontrolatFarako' (b) mlgration, (c) the need of a more sensltlve dlagnostic procedure' (d) comparison of the sensltivity of dlfferent paraslEologlcal examlnations; (v) devolutlon: PreParation of manuals of procedure and tralning of national teams' 1og1cal survelllance TheobJectlvesoftheepldenlologlcalsurvelllanceare: (1) to assess the success or failure of vector control on the human populatlon; (il) to study the evolutlon of the disease during vector control' villages being selected in coilaboration wtth VCU and the Statistlcal Unit. The routlne epLdemiologlcar surveillance of the 140 vlllages in the original area w111 contlnue. Approxirnately one-thlrd of these villages wlll be followed up in 1987' six of which w111 undergo detailea "r.t,r.tiorr. A special effort w111 be nade to maxlmize villagersr particlpati.on to avold loss of cohort and seml-cohort members. Quallty control tests wil-1 be conducted to determine the accuracy of data collected' The survel_llance of vlllages in the internediate zone will be coropleted during 1987' }Ilth the start of vector control acElvlEles in the v,lestern and southern Extenslon areas' interruption of transmission in the reinvasion zones is expected' The evolutlon of the Comnunity lticrofilaiial Load (cl'{FL), prevalence and ocular signs of the disease wtlL be foilowed-by regular surveillance of the villages located in these zones' In order to collect longltudlnal data on the natural evolutlon of the dlsease' 14 villages will be surveyed in the Eastern zone, six of which w111 be subjected to detalled evaluation. In the Western Extension area baseline data fron indicator villages w111- be collected to nap the distrlbution of blindness and microfilarial levels, the information belng used to select foltow-up viIlages. Simple eval'uation surveys w111 be carrled out to monitor the effectofvecEorcontrol.Thesesurveyshavealreadybeendevolvedontonationalteams. Detailed evaluation surveys will be uniertaken (a) to assess the clinlcal pLcture of ocular onchocerciasis in vlllages wlth Annual Transrnission Potentlals (ATP) in the borderllne level of tolerablliEy, (Uj io"strrdy further the severity of ocular manl'festation of the disease ln the Lnternediate zone, and (c) to dlstlnguish blinding from non-blinding onchocerciasis Ln zones where dlfferent vectors are LnvolvEa i., the transmisslon of the dlsease as a suPPort to dectsions on larvicide treatment' ocP/86.1 Page 19 Speclal studles The Farako study on the effect of interrupting vector control w111 be followed up. As larvlcidlng operatlons wl1l be lnterrupted, vcu and EPI will uonltor the rate at which an increase ln the s.-a"r"o""m population-wili affecE the ATP and new cases of infectlon in man, if any, appear. Studles to deterrnlne the impact 6f lmmigrants on the prevalence and infectlon of vlllages located in controlled areas w111 continue ln 1987, fron the ptlot studies conducted durlng 1986' A study wlII be carried out ln strict collaboratlon wlth VCU to assess at whlch 1eve1 of microftlarlal concentration a carrier becomes a source of slgnlflcant lnfectlon to S. damnosum feeafn! on-ttirn a.ra thus becomes a potential source of transmisslon. This will t "ria;-"" indlcation of the sensitlvlty that nlght be required of any diagnostic test in future. A study of different parasit.ological tests will be conducted to coEPare the sensitivity of the current OCp skln snip proceduie with the reading of skln snlps after 24 hours ln saline and the l(azzotEl Patch test. Review of cl lnlcal examinatlon Procedure A workshop on the ophthalmologlcal aspects of onchocerclasis w111 be held ln 1987' DevoLutlon The EpI Unlt will ensure the transfer of epidemlological evaluation knowledge and procedures to natlonal teams. A manual of EPI evaluation procedures ls being prepared and will be field-tested ln 19g7. Revlsion will be undertaken as needed. The trainlng of national team members w111 be conpleted in the, Western zone during 1987, when similar trainlng w111 start in the central zofle. The EpI Unlt w111 ensure selection of natlonal team members, their trainlng, assessment of the efficacy of the trainlng (quallty control tests) and re-trainlng as needed as well as provldlng suPervislon. Personnel The requlrements to carry out the above actlvitles w111 be: - Professional staff 5 - General Service staff 35 There ls a net increase of US$ 104 OO0 ln the budget provision for 1987 for this Unlt' The lncrease takes lnto account Personnel requirements lncludlng rate of exchange fluctuations partly offset by reductions in all other coEPonents. intensity of following results ocP/86.1 Page 20 TABLE 8. EPIDEMIOLOGICAL EVALUATION Category of expendlture Grade Posts Approved 1986 Proposed L987 1986 L987 RECURREM COSTS Personnel services Medical offlcers EPldeniologY Medlcal offlcers ParasitologY Medical offlcer Ophtl, almologY Laboratory, technlcal asslstants Secretary Nurse Clerks and typlsts Drivers Tenporary staff Sub-tota1 Consultants Operatlonal travel Operating costs Supplies Sub-tota1 CAPITAL COSTS Buildings Furniture Vehic 1 es Equipment Sub-tota1 TOTAL P.5 P.5 P.5 G.S G.S G.S G.S G.S 2 2 1 15 1 1 4 L4 US$ US$ 160 000 160 000 80 000 72 000 4 800 4 800 19 200 67 200 10 000 40 40 400 000 578 000 100 000 60 000 60 000 20 000 106 000 50 000 30 000 10 000 240 000 196 000 50 40 o0; 000 10 000 40 000 10 000 90 000 60 000 40 40 730 000 834 000 ocP/86.1 page 21 4.4 Socloeconomic develo t The activltles will focus on the followlng: - collection of socioeconomlc data; - collection of cartographlc data ln the whole Programme area, esPecially in the I^Iest; - analysis and dlsseminatlon of information to all the Programmers partners; - exchange of experience betl^7een the countries through neetings; - study of themes (ro1e of women, mlgration). The following activlties wll1 be carrled out: In the inltial Pr amme area: - study on the participation of women in the developrnent of areas under onchocerclasis control; - monltorlng of migrations into the protected areas (micro level); - surveys for selective updatlng of the 1985 OCP survey. In the Western Extenslon area: - collection of socloeconomlc basellne data in the extenslon areas; - preparation of basic documents for socioeconomic surveys in Senegal, Guinea Bissau and Sierra Leone; - preparatlon of a report on the original sltuation and neetlngs on the theme of mlgratlon; Cartographic study (reoote sensing: Landsat/Spot) tn hyper- and mesoenderoic zones and lndlcator hypoendenic or protected zones to evaluate land occuPancy. Personnel The unlt will have at its dlsposal: - 2 Professlonals - 1 General Servlce staff There is an lncrease of US$ 35 300 in 1987 as compared to the approved budget for 1986, most of whlch relates to needs 1n the personnel servlces (US$ 34 800) and to consultant requlrernents (US$ 19 500), partly offset by reductions i.n travel, operational costs, vehlcles and equipoent (Us$ 19 000). ocP/86.1 page 22 TABLE 9. SOCIOECONOMIC DEVELOPMENT Category of expendlture Grade Posts Approved 1986 Proposed 1987 1986 L987 RECURRENT COSTS Personnel servlces Economist Agro-economist SecreEary Temporary staff Sub-total Consultants Operational travel Operating costs Supplies Sub-tota1 CAPITAL COSTS Buildings Furniture Veh ic 1e s Equipmen t Sub-tota1 TOTAL P P G 5 3 s 1 1 1 us$ US$ 80 000 60 000 4 800 20 000 3 3 130 000 164 800 60 t2 10 10 000 000 000 000 79 500 I 000 s 000 10 000 92 000 102 500 8 10 000 000 8 000 18 000 8 000 3 3 240 000 275 300 0cP/86.1 Page 23 4.5 Applled research and environue ntal roonitorlng Insecticide research Trials of new formulations and new lnsectlclde conpounds w111 reoain the undlsputed prlorlty of the programme in 1987, even more so than in the past, conslderlng that resistance calls for the rotational use of the conplete arsenal of compounds currently avallable. Intensive screenlng of B.t. H-14 will be pursued to improve the formulatlon now used and to develop others. There wfff U. conslderable focus on formulatlons of lnsect Growth Regulators(IGRs), whtch require special Protocols as well as products belonging to new chemlcal famllles. Organophosphtrus compounds, carbamates and pyrethroids will be tested only to improve their formulations and cost-effectiveness' The soall- and large-scale screening of the effects of new products on the non-target fauna will be contlnued and if possible institutionalized in Bouak6 with the object of defining tolerabillty norns and indlcators of faunistic lmbalances. Because the loss of susceptlbility of the various species to the insectlcldes j-s a major concern, studles w111 be undertaken wlth the hope of obtainlng indicatlons of the trend of res istance. The mode of actlon of the larvicldes and their carry ln running water will be studied to hetp lmprove the efficacy of treatments. Identification of O. volvulus Identlflcatlon of the stralns (or forns) of O. volvulus in the vector is vital to lnterpretlng the cllnlcal epidemlological differences ln onchocerclasls determlning operatlonal tactlcs. VCU wl11 continue to supply lnfectlve collected irom the vector durlng entoTnologlcal evaluatlon operatlons to Trials will efficacy in resp of tsetse f1les. and, therefore, to O. volvulus larvae laboratories speclalized in high-technology differentiatlon techniques. Identiftcatlon of vectors Identlficatlon of the vectors is a maJor VCU concern. In the extension areas where the roorphometrlc types defined ln the inltial Programme area are not universally applicable, the status of roany of ttr. forms has to be clarlfted in relatlon to their variable suscePtlblllty to insectlcides and vecEor potentials and roles. Bloecology The study of the duratton of larval life accordtng to specles and seasons (malnly water temperature) wfff be contlnued to optlmlze treatment rhythms in dlfferent biocllmatlc zones. Operatlonal research Knowledge of the correlations between hydrology and blackfly productlvlty will also have to be lmproved ln o::der to adapt treatment tactlcs to the seasonal and loca1 epldenlological rlsk, ani to enable Judicious and econooica.l postponements and suspensions of larvicidlng. Ihls study w111 be greatty asslsted by the Argos hydrological teleEransmlsslon network being extended ln the area whlch, among other things, can also be utlllzed for a recording of the lrater teEperature of the breedlng sites (see above)' Mlgratory behaviour (catches, f1y-trappinS, cytotaxonoulc ldentificatlon of larvae and ngorphometrlc ldentificatlon of females) w111 naturally be rnonltored carefully during treatoeot of the sources of reinvaslon. be nade to perfect existlng fly-trapping devices, particularly to test the ect to S. damnosum s.1. of certain traps recently developed for the capture The taxonomic, morphometrlc, bioecologlcal and vectorial characterlstics of S. dieguerense in the Western Extension area (the only reglon where this species has been notea) will be studied urgently before larvicidlng covers the whole area. ocP/86.1 Page 24 Entomo -eplderoiologlcal research A speclal study will be carrled out of S. damnosum couplex in relatlon to each othe savanna sPec ies, recentlY noted in the more the seasonal roovements of Ehe specles of the r, especlally to determine tf the lncrease in huroid southern zones, constitutes a seasonal lts eplderoiological slgnificance will also bephenomenon or a more durable colonizatlon; investlgated. Special attention will be paid to the problen of slight lnfestations and/or old infestatlons; experiments are planned to estimate the lnfectlve Potential of carriers of such infestations by dlfferenr itrains of o. volvulus ln relation to Ehe three roajor pairs of cytologlcal vector sPecles. An attenpt will also be made to deternine the epldemiologlcal significance of the 1ow ATps and to redeflne their lower level of Colerabillty fixed, for the moment, at 100. The study of the butld-up of the vector population in a focus virtually cleared of onchocerclasls (e.g. Farako) is topical and in PreParatlon, but it ls advlsable to walt to have a sinpJ-e and Effective drug to be in a position to neutrallze new infections should they appear. Tiris study should prefigure the sltuatlon that w111 prevall after systematlc vector control ceases. VCU will participate ln the experinenE on the effects of mass treatment with lvermectin by oonltoring, before, durlng and after the appllcatlon of the drug, the varlatlons ln the lnfestatlon of the vector populations by 0. volvulus. VCIJ wlII partLcipate, as much as possible, in Jolnt studles wtth EPI and ECo alned at obtalnlng an lntegrated plcture of the epidenlology of onchocerclasis' Aquatic monltor ins The routine hydroblological monitoring w111 contlnue to be carrled out by the natlonal teaDs. Research w111 be carried out on entonological and ichthyological assoclations, dynamics of lotlc populatlons, a comparison of the effects of natural and anthropic factors on the one hand, and antl-blackify t".rf"tding on the other hand. Protocols w111 be developed for the Eonltoring of crustaceans. Savanna onchocerciasis and forest onchocerciasls The epidemlological investigations of vlllages wlth respect to the savanna and forest probleos will continue. Enphasis w111 be laid on the lntermedlate zones. For that purpose' detailed evaluation will be carrled out in such biotopes in C6te drlvoire and will complete those of slnllar zones in Guinea. The biological Lnvestigations on the aspects of the dlfferent forms of the parasite are to continue. These will lnvolve the use of DNA technology, enzyme electrophoresls and immunochemLcal nethods. Anong the laboratorles involved ln these Programmes, only one has a contract wtth OCp, the renewai of which will depend on the results obtained. A11 the laboratories will be supplied wlth biologlcal material from ocP. Imrnunodiagnos tic research A population of children llvlng in an area of ongolng transmisslon has been followed up for several years to assess the sero-conversion durlng the pre-patent period. The fol1ow-up wlll continue in 1987. A number of laboratories are lnvolved in the develoPnent of an Lnmunodiagnostic test. Although no flnancial support i.s generally provided by OCP, the field studies and field work to collect ""a" ..ri p"r."it." and to test reagents are planned as a counterPart of Ehe work to be done in high-tlchnology laboratorles. The main targets are to produce specific monoclonal antlbodles and to-characterlze genes encodlng for speclfic antigens of 0. volvulus' ocP/86.1 Page 25 A special effort w111 be made to collect and cryopreserve parasites for further use 1n l-ive conditions. Thts w111 require surveys and field experiments in the OCP uncontrolled area to ensure suitable materlal. Parasite longevitY and fertility Ihe villages assessed. study on longevity of the adult parasite will continue by the follois-up of slx in the central OCP area. The evolution of nortallty bethTeen the t.wo surveys will be a Following completion of studies to develop a method for the of the nale worm, the nethod will be applied in several villages the uncontrolled area for comParison. assessment of the fertilitY of the controlled area and The followlng resources w111 be requlred to carry out the above progranme: - Professional staff 10 - General Servlce staff 43 There is a net increase of US$ 91 400 in 1987 as coopared to the approved budget for 1986. The personnel services requlreurents had to be increased to take account of fi1led posltlons, iate of exchange fluctuations as well as six new posts In the General Servlces category. Other lncreases relate to travel, buildlngs and furniture (US$ 20 000). There are reductlons in consultant services (US$ 34 000), operati.ng costs (US$ 41 000), neetings(us$ 25 000), vehicles (uS$ 50 000) and equipment (us$ 5000). ocP/86.1 page 26 TABLEI0.APPLIEDRESEARCHANDENVIRoM'IENTALMoNIToRING Posts Proposed L987 Approved 1986 1986 L987 GradeCaregory of exPenditure 480 000 240 000 43 200 4 800 r_58 400 us$US$ 6 4 9 1 33 P5IP4 P3lPl G.S G.S G.S 926 400700 00047 53 106 100 600 79 50 000 000 000 000 000 140 90 600 L20 50 25 000 000 000 000 000 000 935 000I 025 000 10 000 10 000 20 000 000 000 000 000 5 5 50 25 40 00085 000 1 901 4001 810 00047 53 Sclentlsts Asslstant and technlcal offlcers Technical asslstants Clerk steno tyPist LaboratorY assistanE, drlvers and others Sub-tota1 Sub-total Sub-tota1 TOTAL CAPITAL COSTS RECURRENT COSTS Personnel servlces Consultants Operatlonal travel Research contracts Operating costs Supplies Meetlngs Buildtngs Furniture Vehlcles Equipment I ai 0cP/86.1 PaEe 27 TABLE 11. APPLIED RESEARCH AND ENVIRONMENTAI MONITORING - ST]MMARY BY CATEGORY OF EXPENDITURE AND BY SECTION: 1987 4.6 Onchocerclasis Chenothera py Proiect (0CT) Cllnlcal trlals of lvermectln and Clba-Geigy Compound 6140 w111 contlnue wlthln and outslde the OCP area. 1. Ivermectln. concurrent rrlth registration of lvermectln for use ln man, advanced Phase IV studles ln the field w111 be carried out. 2. CGp 6140. phases II and lII studles will be exEended to lnclude rnultlple dose scneaffiana w111 requlre associated advanced human pharmacology and anlmal toxlcology. oCT wtl1 continue to fund anlnal studies to investlgate the potential use of lvertrectin ln conJunctlon wlth other drugs, and lts posslble contralndlcation 1n concurrent lnfectlons such as bacterial nenlngltls and sleeping sickness" The Onchocerclasis Chemotherapy Research Centre (OCRC) ln Tamale, Ghana, ls the only centre, fu1ly supported by gCT, capable of carrying any Potential drug through Phases 1 to III of lts elinical trlals both lnside and outslde the OCP area, and lEs Director is euployed as a WHO consultant for onchocerciasis. Due to t.he success of the vector control Programme in the Tamale patient catchment area, an elternate hospital slte ln Southern Ghana is being investlgated. Refurbishing of the hospital facllltles will lnvolve additional expense in 1987, and posslbly 1988. Sectlon Category of expenditure Envlronmental monitoring and hydrology Entomology and lnsect lclde teaos Epidemlology Soclo-economic Total RECURRENT COSTS Personnel servi.ces Consultants Operatlonal travel Research contracts Operatlng costs Supplies Sub-tota1 CAPITAL COSTS Buildings Furnlture Equlpuent Sub-total TOTAI US$ 392 800 31 800 40 000 150 000 20 000 10 000 US$ 466 400 42 400 50 300 350 000 40 000 30 000 US$ 67 200 2t 200 7 300 50 000 13 000 5 000 US$ 10 600 2 400 50 000 6 000 5 000 US$ 926 400 106 000 100 000 600 000 79 000 50 000 644 640 979 100 i63 700 74 000 1 861 400 5 000 5 000 10 000 5 000 10 000 3 000 2 000 10 000 10 000 20 000 10 000 25 000 3 000 2 000 40 000 654 600 1 004 100 166 700 76 000 I 901 400 ocP 186.L Page 28 The OCp nobile team consisting of a cllnician and an ophthalnologist will continue to be supported If personnel are available. VJtthin the next budgetary period, it is probable that one or the other of the Eaior industrial research groups supported by OCT will need to undertake extensive pre-cllnical studies in drug metaLolisn, tlxicology and pharmacology in suPport of their most active lead comoounds. To take such a drug to the stage of Phase I clinical trlals could cost ;;il;;i;;;ely us$ 1 ml1lion ln roral, and in additional US$ 0.5 nillion nav be required durlng the period 1987-1988 for thls purpose' I Cattle infected with 0. g lbsonl and O. gutturosa provide the only experloental system in whlch compounds can be tested for ant i-Onchocerca actlvitY, and OCT w111 continue to suPPorts work. Nodules of :ory for dlstribution tothe screening centre ln Townsville, AustralLa, whi ch carries out thi 0. glbsonl and llve lsolated worms are also provided by this laborat OCT-supported cheootherapy research groups throughout the wor1d. Lymphatlc and dernal fllarlae nust still be used for prlmary chenotherapeutlc testing ln rodents and other sna1l laboratory animals, and OCT will fund a screenlng centre in Glessen, Federal Republic of Gernany, to carry out such work, together wlth dlrect lnhibitory studies of Onchocerca species ln in vltro culture. The two industrlally based integrated research groups proposed originally for OCT and l0cated ln Great Brltaln and unlted states of Amerlca are now fully oPerational and forn the maJor research efforts of 0CT. Research for basic studies on the biocheoistry and In vltro culture of Onchocerca and other filarial species will contlnue to be carried out under contract with acadenic lnstitutions. Research has reached the stage where fresh Onchocerca materlal has to be used.Forfie1dworkonthebiochen1stryaid1nvitrocu1@andQr.g1Fson1, travel funds, and addltional laboratory supplies, will be provlded to OCT-supported workers to carry our essentlal research projects rliutrtng freshly isolated adult rdorms, both in the OCP area and in other areas where sultable material can be obtained' Regular supplies of live sauples of O. volvulus are provided to research workers throughout the world for OCT-funded pro5ects, nalnly froD Guatemala, with sone ltorms coning frorn Mexico, and the conblned cost of this supply ts us$ 75 000 per annum' Recordlng and processlng of chemotherapeutic screening results fron laboratory fllarial nodels wllt be carried out iointly with TDR/FIL- A sma1l cotrputer to handle this wtl1 be purchased in l-987. The following personnel resources will be required !o carry out the above PrograEne: - Professional staff I - General Service staff I There is a net increase of us$ 22L 5OO ln 1987, of which us$ 27 900 relate to personnel- costs. There is also an increase in research contracts of US$ 200 000 and parEly offsetting reductions in the provlsion for consultants (US$ 6400) ' a 0cP/86.1 paSe 29 a I Scientist Secretary (Geneva) Consultants Operatlonal travel and others Research Operatlng costs Supplies Meetings TABLE 12. ONCHOCERCIASIS CHEMOTHERAPY PROJECT Sub-tota1 RECURRENT COSTS Personnel servlces TOTAL Category of expendlture Grade Posts Approved 1986 Proposed t987 1986 1987 P.5 G.S 1 1 us$ US$ 80 000 47 900 2 2 100 000 127 900 70 000 10 000 3 000 000 10 000 5 000 70 000 63 600 10 000 3 200 000 10 000 5 000 70 000 2 2 3 265 000 3 486 500 ocP/86.1 page 30 TA3LE 13. ONCHOCERCIASIS CHEMOTHERAPY PROJECT: RESEARCH CONTRACTS a I ConEracts Approved 1986 Proposed 1987 IVERMECTIN(Vector transuisslon studles) FLUBENDAZOLE (Screening and toxicologY) CIBA-GEIGY(Pre-c1lnica1 toxlcologY) ONCHOCERCIASIS SCREENING CENTRES INDUSTRIAL RESEARCH GROUPS BASIC RESEARCH GROUPS MOBILE TEAM OR OTHER ASSISTANCE FOR CLINICAL TRIALS SUPPLY OF NODULES DATA PROCESSING TOTAI us$ 270 000 80 000 2LL 335 L L76 592 2s6 50 30 000 000 000 000 000 000 000 us$ 220 000 300 465 I 362 508 260 75 10 000 000 000 000 000 000 000 3 000 000 3 200 000 a ocP/86.1 Page 31 4.7 Admlnls tration and SuPPort Services One characterlstic of the AdrnlnLstratlon and SuPport Services 1n 1987 will be the coosolldatlon of the resources that have been shifted to BaBako to suPPort a full-scale larvlclde attack by the time the rainy season arrives in an area deslgnated as "oPeratlonal phase VI" (see Annex 8). The Bamako contingent of the Admlnlstration and Support Servlces will conslst of 39 General Service staff and one Professional administrator, under the direct supervlsLon of chief Adnlnistratlon Manageoent. Thls is intended to provlde coordinated nanagement of personnel, finance, supply, transPort and common servLces. In line wlth the recommendatlon of a transport management survey' OCP will strengthen the Eanagement of its transport operations by creaEing a senlor administrative assistant post in guagadougou (ln lieu of Professional post) and a slnilar post ln Bouak6. Moreover, operations rftt U" further supported by a new post of service oanager in the Bouak6 Sarage and an additional post at the central supply store ln Ouagadougou, making a total of four new posts in 1987. The rigour of 10 years of contlnuous operations plus a requirement to extend radio communLcatlons rrestrf,ard gave rise to an evaluation of the entire radlo network ln 1986. The resultant mlssion to upgiade OCPrs communlcaEion system wll1 continue in 1987. The total estlnated cost to meet coErtrunlcatlon requlrements for Phase IlI (1986-1991) is of the order of US$ 580 O0O of which the najor Portlon is budgeted for 1987. It will be recalled that the 1986 Plan of Actlon and Budget emphasized the need for an alrcraft to servi.ce the prlncipal 10 or 12 localltles in the Programme area. lnstead of hirlng an alrcraft, it wis decided to nake provlslon for the deslred servlce as part of the fifth aerial spray contract (1987-1989). Finally, a determined effort to contaln Programme costs w111 focus on a cost-consciousness canpalgn partlcularly concernlng staff travel and the curtallnent of oarglnal actlvltles. Required resources to lnplement the above are: - Professlonal- staff 11 - General Servlce staff L65 - OCP Ouagadougou 122 - OCP Bamako 39 - Support staff Geheva 4 There ls a net increase for Adrolnistratlon and Support Servlces for 1987 of US$ 420 8OO. Salary requirements have had to be substantially lncreased because of the rate of exchange for the CFA (US$ 177 000), the ineluslon of seven new posts ln the General Service category (US$ 33 600), ternporary staff provislon (US$ 39 200), and statutory costs and restoration of the delay factor applled for the 1986 estimates, slnce.by the tine of preparatlon of the 1987 budiet all posts but one were actually filled (US$ 313 200). An lncrease of US$ 100 OO0 ls also provided in order to purchase sone basic mechanlcal equipment to be located 1n the Western zone offlce of Banako. To offset these lncreases, reductions totalllng VSi 242 200 have been effected in the provlslon for consultants, aerlal operatlons(transferred to VCU as an integral part of the aerial contract), buildings, furnlture and vehlcles. l I - ocP/86.1 PaEe 32 TABLE 14. ADMINISTRATION AND SUPPORT SERVICES Posts Proposed 1987 1986 L987 Approved 1986GradeCategory of exPenditure 80 BO 80 160 60 60 60 60 60 60 000 000 000 000 000 000 000 000 000 000 US$ 100 384 288 191 39 800 000 000 000 200 US$ P.6 P.5 P,4 P.4 P.3 P.3 P.3 P.2 P.2 P.2 S s s s G G G. G. 1 1 I 2 1 1 1 1 1 1 2t 80 60 4 1 763 0001 200 000L69 L76 137 800 90 000 220 000 130 000 150 000 90 000 220 000 130 000 60 000 577 800650 000 40 000 30 000 20 000 150 000 80 70 110 50 000 000 000 000 240 000310 000 2 580 8002 160 000L69 t76 Adrolnlstrat lve of f lcer Personnel offlcer Budget and fLnance offlcer Adolnistrat lve of f lcers Personnel offlcer Flnance offlcer Supply offlcer Budget offlcer Personnel offlcer Admlnietratlve of f lcer Admlnistratlve and technlcal asslstants Clerks and typlsts DrLvers and messengers Geneva supPort staff Teoporary staff Sub-total Sub-cota1 Sub-total TOTAL CAPITAL COSTS Consultants Operatlonal travel Operating cosEs Supplies Aerlal operatLons RECURREM COSTS Bulldlngs Furniture Vehlcles Equipnent I a ocP/86. 1 page 33 olr)uHi r!E ulooHO. X OJ oo o\ oooooooooooooo -?NoCooo\:f, \0666NO@ NN.$\!.CO\O\t N.a..{.,trdN <, a oo @ o @ N ! F o EA d td oooooo oono ,_.t a c) oo 4 o 0) d o OJ oo o N 4 6 o o N c) k I d ! t& o o o .A ooo o o0 d il a ,a ooo o -+ V) ooo \' (, I tritr5(!O!! !d O lr!u5Cto 0J!o o5&xo o o 0) i U) o F{ Or d oooooooooooooo sNO@OO\t oo61r)rO@NN-r6€6-tNOil.n\ON * 6 5 o @ o\' N oooooo oo cio 4 U) oo o d q u o U hod u dtr 0) o. o oooooo oo(?) o {/) U)5 oo o N N d6trdood>u6l!lrHU 0) o. o o ooooo<)ooooooooo n66nodd\, a o5 oo o o\ o I dp o o o o oooooo @@N ilid o.7)N o 0 oo @ N d AO ooC.) c.do> olrlr €) o@A oo i 6 r-i \t @ N ooooooooooo\t@coo OroNOsN@d\O-?NNi6O {A u) ooo \o r r-{ t o .i ! (,) oa 6' H p i o x! @ o! r0(J J H H (! qJ e)() 6c0)oo .d .d!>(!uPo !(r0Jo uooo?) oEo.d .iaoo>d ta>o}]o .d.A.i(u.4 E!!>outd(i!666!uoi! ouFoo!ioooocqdu.d.ro.cd.i!dddqoot u (!d.d6eortrtroeC6Erreoir'o!oo,t 0, o N ! o o3 1,d l(! lo lhot,loIrl(!IM l9 lo d o .rt u d}] o d E a, r @6 d z HH(J rd tJ) la oz rt1d FrH o2 rd 0{X r,l ho doI tdH o la 4 J 2, .J) I .A rr:oH d rI]IA HdoA Or =o o2 zoHH d H u) FizH a d T{ ,J .a ocP/86.1 Page 34 4.8 ![eetings The provision for meetings includes travel and per diem for ParticlPants and supPorting staff, as well as translaEion of documents and iuterpretation services' The ueetlngs planned for 1987 are: - one session of the Ecological Group; - one session of the Expert Advisory Comnitteel - one session of National Onchocerciasis Cornmittees; - Ewo sesslons of the Committee of Sponsoring Agencies; - one session of the Joint Programme CommitEee' In addltlon, the estinates cover other technical neetlngs, semlnarsr etc., to be convened bY OCP. TABLE 16. MEETINGS t Category of exPenditure Approved 1986 Proposed 1987 Meetings US$ 310 000 us$ 320 000 TOTAL 310 000 320 000 ocP/86.1 PaSe 35 ANNEX 1 AVERAGE COSTS USED FOR BUDGETARY CALCULATIONS Professlonal D2-P4 P3-Pl General service/OCP General service,/oCP Geneva Consultants Incentive paynent to national staff Aerial oPerations (without fuel) Staf f Insecticides B.t. H-14 (HPD) Per Fmephos (Abate) Per Chlorphoxlm Per Permethrln Per Carbosulfan Per Cost per flYing hour Helicopters and fixed-wing aircraft Liaison alrcraft 1987 US$ 80 000 60 000 4 800 47 900 5 300 900 555 189 litre lltre litre litre litre 8. 60 11. 40 7.80 L6.20 25.80 Value of US dol1ar (May 1986) CFA franc French franc Swiss franc Pound sterling D. mark Canadian do1lar 345 6. 90 L.82 o.645 2.L7 1. 38 ocP/86. 1 page 36 AI.INEX 2 EASTERN ZONE Kara Sector Sub-sectors.' Kara (Togo) Atakpan6 (Togo) Nianey (Nlger) Ouagadougou (Burkina Faso) Tamale Sector Sub-sectors: Tanale (Ghana) Bolgatanga (Ghana) Kintanpo (Ghana) Hohoe (Ghana) Parakou Sector Sub-sectors: Parakou (Bentn) Kandi (Benin) Natltlngou (Benin) Bohicon (Benin) CENTRAL ZONE Bouak6 Sector Sub-sectors: Bouak€ (C6te drlvoire) Segu6la (C6te d'Ivoire) Korhogo (C6te drlvolre) Bondoukou (C6te drlvoire) Bobo-Dioulasso Sector Sub-sectors: Bobo-Diou1.""o1 (Burkina Faso) Slkasso (Mali) WESTERN ZONE Barnako Sector Sub-sectors: Bamako (Mali) Bougouni (Malt) Klta (I{ali) Toukoto (Ma1i) Baf ou1ab6 (I'la1i ) Manantali (Ma1i) Odienne (C6te drlvoire) VCU ENTOMOLOGICAL EVALUATION NETWORK (1987 ESTTMATES) I(ayes Sector Sub-sectors: Kayes (Mali) Kenieba (MaIi) Fari-Ndjari (Mali) Kankan Sector Sub-sec tors.' I(ankan (Guinea) Kerouane (Guinea) Beyla (Guinea) Kissldougou (Gutnea) Niagassola (Guinea) Siguirl (Guinea) Dabola Sector Sub-sectors: Dabola (Guinea) Faranah (Guinea) Dinguiraye (Guinea) Kouroussa (Guinea) Lab6 Sector Sub-sec tors : Lab6 (Guinea) Mamou (Guinea) Malt (Gutnea) Gaoual (Guinea) Boke (Guinea) Tambacounda Sector Sub-sectors; Tambacounda (Senegal) Kedougou (Senegal) Makeni Sector Sub-sectors: Makeni (Sierra Leone) IGbala (Sierra Leone) Port Loko (Sierra Leone) Gabu Sector Sub-sector.' Gabu (Guinea-Bissau) a I Including Bandiagara (Mali). ocP/86. 1 page 37 ANNEX 3 -t(, ! o ts rn (') \O \O tn r^ O (n tn -t rn d) q C: -l - '{ c\'l o\ c) (o.1 FI cl .s a IHH H (! lrOHtroo .r{ o(/)FI \ollllllF\N(no\r-{': rn.$ rd o,) F .r{ lcll'-{Nll'$FiItlll o -{ z IH HH I(!, o(0 dth 'ri (,,),A()Fo I r-.1 i -l I ci 4 r'{ ") r-{ I \O r-l @F.t (! o .r{ (, I c'.1 .-{ttttr.rtt,it ttl H H F{(0 @ o Q 0)(A o.t\o FtFtl.$l-{l€)slN(a Fl o\.'f 6 0) a ?{) IttF{-?l16ll@(\tl o GI (7) IH (0 o c .r{ a(, 6l cl N $ Fl C! l-\ N r\''{ A N S! r\ -{ c\ (f) No F.{ N IH .Fi F-{(0 r\rnFllco Gt(Y) .+Fo c.llF{lF{lFt r{ FI F{ (0 o c a(J l-llFl-l!l6tri \o F.l I l-{ (B o F .F{)(J F{ Fl (\ 6l F{ cl r\ 6l dl 't F{ r'{ '$ 'SF.{ -l !n o th(0 A{ ht{ lld o C) !d u(!qr!!E ''-{ O U, r0 !@ .r{ .Fl 5{ tr oo0oo(0FIO'D'r{! o;(slHftt'tiEci'-oia'r{o5to.J';ool!n€>Eolooo +rE;r{'Urrd!6.l6!0h'urur'-{;odt.\>\lio.lr'loi;!!i.oqo!qao5"i,oeEr:ndoo.oroq;od6@o;rJood<oci ; ri +i'rr o A d tr .9 ro rr SFroood6EnooolE04H;J'f;ioo"{>p!r+J(J n "dooE'ouE!'AOGq!EXtiq€atr(d({rr!oo.6 ,r HoH !&t{2p o() o2 frl(r, A oH C)zH ad,a(J o zoHH p -r frl &ofq A E]&Hir rr1& tu tq H a FI zoHH z a ocP/86.1 Page 38 ANNEX 4 PERCENTAGE OF OCP STAFF BY COUNTRY OF ORIGIN(1 JULY 1986) on 1 July 1986: 95.9% of the staff came from Afrlcan countries south of the sahara, 95.3% from v,lest African countries and 50.9% of the professional staff were nationals of countries participating in the Progranme. Note: Country Professlonal(%) General servlce (7") Percentage of total Afghanlstan Belglun Benln Burkina Faso Caneroon Congo C6te dr Ivoire Federal Republlc of GermanY France Garnbia Ghana Ireland Italy Japan Lebanon Madagascar I'la1i Netherlands Nlger Senegal Spain Swltzerland Togo Unlted Klngdon Unlted States of America L.96 L.96 3.92 15. 69 0.00 1. 96 1.96 1. 96 9. 80 L.96 9.80 L.96 3.92 1.96 1. 96 1. 96 7 .84 1. 96 0.00 3.92 L.96 L.96 7.84 7.84 3.92 0.00 0. 00 13.09 32.57 0.15 0.00 L7.35 0.00 0.61 0.00 11. 57 0.00 0.00 0.00 0.00 0.00 LL.42 0.00 2.L3 0. 00 0.00 0. 15 10.65 0. 30 0.00 0.14 0.14 L2.43 31. 36 0.14 0.14 L6.24 0. 14 L.27 0.14 LL.44 0.14 0. 28 0. 14 0. 14 0. 14 11. 16 0. 14 1. 98 0. 28 0. 14 0.28 10. 45 0. 8s o.28 TOTAI. 100.00 100. 00 100. 00 ocP/86. 1 Page 39 ANNEX 5-id! oH o -{o-t.{6t€(.)F\.+ r{ (O .-lGI .{o !Fl.f ,F.]radtstrrO-, tr&(d lllrnNrnl N -t oJ (,,) trH (,,AO-+ -t, xO.+ OvtlO,HE\O ttllr-trn \o o o OH ol{\O q) E l\Ol \o ! -{Ha(dnt.od)& F{t(r) ,-ll.{l oo.,l o +J ox oH B !a ttI F{ o{ tO N o F{ x a Fl .r{ 6t o.lC')o\ottr N\o . .'? .Bd.x FI Ur.t -t$FIllln N s @ o@ .a trB ! €'-{r.d tr A >c6E .F{ (tEC) II o.l ri Fl \o o Fl ! o(u @) oA p or (f) 6lIFl .$I ..{ tn olro B JJa ttIr\ ,{(v)I oN o o ..{ da IN -lN-rrnl .,i'Fl ! .,i d @t ..1 L o TJ !'.{ .r ddo 60ooEooE .r{ O Fi '!d-ltr(!+{ o o (!uO 'r{ O oCrJo.O0)o (! (uE - lr u !C!!lroO o O !! (U O tr o 'A> IrO .H I el tr aJlr E (0 = H o.O o .F{'UH()ATO.C, J HoH a \o co o\ -t tsJ5h -t(Y) ho tn (n rI] .I(J HE 14 A(J o jltroo,@rrd!trrlBvo ol@>c o(6 0oa>& ."{lo +rll! t! O-l d!.Fl O 6(,or>J [[[il t! .PBE (aA>F] ocP/86.1 Page 40 ANNEX 6 vEHrcLE REQUTREMENTS 1987 a Unit Ltghtvehicles Trucks Total Directorrs Offlce vcu EPI Admlnistration 1 31 1 2 1 1 1 32 2 2 TOTAL 35 2 37 a ocP I 86.L Page 41 ANNEX 7 t t trj + g. (, :<o U o 'ti .a /t 'E U Ji,t.*,. 2 \ ) ) lrl = zU Y 5oo t t9 t98 1Hft' I + + z c) 6 d U o lJ ,o UUE EY zoo -l- t\ z @ F,- x LrJzz + tn trj zoN Z aF :l) lrj oz u) tr,t _) z aF E. UJ o-o + ) a. + ea '.-.> t. t>\ E 6 @ \/l \ ) i + f + 8 g 9 + f s + *"*s ocP I 86.L page 42 ANNEX 8 @ x trJzz l(J ILo a trla T o_ J z aF x. trJ o-o |. t, a @ o 6 ocP/86. 1 PaSe 43 ANNEX 9 .gEz9b OEoo Eg8€ E IG - oo €cc €i:E{UUFUic -o ts5eff8H E '6' o =559!l ':6 u*B E oo <o o EE : H,P T.E 6;E FE!giE-'. ooL9 c- cO. !'E Iq= E oE OH EOo=(Jr d Pt EEE}dc-ua .a!9! Q;di o PE oi.EN ;,i E; a co (5 8l .E ocoo>o 3 c -O EEa =ob E EA<oco I '.4 E! E oFou G, 6 U2 =E o o .Er c o ,a -oEi! E8 cEo IB o E o P ii EI o F i c E.g E.9 EEUE ! c 8- =a faol- c .9 !I F !E oc!alcOE c .8!o Li; ab s 2 o 5c cI G c E , oo c .9 E o s a cgiodo c6 too .!: EJO(, iiI3€ e6 :.: TJE H t :l 6 @ o J f r o o u E, f, Fol Fo U E E(9 o c , ) I i